Non-motor Disorders in Parkinson Disease: Basic Science and Advances in Treatment

Parkinson’s disease (PD) is the second most common neurodegenerative disorder, and although it is usually considered as a disorder that only affects movement, a broad spectrum of non-motor symptoms (NMSs) can be observed in PD patients. Although the realities of the disease vary enormously from pati...

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description Parkinson’s disease (PD) is the second most common neurodegenerative disorder, and although it is usually considered as a disorder that only affects movement, a broad spectrum of non-motor symptoms (NMSs) can be observed in PD patients. Although the realities of the disease vary enormously from patient to patient, almost all of them have one or more NMS. In fact, a wide range of behavioural, neuropsychiatric, and physical symptoms frequently play a primary role in managing the disorder and constitute a major disease burden for patients and caregivers. The current reprint includes a compilation of published articles about NMSs in Parkinson’s disease and potential treatment strategies.
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institution Directory of Open Access Books
language eng
publishDate 2024
publishDateRange 2024
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publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-1375842024-05-14T13:38:20Z Non-motor Disorders in Parkinson Disease: Basic Science and Advances in Treatment Martinez-Sanchez, Patricia Nieto-Escamez, Francisco transcranial sonography Parkinson’s disease non-motor symptoms systematic review depression apathy autonomic dysfunction bladder dysfunction restless legs syndrome sleep disorders cognitive disorders dementia hallucinations Parkinson disease gastroparesis alpha-synuclein vagus nerve rehabilitation VR virtual reality non-immersive risk of falls balance zonisamide microglia inflammation mitochondria neurodegenerative disease major depressive disorder effectiveness open-label study opicapone anti-social aggressivity counterclockwise rotation zebrafish Danio rerio rotenone neuropsychiatry non-motor subtyping vascular parkinsonism treatment therapy levodopa vitamin D repetitive transcranial magnetic stimulation intracerebral transcatheter laser photobiomodulation Braak’s stages drugs visual impairment visuoperceptive deficit visuospatial deficit visual hallucinations dopamine n/a thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology::MKGW Psychopharmacology Parkinson’s disease (PD) is the second most common neurodegenerative disorder, and although it is usually considered as a disorder that only affects movement, a broad spectrum of non-motor symptoms (NMSs) can be observed in PD patients. Although the realities of the disease vary enormously from patient to patient, almost all of them have one or more NMS. In fact, a wide range of behavioural, neuropsychiatric, and physical symptoms frequently play a primary role in managing the disorder and constitute a major disease burden for patients and caregivers. The current reprint includes a compilation of published articles about NMSs in Parkinson’s disease and potential treatment strategies. 2024-05-14T13:38:12Z 2024-05-14T13:38:12Z 2024 book ONIX_20240514_9783725800049_184 9783725800049 9783725800032 https://directory.doabooks.org/handle/20.500.12854/137584 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/8769 https://mdpi.com/books/pdfview/book/8769 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-0003-2 10.3390/books978-3-7258-0003-2 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725800049 9783725800032 180 open access
spellingShingle transcranial sonography
Parkinson’s disease
non-motor symptoms
systematic review
depression
apathy
autonomic dysfunction
bladder dysfunction
restless legs syndrome
sleep disorders
cognitive disorders
dementia
hallucinations
Parkinson disease
gastroparesis
alpha-synuclein
vagus nerve
rehabilitation
VR
virtual reality
non-immersive
risk of falls
balance
zonisamide
microglia
inflammation
mitochondria
neurodegenerative disease
major depressive disorder
effectiveness
open-label study
opicapone
anti-social
aggressivity
counterclockwise rotation
zebrafish
Danio rerio
rotenone
neuropsychiatry
non-motor subtyping
vascular parkinsonism
treatment
therapy
levodopa
vitamin D
repetitive transcranial magnetic stimulation
intracerebral transcatheter laser photobiomodulation
Braak’s stages
drugs
visual impairment
visuoperceptive deficit
visuospatial deficit
visual hallucinations
dopamine
n/a
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology::MKGW Psychopharmacology
Non-motor Disorders in Parkinson Disease: Basic Science and Advances in Treatment
title Non-motor Disorders in Parkinson Disease: Basic Science and Advances in Treatment
title_full Non-motor Disorders in Parkinson Disease: Basic Science and Advances in Treatment
title_fullStr Non-motor Disorders in Parkinson Disease: Basic Science and Advances in Treatment
title_full_unstemmed Non-motor Disorders in Parkinson Disease: Basic Science and Advances in Treatment
title_short Non-motor Disorders in Parkinson Disease: Basic Science and Advances in Treatment
title_sort non motor disorders in parkinson disease basic science and advances in treatment
topic transcranial sonography
Parkinson’s disease
non-motor symptoms
systematic review
depression
apathy
autonomic dysfunction
bladder dysfunction
restless legs syndrome
sleep disorders
cognitive disorders
dementia
hallucinations
Parkinson disease
gastroparesis
alpha-synuclein
vagus nerve
rehabilitation
VR
virtual reality
non-immersive
risk of falls
balance
zonisamide
microglia
inflammation
mitochondria
neurodegenerative disease
major depressive disorder
effectiveness
open-label study
opicapone
anti-social
aggressivity
counterclockwise rotation
zebrafish
Danio rerio
rotenone
neuropsychiatry
non-motor subtyping
vascular parkinsonism
treatment
therapy
levodopa
vitamin D
repetitive transcranial magnetic stimulation
intracerebral transcatheter laser photobiomodulation
Braak’s stages
drugs
visual impairment
visuoperceptive deficit
visuospatial deficit
visual hallucinations
dopamine
n/a
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology::MKGW Psychopharmacology
topic_facet transcranial sonography
Parkinson’s disease
non-motor symptoms
systematic review
depression
apathy
autonomic dysfunction
bladder dysfunction
restless legs syndrome
sleep disorders
cognitive disorders
dementia
hallucinations
Parkinson disease
gastroparesis
alpha-synuclein
vagus nerve
rehabilitation
VR
virtual reality
non-immersive
risk of falls
balance
zonisamide
microglia
inflammation
mitochondria
neurodegenerative disease
major depressive disorder
effectiveness
open-label study
opicapone
anti-social
aggressivity
counterclockwise rotation
zebrafish
Danio rerio
rotenone
neuropsychiatry
non-motor subtyping
vascular parkinsonism
treatment
therapy
levodopa
vitamin D
repetitive transcranial magnetic stimulation
intracerebral transcatheter laser photobiomodulation
Braak’s stages
drugs
visual impairment
visuoperceptive deficit
visuospatial deficit
visual hallucinations
dopamine
n/a
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology::MKGW Psychopharmacology
url ONIX_20240514_9783725800049_184