Past, Present, and Future of Radiochemical Synthesis

The purpose of this Special Issue was to host research and review papers on the past, present, and future of radiochemical synthesis. The Special Issue contains nine original research papers and two reviews within the area of radiochemistry. These address how and why a certain radioactive compound h...

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collection Directory of Open Access Books
description The purpose of this Special Issue was to host research and review papers on the past, present, and future of radiochemical synthesis. The Special Issue contains nine original research papers and two reviews within the area of radiochemistry. These address how and why a certain radioactive compound has been prepared, how a radioactive compound has taken our understanding of a biological system to a different level, how a radiopharmaceutical can be used for treatment, and/or how a radioactive compound has improved our understanding of a certain drug (binding pattern and/or metabolization of the drug).
format Online
id doab-20.500.12854ir-137477
institution Directory of Open Access Books
language eng
publishDate 2024
publishDateRange 2024
publishDateSort 2024
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
record_format ojs
spelling doab-20.500.12854ir-1374772024-05-14T13:13:10Z Past, Present, and Future of Radiochemical Synthesis Borup Jensen, Svend fluorine-18 fluorination on Sep-Pak [18F]FFNP [18F]FDHT mass spectrometry molar activity radiolabeling bioorthogonal reaction click chemistry site-specific reaction radiopharmaceuticals radioisotopes molecular imaging radiochemistry late-stage radiofluorination drug development copper-catalyzed boronic pinacol ester Huntington’s disease mutant huntingtin Positron Emission Tomography carbon-11 [11C]raclopride [18F]MNI-659 peptide transporters positron emission tomography radiotracer fluorination ProTides radiolabelling PET imaging [18F]FPEB mGluR5 positron emission tomography (PET) iodonium-ylide Alzheimer’s Disease (AD) titanium-45 PSMA PET gastrin-releasing peptide receptor targeting [99mTc]Tc-radiotracer tumor targeting [99mTc]Tc-DB1 mimic PEGx-spacer neprilysin-inhibition phosphoramidon radiolabeled somatostatin analogs SST2 SST5 Lu-177 targeted radionuclide therapy neuroendocrine tumors dual-tumor mouse model osteomyelitis animal experimentation pigs PET/CT [18F]FDG [18F]NaF [68Ga]Ga-DOTA-K-A9 [68Ga]Ga-DOTA-GSGK-A11 [68Ga]Ga-DOTA-Siglec-9 [68Ga]Ga-ubiquicidin thema EDItEUR::P Mathematics and Science::PN Chemistry::PNK Inorganic chemistry The purpose of this Special Issue was to host research and review papers on the past, present, and future of radiochemical synthesis. The Special Issue contains nine original research papers and two reviews within the area of radiochemistry. These address how and why a certain radioactive compound has been prepared, how a radioactive compound has taken our understanding of a biological system to a different level, how a radiopharmaceutical can be used for treatment, and/or how a radioactive compound has improved our understanding of a certain drug (binding pattern and/or metabolization of the drug). 2024-05-14T13:12:52Z 2024-05-14T13:12:52Z 2024 book ONIX_20240514_9783039286140_79 9783039286140 9783039286133 https://directory.doabooks.org/handle/20.500.12854/137477 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/8634 https://mdpi.com/books/pdfview/book/8634 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03928-613-3 10.3390/books978-3-03928-613-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039286140 9783039286133 184 open access
spellingShingle fluorine-18
fluorination on Sep-Pak
[18F]FFNP
[18F]FDHT
mass spectrometry
molar activity
radiolabeling
bioorthogonal reaction
click chemistry
site-specific reaction
radiopharmaceuticals
radioisotopes
molecular imaging
radiochemistry
late-stage radiofluorination
drug development
copper-catalyzed
boronic pinacol ester
Huntington’s disease
mutant huntingtin
Positron Emission Tomography
carbon-11
[11C]raclopride
[18F]MNI-659
peptide transporters
positron emission tomography
radiotracer
fluorination
ProTides
radiolabelling
PET imaging
[18F]FPEB
mGluR5
positron emission tomography (PET)
iodonium-ylide
Alzheimer’s Disease (AD)
titanium-45
PSMA
PET
gastrin-releasing peptide receptor targeting
[99mTc]Tc-radiotracer
tumor targeting
[99mTc]Tc-DB1 mimic
PEGx-spacer
neprilysin-inhibition
phosphoramidon
radiolabeled somatostatin analogs
SST2
SST5
Lu-177
targeted radionuclide therapy
neuroendocrine tumors
dual-tumor mouse model
osteomyelitis
animal experimentation
pigs
PET/CT
[18F]FDG
[18F]NaF
[68Ga]Ga-DOTA-K-A9
[68Ga]Ga-DOTA-GSGK-A11 [68Ga]Ga-DOTA-Siglec-9
[68Ga]Ga-ubiquicidin
thema EDItEUR::P Mathematics and Science::PN Chemistry::PNK Inorganic chemistry
Past, Present, and Future of Radiochemical Synthesis
title Past, Present, and Future of Radiochemical Synthesis
title_full Past, Present, and Future of Radiochemical Synthesis
title_fullStr Past, Present, and Future of Radiochemical Synthesis
title_full_unstemmed Past, Present, and Future of Radiochemical Synthesis
title_short Past, Present, and Future of Radiochemical Synthesis
title_sort past present and future of radiochemical synthesis
topic fluorine-18
fluorination on Sep-Pak
[18F]FFNP
[18F]FDHT
mass spectrometry
molar activity
radiolabeling
bioorthogonal reaction
click chemistry
site-specific reaction
radiopharmaceuticals
radioisotopes
molecular imaging
radiochemistry
late-stage radiofluorination
drug development
copper-catalyzed
boronic pinacol ester
Huntington’s disease
mutant huntingtin
Positron Emission Tomography
carbon-11
[11C]raclopride
[18F]MNI-659
peptide transporters
positron emission tomography
radiotracer
fluorination
ProTides
radiolabelling
PET imaging
[18F]FPEB
mGluR5
positron emission tomography (PET)
iodonium-ylide
Alzheimer’s Disease (AD)
titanium-45
PSMA
PET
gastrin-releasing peptide receptor targeting
[99mTc]Tc-radiotracer
tumor targeting
[99mTc]Tc-DB1 mimic
PEGx-spacer
neprilysin-inhibition
phosphoramidon
radiolabeled somatostatin analogs
SST2
SST5
Lu-177
targeted radionuclide therapy
neuroendocrine tumors
dual-tumor mouse model
osteomyelitis
animal experimentation
pigs
PET/CT
[18F]FDG
[18F]NaF
[68Ga]Ga-DOTA-K-A9
[68Ga]Ga-DOTA-GSGK-A11 [68Ga]Ga-DOTA-Siglec-9
[68Ga]Ga-ubiquicidin
thema EDItEUR::P Mathematics and Science::PN Chemistry::PNK Inorganic chemistry
topic_facet fluorine-18
fluorination on Sep-Pak
[18F]FFNP
[18F]FDHT
mass spectrometry
molar activity
radiolabeling
bioorthogonal reaction
click chemistry
site-specific reaction
radiopharmaceuticals
radioisotopes
molecular imaging
radiochemistry
late-stage radiofluorination
drug development
copper-catalyzed
boronic pinacol ester
Huntington’s disease
mutant huntingtin
Positron Emission Tomography
carbon-11
[11C]raclopride
[18F]MNI-659
peptide transporters
positron emission tomography
radiotracer
fluorination
ProTides
radiolabelling
PET imaging
[18F]FPEB
mGluR5
positron emission tomography (PET)
iodonium-ylide
Alzheimer’s Disease (AD)
titanium-45
PSMA
PET
gastrin-releasing peptide receptor targeting
[99mTc]Tc-radiotracer
tumor targeting
[99mTc]Tc-DB1 mimic
PEGx-spacer
neprilysin-inhibition
phosphoramidon
radiolabeled somatostatin analogs
SST2
SST5
Lu-177
targeted radionuclide therapy
neuroendocrine tumors
dual-tumor mouse model
osteomyelitis
animal experimentation
pigs
PET/CT
[18F]FDG
[18F]NaF
[68Ga]Ga-DOTA-K-A9
[68Ga]Ga-DOTA-GSGK-A11 [68Ga]Ga-DOTA-Siglec-9
[68Ga]Ga-ubiquicidin
thema EDItEUR::P Mathematics and Science::PN Chemistry::PNK Inorganic chemistry
url ONIX_20240514_9783039286140_79