Research Progress of Plant Compounds for Diabetes and Its Complications
Numerous chronic complications appear in the evolution of diabetes mellitus type 2 and type 1, and they significantly influence the duration of life of the patient. Diabetes mellitus is a metabolic disease where pro-oxidant and pro-inflammatory mechanisms are intensely expressed. Given the numerous...
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MDPI - Multidisciplinary Digital Publishing Institute
2024
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| Online Access: | ONIX_20240514_9783725805006_279 |
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| description | Numerous chronic complications appear in the evolution of diabetes mellitus type 2 and type 1, and they significantly influence the duration of life of the patient. Diabetes mellitus is a metabolic disease where pro-oxidant and pro-inflammatory mechanisms are intensely expressed. Given the numerous beneficial effects present in compounds extracted from different plants, such as reduction in insulin resistance, improvement of endothelial function, improvement of beta-cell function, improvement of lipid metabolism, antioxidant effect, and anti-inflammatory effect, the idea behind this Special Issue is to present significant results from original research or from international data in review articles. It is not only the potential chemical substances extracted form plants that are important, but also the delivery of these substances to target tissues; therefore, the Issu also focuses on modalities to improve the biological effects of these substances, such as nanotechnology. The standardization of these substances and their potential evolution toward drug development is the key concept of this Special Issue, with the ultimate goal to develop new drugs starting from beneficial plant compounds to target the complications of diabetes mellitus at the molecular level. |
| format | Online |
| id | doab-20.500.12854ir-137682 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
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| spelling | doab-20.500.12854ir-1376822024-05-14T14:06:42Z Research Progress of Plant Compounds for Diabetes and Its Complications Vesa, Cosmin Mihai Zaha, Dana Blepharispermum hirtum Asteraceae GS-MS analysis essential oils triple-negative breast cancer α-glucosidase chlorogenic acid diprotin A dipeptidyl peptidase IV molecular dynamics simulations phenolic acids type-2 diabetes mellitus aqua exercise burdock extract metabolic syndrome cardiovascular disease vascular endothelial function anti-inflammatory anti-cancer anti-diabetic luteolin secondary metabolite flavonoid quercetin anti-diabetic activity oxidative stress reno-protective effect anti-inflammatory activity diabetes mellitus M. tenuifolia lipid profile kidney functions cardiac functions acetylcholine endothelium diabetes moderate swimming training aorta hyperglycemic hyperlipidemia lawsone lawsone methyl ether diabetic retinopathy cataracts gold nanoparticles Rutin antioxidant early incipient GLP-1 Ipomoea batatas L. flavonoid pharmacology thema EDItEUR::P Mathematics and Science::PB Mathematics::PBW Applied mathematics Numerous chronic complications appear in the evolution of diabetes mellitus type 2 and type 1, and they significantly influence the duration of life of the patient. Diabetes mellitus is a metabolic disease where pro-oxidant and pro-inflammatory mechanisms are intensely expressed. Given the numerous beneficial effects present in compounds extracted from different plants, such as reduction in insulin resistance, improvement of endothelial function, improvement of beta-cell function, improvement of lipid metabolism, antioxidant effect, and anti-inflammatory effect, the idea behind this Special Issue is to present significant results from original research or from international data in review articles. It is not only the potential chemical substances extracted form plants that are important, but also the delivery of these substances to target tissues; therefore, the Issu also focuses on modalities to improve the biological effects of these substances, such as nanotechnology. The standardization of these substances and their potential evolution toward drug development is the key concept of this Special Issue, with the ultimate goal to develop new drugs starting from beneficial plant compounds to target the complications of diabetes mellitus at the molecular level. 2024-05-14T14:06:37Z 2024-05-14T14:06:37Z 2024 book ONIX_20240514_9783725805006_279 9783725805006 9783725804993 https://directory.doabooks.org/handle/20.500.12854/137682 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/8900 https://mdpi.com/books/pdfview/book/8900 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-0499-3 10.3390/books978-3-7258-0499-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725805006 9783725804993 180 open access |
| spellingShingle | Blepharispermum hirtum Asteraceae GS-MS analysis essential oils triple-negative breast cancer α-glucosidase chlorogenic acid diprotin A dipeptidyl peptidase IV molecular dynamics simulations phenolic acids type-2 diabetes mellitus aqua exercise burdock extract metabolic syndrome cardiovascular disease vascular endothelial function anti-inflammatory anti-cancer anti-diabetic luteolin secondary metabolite flavonoid quercetin anti-diabetic activity oxidative stress reno-protective effect anti-inflammatory activity diabetes mellitus M. tenuifolia lipid profile kidney functions cardiac functions acetylcholine endothelium diabetes moderate swimming training aorta hyperglycemic hyperlipidemia lawsone lawsone methyl ether diabetic retinopathy cataracts gold nanoparticles Rutin antioxidant early incipient GLP-1 Ipomoea batatas L. flavonoid pharmacology thema EDItEUR::P Mathematics and Science::PB Mathematics::PBW Applied mathematics Research Progress of Plant Compounds for Diabetes and Its Complications |
| title | Research Progress of Plant Compounds for Diabetes and Its Complications |
| title_full | Research Progress of Plant Compounds for Diabetes and Its Complications |
| title_fullStr | Research Progress of Plant Compounds for Diabetes and Its Complications |
| title_full_unstemmed | Research Progress of Plant Compounds for Diabetes and Its Complications |
| title_short | Research Progress of Plant Compounds for Diabetes and Its Complications |
| title_sort | research progress of plant compounds for diabetes and its complications |
| topic | Blepharispermum hirtum Asteraceae GS-MS analysis essential oils triple-negative breast cancer α-glucosidase chlorogenic acid diprotin A dipeptidyl peptidase IV molecular dynamics simulations phenolic acids type-2 diabetes mellitus aqua exercise burdock extract metabolic syndrome cardiovascular disease vascular endothelial function anti-inflammatory anti-cancer anti-diabetic luteolin secondary metabolite flavonoid quercetin anti-diabetic activity oxidative stress reno-protective effect anti-inflammatory activity diabetes mellitus M. tenuifolia lipid profile kidney functions cardiac functions acetylcholine endothelium diabetes moderate swimming training aorta hyperglycemic hyperlipidemia lawsone lawsone methyl ether diabetic retinopathy cataracts gold nanoparticles Rutin antioxidant early incipient GLP-1 Ipomoea batatas L. flavonoid pharmacology thema EDItEUR::P Mathematics and Science::PB Mathematics::PBW Applied mathematics |
| topic_facet | Blepharispermum hirtum Asteraceae GS-MS analysis essential oils triple-negative breast cancer α-glucosidase chlorogenic acid diprotin A dipeptidyl peptidase IV molecular dynamics simulations phenolic acids type-2 diabetes mellitus aqua exercise burdock extract metabolic syndrome cardiovascular disease vascular endothelial function anti-inflammatory anti-cancer anti-diabetic luteolin secondary metabolite flavonoid quercetin anti-diabetic activity oxidative stress reno-protective effect anti-inflammatory activity diabetes mellitus M. tenuifolia lipid profile kidney functions cardiac functions acetylcholine endothelium diabetes moderate swimming training aorta hyperglycemic hyperlipidemia lawsone lawsone methyl ether diabetic retinopathy cataracts gold nanoparticles Rutin antioxidant early incipient GLP-1 Ipomoea batatas L. flavonoid pharmacology thema EDItEUR::P Mathematics and Science::PB Mathematics::PBW Applied mathematics |
| url | ONIX_20240514_9783725805006_279 |