Key Advances in the Treatment of the Critically Ill

This reprint of a Special Issue of the Journal of Clinical Medicine includes a submission-motivating editorial, eleven clinical research papers (including a meta-analysis), six narrative reviews and a survey-based study, focusing on a wide variety of aspects of intensive care. Five studies pertain...

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Publicado em: MDPI - Multidisciplinary Digital Publishing Institute 2024
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collection Directory of Open Access Books
description This reprint of a Special Issue of the Journal of Clinical Medicine includes a submission-motivating editorial, eleven clinical research papers (including a meta-analysis), six narrative reviews and a survey-based study, focusing on a wide variety of aspects of intensive care. Five studies pertain to coronavirus disease-19 (COVID-19) assess intermittent vs. prolonged prone ventilation and the interaction between early pressure-supported ventilation and kidney injury, as well as the clinical significance of biomarkers (pro-adrenomedullin and heparinase) and of an impaired antibody response. The COVID-19 narrative reviews analyze published evidence on therapeutic interventions in COVID-19-related acute respiratory distress syndrome (ARDS) and invasive fungal infections. The remaining six studies assess the Norwegian version of the Chelsea physical assessment tool, the interaction of base excess and lactate in outcome prediction, left ventricular dysfunction in ARDS, respiratory drive after isoflurane sedation, renal preplacement therapy as a prognostic factor and diaphragmatic dysfunction in severe trauma patients. The remaining four narrative reviews analyze published evidence on immunoglobulins in sepsis, treatments for post-cardiac arrest syndrome, blood purification in sepsis and the management of traumatic brain injury. Lastly, the survey-based study explores the temporal evolution of European resuscitation and end-of-life practices. The Special Issue primarily aims to publish both innovative research findings and comprehensive reviews of existing scientific knowledge on acute and life-threatening disease.
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language eng
publishDate 2024
publishDateRange 2024
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publisher MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-1376792024-05-14T14:06:05Z Key Advances in the Treatment of the Critically Ill Mentzelopoulos, Spyros D. fungal infections critically ill CAPA COVID-19 CAM CAC acute kidney injury chronic kidney disease continuous renal replacement therapy end-stage of kidney disease intermittent hemodialysis mortality renal replacement therapy n/a SARS-CoV-2 critical care antibody response NET histones ethics resuscitation terminal care surveys and questionnaires emergency care proadrenomedullin MR-proADM biomarkers intensive care endothelitis brain trauma intracranial hypertension neuromonitoring acute respiratory distress syndrome mechanical ventilation ARDS endothelial dysfunction heparanase heparan sulfate biomarker anesthesia inhaled sedation respiratory drive isoflurane propofol left ventricular diastolic dysfunction total lung weight base excess alactic base excess hyperlactatemia shock septic shock sepsis mediators hemofiltration hemoadsorption acute kidney injury (AKI) acute respiratory distress syndrome (ARDS) ventilator-induced kidney injury (VIKI) multiple trauma thoracic trauma diaphragmatic muscle diaphragmatic dysfunction ventilator-induced diaphragmatic dysfunction prone position cardiac arrest post-resuscitation care intensive care medicine outcome sepsis immunotherapy physiotherapy physical function early rehabilitation measurement tool critical illness CPAx thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues This reprint of a Special Issue of the Journal of Clinical Medicine includes a submission-motivating editorial, eleven clinical research papers (including a meta-analysis), six narrative reviews and a survey-based study, focusing on a wide variety of aspects of intensive care. Five studies pertain to coronavirus disease-19 (COVID-19) assess intermittent vs. prolonged prone ventilation and the interaction between early pressure-supported ventilation and kidney injury, as well as the clinical significance of biomarkers (pro-adrenomedullin and heparinase) and of an impaired antibody response. The COVID-19 narrative reviews analyze published evidence on therapeutic interventions in COVID-19-related acute respiratory distress syndrome (ARDS) and invasive fungal infections. The remaining six studies assess the Norwegian version of the Chelsea physical assessment tool, the interaction of base excess and lactate in outcome prediction, left ventricular dysfunction in ARDS, respiratory drive after isoflurane sedation, renal preplacement therapy as a prognostic factor and diaphragmatic dysfunction in severe trauma patients. The remaining four narrative reviews analyze published evidence on immunoglobulins in sepsis, treatments for post-cardiac arrest syndrome, blood purification in sepsis and the management of traumatic brain injury. Lastly, the survey-based study explores the temporal evolution of European resuscitation and end-of-life practices. The Special Issue primarily aims to publish both innovative research findings and comprehensive reviews of existing scientific knowledge on acute and life-threatening disease. 2024-05-14T14:06:01Z 2024-05-14T14:06:01Z 2024 book ONIX_20240514_9783725802678_276 9783725802678 9783725802685 https://directory.doabooks.org/handle/20.500.12854/137679 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/8896 https://mdpi.com/books/pdfview/book/8896 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-0268-5 10.3390/books978-3-7258-0268-5 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725802678 9783725802685 260 open access
spellingShingle fungal infections
critically ill
CAPA
COVID-19
CAM
CAC
acute kidney injury
chronic kidney disease
continuous renal replacement therapy
end-stage of kidney disease
intermittent hemodialysis
mortality
renal replacement therapy
n/a
SARS-CoV-2
critical care
antibody response
NET
histones
ethics
resuscitation
terminal care
surveys and questionnaires
emergency care
proadrenomedullin
MR-proADM
biomarkers
intensive care
endothelitis
brain trauma
intracranial hypertension
neuromonitoring
acute respiratory distress syndrome
mechanical ventilation
ARDS
endothelial dysfunction
heparanase
heparan sulfate
biomarker
anesthesia
inhaled sedation
respiratory drive
isoflurane
propofol
left ventricular diastolic dysfunction
total lung weight
base excess
alactic base excess
hyperlactatemia
shock
septic shock
sepsis mediators
hemofiltration
hemoadsorption
acute kidney injury (AKI)
acute respiratory distress syndrome (ARDS)
ventilator-induced kidney injury (VIKI)
multiple trauma
thoracic trauma
diaphragmatic muscle
diaphragmatic dysfunction
ventilator-induced diaphragmatic dysfunction
prone position
cardiac arrest
post-resuscitation care
intensive care medicine
outcome
sepsis
immunotherapy
physiotherapy
physical function
early rehabilitation
measurement tool
critical illness
CPAx
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
Key Advances in the Treatment of the Critically Ill
title Key Advances in the Treatment of the Critically Ill
title_full Key Advances in the Treatment of the Critically Ill
title_fullStr Key Advances in the Treatment of the Critically Ill
title_full_unstemmed Key Advances in the Treatment of the Critically Ill
title_short Key Advances in the Treatment of the Critically Ill
title_sort key advances in the treatment of the critically ill
topic fungal infections
critically ill
CAPA
COVID-19
CAM
CAC
acute kidney injury
chronic kidney disease
continuous renal replacement therapy
end-stage of kidney disease
intermittent hemodialysis
mortality
renal replacement therapy
n/a
SARS-CoV-2
critical care
antibody response
NET
histones
ethics
resuscitation
terminal care
surveys and questionnaires
emergency care
proadrenomedullin
MR-proADM
biomarkers
intensive care
endothelitis
brain trauma
intracranial hypertension
neuromonitoring
acute respiratory distress syndrome
mechanical ventilation
ARDS
endothelial dysfunction
heparanase
heparan sulfate
biomarker
anesthesia
inhaled sedation
respiratory drive
isoflurane
propofol
left ventricular diastolic dysfunction
total lung weight
base excess
alactic base excess
hyperlactatemia
shock
septic shock
sepsis mediators
hemofiltration
hemoadsorption
acute kidney injury (AKI)
acute respiratory distress syndrome (ARDS)
ventilator-induced kidney injury (VIKI)
multiple trauma
thoracic trauma
diaphragmatic muscle
diaphragmatic dysfunction
ventilator-induced diaphragmatic dysfunction
prone position
cardiac arrest
post-resuscitation care
intensive care medicine
outcome
sepsis
immunotherapy
physiotherapy
physical function
early rehabilitation
measurement tool
critical illness
CPAx
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
topic_facet fungal infections
critically ill
CAPA
COVID-19
CAM
CAC
acute kidney injury
chronic kidney disease
continuous renal replacement therapy
end-stage of kidney disease
intermittent hemodialysis
mortality
renal replacement therapy
n/a
SARS-CoV-2
critical care
antibody response
NET
histones
ethics
resuscitation
terminal care
surveys and questionnaires
emergency care
proadrenomedullin
MR-proADM
biomarkers
intensive care
endothelitis
brain trauma
intracranial hypertension
neuromonitoring
acute respiratory distress syndrome
mechanical ventilation
ARDS
endothelial dysfunction
heparanase
heparan sulfate
biomarker
anesthesia
inhaled sedation
respiratory drive
isoflurane
propofol
left ventricular diastolic dysfunction
total lung weight
base excess
alactic base excess
hyperlactatemia
shock
septic shock
sepsis mediators
hemofiltration
hemoadsorption
acute kidney injury (AKI)
acute respiratory distress syndrome (ARDS)
ventilator-induced kidney injury (VIKI)
multiple trauma
thoracic trauma
diaphragmatic muscle
diaphragmatic dysfunction
ventilator-induced diaphragmatic dysfunction
prone position
cardiac arrest
post-resuscitation care
intensive care medicine
outcome
sepsis
immunotherapy
physiotherapy
physical function
early rehabilitation
measurement tool
critical illness
CPAx
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
url ONIX_20240514_9783725802678_276