Recent Advances in Bacterial Biofilm Studies

Bacterial biofilm is a complex structure with diverse bacterial cells in a highly organized and ordered group within a matrix of extracellular polymeric substances they produce. Microbes attach to surfaces to develop biofilms, a sophisticated process regulated by factors such as nutritional status a...

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Хэвлэсэн: IntechOpen 2024
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Онлайн хандалт:ONIX_20240307_9781803567099_348
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collection Directory of Open Access Books
description Bacterial biofilm is a complex structure with diverse bacterial cells in a highly organized and ordered group within a matrix of extracellular polymeric substances they produce. Microbes attach to surfaces to develop biofilms, a sophisticated process regulated by factors such as nutritional status and biotic/abiotic surface features. An established biofilm structure mainly comprises bacterial cells, proteins, nucleic acid, and exo-polysaccharides that are extracellular macromolecules excreted as tightly bound layers in microbes, providing a perfect niche for bacteria to exchange genetic material between cells. In addition, bacterial cells in the matrix also communicate via quorum sensing, which greatly impacts biofilm processes. Under clinical circumstances, bacterial biofilm shows great resistance to antibiotics, disinfectants, and body defense systems, making it difficult for clinicians to eradicate and facilitate many infectious disease processes, leading to chronic infections of patients with long-term hospitalization and high mortality rates. Therefore, it is very important to understand the recent advances in forming, regulating, and eradicating biofilms in human infections to better prevent, control, and treat biofilm infections in humans. Written by an international team of basic and clinical researchers, the chapters of this book provide novel insights and advanced knowledge for life science researchers, clinical researchers, doctors, and other interested readers on some of the latest developments in biofilms.
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spelling doab-20.500.12854ir-1354392024-03-31T22:45:41Z Recent Advances in Bacterial Biofilm Studies Wang, Liang Gu, Bing Zhang, Li Zhu, Zuobin thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases Bacterial biofilm is a complex structure with diverse bacterial cells in a highly organized and ordered group within a matrix of extracellular polymeric substances they produce. Microbes attach to surfaces to develop biofilms, a sophisticated process regulated by factors such as nutritional status and biotic/abiotic surface features. An established biofilm structure mainly comprises bacterial cells, proteins, nucleic acid, and exo-polysaccharides that are extracellular macromolecules excreted as tightly bound layers in microbes, providing a perfect niche for bacteria to exchange genetic material between cells. In addition, bacterial cells in the matrix also communicate via quorum sensing, which greatly impacts biofilm processes. Under clinical circumstances, bacterial biofilm shows great resistance to antibiotics, disinfectants, and body defense systems, making it difficult for clinicians to eradicate and facilitate many infectious disease processes, leading to chronic infections of patients with long-term hospitalization and high mortality rates. Therefore, it is very important to understand the recent advances in forming, regulating, and eradicating biofilms in human infections to better prevent, control, and treat biofilm infections in humans. Written by an international team of basic and clinical researchers, the chapters of this book provide novel insights and advanced knowledge for life science researchers, clinical researchers, doctors, and other interested readers on some of the latest developments in biofilms. 2024-03-07T17:23:43Z 2024-03-07T17:23:43Z 2024 book ONIX_20240307_9781803567099_348 9781803567099 9781803567082 9781803567167 https://directory.doabooks.org/handle/20.500.12854/135439 eng image/jpeg n/a https://www.intechopen.com/books/12720 https://mts.intechopen.com/storage/books/12720/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.108089 10.5772/intechopen.108089 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781803567099 9781803567082 9781803567167 IntechOpen 182 open access
spellingShingle thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
Recent Advances in Bacterial Biofilm Studies
title Recent Advances in Bacterial Biofilm Studies
title_full Recent Advances in Bacterial Biofilm Studies
title_fullStr Recent Advances in Bacterial Biofilm Studies
title_full_unstemmed Recent Advances in Bacterial Biofilm Studies
title_short Recent Advances in Bacterial Biofilm Studies
title_sort recent advances in bacterial biofilm studies
topic thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
topic_facet thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
url ONIX_20240307_9781803567099_348