Neuroendocrine Tumors: Etiology, Diagnosis, and Therapy

Neuroendocrine neoplasms (NENs) are rare and heterogeneous tumors whose incidence has increased over recent years due to improved disease knowledge and diagnostic tools, particularly endoscopy and nuclear medicine. They frequently arise in the gastro-enteropancreatic (GEP) tract, representing approx...

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יצא לאור: MDPI - Multidisciplinary Digital Publishing Institute 2024
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גישה מקוונת:ONIX_20240514_9783036599595_36
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collection Directory of Open Access Books
description Neuroendocrine neoplasms (NENs) are rare and heterogeneous tumors whose incidence has increased over recent years due to improved disease knowledge and diagnostic tools, particularly endoscopy and nuclear medicine. They frequently arise in the gastro-enteropancreatic (GEP) tract, representing approximately 2% of all malignant tumors of the GEP system. Given their rarity and clinical and biological heterogeneity, there is an urgent need for standardized guidelines for the proper management of these neoplasms, which should always be referred to tertiary referral centers. Novel research strategies are needed to better define diagnostic and therapeutic algorithms, especially for specific subgroups of poorly known tumors, including duodenal NENs and functioning tumors. Cooperation between referral centers and the creation of international disease registries should be encouraged to better understand the biology and natural history of these neoplasms and, consequently, improve their management.
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publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-1374342024-05-14T13:04:26Z Neuroendocrine Tumors: Etiology, Diagnosis, and Therapy Rossi, Roberta Elisa Massironi, Sara neuroendocrine neoplasms neuroendocrine tumors neuroendocrine cancer&nbsp thema EDItEUR::M Medicine and Nursing Neuroendocrine neoplasms (NENs) are rare and heterogeneous tumors whose incidence has increased over recent years due to improved disease knowledge and diagnostic tools, particularly endoscopy and nuclear medicine. They frequently arise in the gastro-enteropancreatic (GEP) tract, representing approximately 2% of all malignant tumors of the GEP system. Given their rarity and clinical and biological heterogeneity, there is an urgent need for standardized guidelines for the proper management of these neoplasms, which should always be referred to tertiary referral centers. Novel research strategies are needed to better define diagnostic and therapeutic algorithms, especially for specific subgroups of poorly known tumors, including duodenal NENs and functioning tumors. Cooperation between referral centers and the creation of international disease registries should be encouraged to better understand the biology and natural history of these neoplasms and, consequently, improve their management. 2024-05-14T13:04:19Z 2024-05-14T13:04:19Z 2024 book ONIX_20240514_9783036599595_36 9783036599595 9783036599601 https://directory.doabooks.org/handle/20.500.12854/137434 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/8588 https://mdpi.com/books/pdfview/book/8588 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-9960-1 10.3390/books978-3-0365-9960-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036599595 9783036599601 152 open access
spellingShingle neuroendocrine neoplasms
neuroendocrine tumors
neuroendocrine cancer&nbsp
thema EDItEUR::M Medicine and Nursing
Neuroendocrine Tumors: Etiology, Diagnosis, and Therapy
title Neuroendocrine Tumors: Etiology, Diagnosis, and Therapy
title_full Neuroendocrine Tumors: Etiology, Diagnosis, and Therapy
title_fullStr Neuroendocrine Tumors: Etiology, Diagnosis, and Therapy
title_full_unstemmed Neuroendocrine Tumors: Etiology, Diagnosis, and Therapy
title_short Neuroendocrine Tumors: Etiology, Diagnosis, and Therapy
title_sort neuroendocrine tumors etiology diagnosis and therapy
topic neuroendocrine neoplasms
neuroendocrine tumors
neuroendocrine cancer&nbsp
thema EDItEUR::M Medicine and Nursing
topic_facet neuroendocrine neoplasms
neuroendocrine tumors
neuroendocrine cancer&nbsp
thema EDItEUR::M Medicine and Nursing
url ONIX_20240514_9783036599595_36