Old Protein, New Medicine
As a member of the protein family known as neurotrophins, brain-derived neurotrophic factor (BDNF) plays a crucial role in supporting healthy brain function, which includes synaptic plasticity, cellular differentiation, learning, and the survival of nerve cells. Neuronal plasticity refers to the ner...
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| Формат: | Online |
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| Язык: | английский |
| Опубликовано: |
IntechOpen
2024
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| Предметы: | |
| Online-ссылка: | ONIX_20240307_9781837693139_323 |
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Нет меток, Требуется 1-ая метка записи!
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| _version_ | 1869515252054360064 |
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| collection | Directory of Open Access Books |
| description | As a member of the protein family known as neurotrophins, brain-derived neurotrophic factor (BDNF) plays a crucial role in supporting healthy brain function, which includes synaptic plasticity, cellular differentiation, learning, and the survival of nerve cells. Neuronal plasticity refers to the nervous system’s ability to adapt and respond to environmental conditions, involving various structural and functional mechanisms that can lead to changes in neural circuits, the formation of new synapses, and the generation of fresh neurons. BDNF has emerged as a significant regulator of neuronal plasticity. It is worth noting that the pathophysiological processes underlying central nervous system disorders and neuropsychiatric conditions such as depression, anxiety, autism, and schizophrenia, as well as neurodegenerative diseases like Parkinson’s and Alzheimer’s, are influenced by BDNF. Due to its robust neuroprotective properties and recently discovered anti-inflammatory and anti-apoptotic characteristics, BDNF has long been considered a potential candidate for preventing neurodegeneration. In the context of autism spectrum disorder, BDNF holds great promise as a central focus for therapeutic efforts. Its significance extends to the field of spinal cord injury, where it assumes a multifaceted role in the intricate pathophysiological processes at play. BDNF functions as a catalyst for the growth of axons, a crucial step in the restoration of the nervous system following damage. In the context of sepsis, research into the potential of BDNF’s anti-inflammatory properties to mitigate organ damage is quite noteworthy. Additionally, current findings suggest that combining exercise with vitamin D may offer a promising approach to increase BDNF levels and improve brain health. This book presents comprehensive information on BDNF and its role in promoting neuroprotection. The chapters offer insights into recent developments, molecular principles, and innovative therapeutic approaches for neurodegenerative disorders and brain health. |
| format | Online |
| id | doab-20.500.12854ir-135414 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1354142024-04-05T12:35:30Z Old Protein, New Medicine Erbaş, Oytun Altuntaş, İlknur bdnf inflammation oxidative stress biomarker sepsis ketamine thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences As a member of the protein family known as neurotrophins, brain-derived neurotrophic factor (BDNF) plays a crucial role in supporting healthy brain function, which includes synaptic plasticity, cellular differentiation, learning, and the survival of nerve cells. Neuronal plasticity refers to the nervous system’s ability to adapt and respond to environmental conditions, involving various structural and functional mechanisms that can lead to changes in neural circuits, the formation of new synapses, and the generation of fresh neurons. BDNF has emerged as a significant regulator of neuronal plasticity. It is worth noting that the pathophysiological processes underlying central nervous system disorders and neuropsychiatric conditions such as depression, anxiety, autism, and schizophrenia, as well as neurodegenerative diseases like Parkinson’s and Alzheimer’s, are influenced by BDNF. Due to its robust neuroprotective properties and recently discovered anti-inflammatory and anti-apoptotic characteristics, BDNF has long been considered a potential candidate for preventing neurodegeneration. In the context of autism spectrum disorder, BDNF holds great promise as a central focus for therapeutic efforts. Its significance extends to the field of spinal cord injury, where it assumes a multifaceted role in the intricate pathophysiological processes at play. BDNF functions as a catalyst for the growth of axons, a crucial step in the restoration of the nervous system following damage. In the context of sepsis, research into the potential of BDNF’s anti-inflammatory properties to mitigate organ damage is quite noteworthy. Additionally, current findings suggest that combining exercise with vitamin D may offer a promising approach to increase BDNF levels and improve brain health. This book presents comprehensive information on BDNF and its role in promoting neuroprotection. The chapters offer insights into recent developments, molecular principles, and innovative therapeutic approaches for neurodegenerative disorders and brain health. 2024-03-07T17:20:36Z 2024-03-07T17:20:36Z 2023 book ONIX_20240307_9781837693139_323 2632-0983 9781837693139 9781837693122 9781837693146 https://directory.doabooks.org/handle/20.500.12854/135414 eng Biochemistry image/jpeg n/a https://www.intechopen.com/books/13042 https://mts.intechopen.com/storage/books/13042/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.111201 10.5772/intechopen.111201 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781837693139 9781837693122 9781837693146 IntechOpen 47 128 open access |
| spellingShingle | bdnf inflammation oxidative stress biomarker sepsis ketamine thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Old Protein, New Medicine |
| title | Old Protein, New Medicine |
| title_full | Old Protein, New Medicine |
| title_fullStr | Old Protein, New Medicine |
| title_full_unstemmed | Old Protein, New Medicine |
| title_short | Old Protein, New Medicine |
| title_sort | old protein new medicine |
| topic | bdnf inflammation oxidative stress biomarker sepsis ketamine thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| topic_facet | bdnf inflammation oxidative stress biomarker sepsis ketamine thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| url | ONIX_20240307_9781837693139_323 |