Modern Pharmaceutics for Cardiovascular Diseases

Although various non-pharmaceutical strategies addressed to the primary prevention of cardiovascular diseases such as tobacco control policies, reducing the consumption of harmful food, and increasing physical activity still represent a key strategy, often they are not sufficient. Moreover, despite...

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collection Directory of Open Access Books
description Although various non-pharmaceutical strategies addressed to the primary prevention of cardiovascular diseases such as tobacco control policies, reducing the consumption of harmful food, and increasing physical activity still represent a key strategy, often they are not sufficient. Moreover, despite the availability of a plethora of pharmaceutic approaches specifically targeting mechanisms involved in cardiovascular diseases over recent years, the burden of these pathologies has only been marginally alleviated. Therefore, new pharmaceutical and non-pharmaceutical strategies are necessary for both primary and secondary prevention to reduce the burden of cardiovascular diseases. The present reprint brings together original and review articles aiming to highlight the advances in the development of modern pharmaceutics for cardiovascular diseases in recent years.
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spelling doab-20.500.12854ir-1374472024-05-14T13:07:13Z Modern Pharmaceutics for Cardiovascular Diseases Tudorancea, Ionut Iliescu, Radu aspirin coronary artery disease prevention gastric protection micronization collagen cogrinding arterial hypertension HTN nuclear factor erythroid factor 2-related factor 2 Nrf2 oxidative stress antioxidant atherosclerosis pharmacotherapy emergent therapeutics natural anti-atherosclerotic products lipids lipoproteins small dense LDL cholesterol prevention therapy inflammation colchicine NLRP3 inflammasome coronary artery disease acute coronary syndrome heart failure contractility calcium cardiomyocyte myofilament HDAC inhibitor antifibrotic strategies cardiac fibrosis cardiovascular diseases fibrosis pathways therapeutic strategies regenerative medicine cell-free secretomes paracrine factors single-cell RNA sequencing serine protease inhibitor endothelial barrier renin-angiotensin-aldosterone system RAAS angiotensin-converting enzyme-2 ACE2 angiotensin 1-7 Ang (1-7) COVID-19 long-term effects angiotensin receptor–neprilysin inhibitor sodium-glucose co-transporter-2 inhibitors soluble guanylate cyclase activator cardiac myosin activation autonomic modulation SGLT2i empagliflozin NHE1 NHE11 sodium channel thema EDItEUR::M Medicine and Nursing Although various non-pharmaceutical strategies addressed to the primary prevention of cardiovascular diseases such as tobacco control policies, reducing the consumption of harmful food, and increasing physical activity still represent a key strategy, often they are not sufficient. Moreover, despite the availability of a plethora of pharmaceutic approaches specifically targeting mechanisms involved in cardiovascular diseases over recent years, the burden of these pathologies has only been marginally alleviated. Therefore, new pharmaceutical and non-pharmaceutical strategies are necessary for both primary and secondary prevention to reduce the burden of cardiovascular diseases. The present reprint brings together original and review articles aiming to highlight the advances in the development of modern pharmaceutics for cardiovascular diseases in recent years. 2024-05-14T13:07:04Z 2024-05-14T13:07:04Z 2024 book ONIX_20240514_9783036599809_49 9783036599809 9783036599793 https://directory.doabooks.org/handle/20.500.12854/137447 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/8601 https://mdpi.com/books/pdfview/book/8601 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-9979-3 10.3390/books978-3-0365-9979-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036599809 9783036599793 226 open access
spellingShingle aspirin
coronary artery disease prevention
gastric protection
micronization
collagen cogrinding
arterial hypertension
HTN
nuclear factor erythroid factor 2-related factor 2
Nrf2
oxidative stress
antioxidant
atherosclerosis
pharmacotherapy
emergent therapeutics
natural anti-atherosclerotic products
lipids
lipoproteins
small dense LDL
cholesterol
prevention
therapy
inflammation
colchicine
NLRP3 inflammasome
coronary artery disease
acute coronary syndrome
heart failure
contractility
calcium
cardiomyocyte
myofilament
HDAC inhibitor
antifibrotic strategies
cardiac fibrosis
cardiovascular diseases
fibrosis pathways
therapeutic strategies
regenerative medicine
cell-free secretomes
paracrine factors
single-cell RNA sequencing
serine protease inhibitor
endothelial barrier
renin-angiotensin-aldosterone system
RAAS
angiotensin-converting enzyme-2
ACE2
angiotensin 1-7
Ang (1-7)
COVID-19
long-term effects
angiotensin receptor–neprilysin inhibitor
sodium-glucose co-transporter-2 inhibitors
soluble guanylate cyclase activator
cardiac myosin activation
autonomic modulation
SGLT2i
empagliflozin
NHE1
NHE11
sodium channel
thema EDItEUR::M Medicine and Nursing
Modern Pharmaceutics for Cardiovascular Diseases
title Modern Pharmaceutics for Cardiovascular Diseases
title_full Modern Pharmaceutics for Cardiovascular Diseases
title_fullStr Modern Pharmaceutics for Cardiovascular Diseases
title_full_unstemmed Modern Pharmaceutics for Cardiovascular Diseases
title_short Modern Pharmaceutics for Cardiovascular Diseases
title_sort modern pharmaceutics for cardiovascular diseases
topic aspirin
coronary artery disease prevention
gastric protection
micronization
collagen cogrinding
arterial hypertension
HTN
nuclear factor erythroid factor 2-related factor 2
Nrf2
oxidative stress
antioxidant
atherosclerosis
pharmacotherapy
emergent therapeutics
natural anti-atherosclerotic products
lipids
lipoproteins
small dense LDL
cholesterol
prevention
therapy
inflammation
colchicine
NLRP3 inflammasome
coronary artery disease
acute coronary syndrome
heart failure
contractility
calcium
cardiomyocyte
myofilament
HDAC inhibitor
antifibrotic strategies
cardiac fibrosis
cardiovascular diseases
fibrosis pathways
therapeutic strategies
regenerative medicine
cell-free secretomes
paracrine factors
single-cell RNA sequencing
serine protease inhibitor
endothelial barrier
renin-angiotensin-aldosterone system
RAAS
angiotensin-converting enzyme-2
ACE2
angiotensin 1-7
Ang (1-7)
COVID-19
long-term effects
angiotensin receptor–neprilysin inhibitor
sodium-glucose co-transporter-2 inhibitors
soluble guanylate cyclase activator
cardiac myosin activation
autonomic modulation
SGLT2i
empagliflozin
NHE1
NHE11
sodium channel
thema EDItEUR::M Medicine and Nursing
topic_facet aspirin
coronary artery disease prevention
gastric protection
micronization
collagen cogrinding
arterial hypertension
HTN
nuclear factor erythroid factor 2-related factor 2
Nrf2
oxidative stress
antioxidant
atherosclerosis
pharmacotherapy
emergent therapeutics
natural anti-atherosclerotic products
lipids
lipoproteins
small dense LDL
cholesterol
prevention
therapy
inflammation
colchicine
NLRP3 inflammasome
coronary artery disease
acute coronary syndrome
heart failure
contractility
calcium
cardiomyocyte
myofilament
HDAC inhibitor
antifibrotic strategies
cardiac fibrosis
cardiovascular diseases
fibrosis pathways
therapeutic strategies
regenerative medicine
cell-free secretomes
paracrine factors
single-cell RNA sequencing
serine protease inhibitor
endothelial barrier
renin-angiotensin-aldosterone system
RAAS
angiotensin-converting enzyme-2
ACE2
angiotensin 1-7
Ang (1-7)
COVID-19
long-term effects
angiotensin receptor–neprilysin inhibitor
sodium-glucose co-transporter-2 inhibitors
soluble guanylate cyclase activator
cardiac myosin activation
autonomic modulation
SGLT2i
empagliflozin
NHE1
NHE11
sodium channel
thema EDItEUR::M Medicine and Nursing
url ONIX_20240514_9783036599809_49