New Trends in Diabetes, Hypertension and Cardiovascular Diseases
Cardiovascular disease (CVD) encompasses a range of disorders affecting the heart and blood vessels, including coronary heart disease, cerebrovascular disease, and conditions such as aortic aneurysm and lower extremity peripheral artery disease. It remains the leading cause of death worldwide, claim...
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| Sprog: | engelsk |
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MDPI - Multidisciplinary Digital Publishing Institute
2024
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| Online adgang: | ONIX_20240514_9783725805372_297 |
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| description | Cardiovascular disease (CVD) encompasses a range of disorders affecting the heart and blood vessels, including coronary heart disease, cerebrovascular disease, and conditions such as aortic aneurysm and lower extremity peripheral artery disease. It remains the leading cause of death worldwide, claiming 17.9 million lives annually, despite the availability of numerous therapeutic drugs. Thus, further research is warranted to enhance CVD treatment and reduce its morbidity and mortality.Diabetes and hypertension are conditions commonly found in aging populations that share common pathogenic pathways and are both strong, independent risk factors for CVD. Reducing blood glucose and blood pressure levels can significantly contribute to mitigating CVD-related morbidity and mortality.This Special Issue aims to present the latest perspectives and research findings on diabetes, hypertension, and CVD, comprising one Editorial article, eight review articles, and eight original research articles. These articles provide a comprehensive overview of recent developments in research on hypertension, insulin resistance/diabetes, and CVD, including atherosclerosis, aortic aneurysm, and myocardial infarction. They offer insights into CVD pathogenesis and facilitate the development of new therapeutic approaches. |
| format | Online |
| id | doab-20.500.12854ir-137700 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1377002024-05-14T14:10:08Z New Trends in Diabetes, Hypertension and Cardiovascular Diseases Wang, Yutang Magliano, Dianna gut microbiome atherosclerosis TMAO aging gut dysbiosis probiotics short chain fatty acids oxidative stress obesity cardiovascular disease cardiometabolic diseases coronary artery disease metabolic syndrome type 2 diabetes sex blood pressure hypertension GWAS SNP association Inflammasome NLRP3 IL-1β IL-18 therapeutic target NLRP3 inhibitors ischemic stroke hero heat-resistant obscure chaperones SERPINE1 mRNA binding protein 1 SERBP1 activated partial thromboplastin time body mass index gene-environmental interaction night shift clock genes circadian rhythm ABPM dipping physician internal medicine T2D diabetes carbohydrate metabolism insulin resistance physiologic insulin resensitization (PIR) principle component analysis stress reactivity age-related difference ISIAH rat strain myocardial infarction human inflammation clinical outcomes abdominal aortic aneurysm thoracic aortic aneurysm VSMC phenotypic switching redox signaling RAS ACE inhibitors ARBs MARCKS PKC cathepsin proteolysis kidney Duchenne Muscular Dystrophy fibrosis cardiac remodeling cardiac dysfunction tumor macrophage recruitment nitric oxide synthase endothelial NOS neuronal NOS inducible NOS NOS inhibitor vascular aging genomic instability mouse models vessels-on-a-chip hydralazine n/a thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues Cardiovascular disease (CVD) encompasses a range of disorders affecting the heart and blood vessels, including coronary heart disease, cerebrovascular disease, and conditions such as aortic aneurysm and lower extremity peripheral artery disease. It remains the leading cause of death worldwide, claiming 17.9 million lives annually, despite the availability of numerous therapeutic drugs. Thus, further research is warranted to enhance CVD treatment and reduce its morbidity and mortality.Diabetes and hypertension are conditions commonly found in aging populations that share common pathogenic pathways and are both strong, independent risk factors for CVD. Reducing blood glucose and blood pressure levels can significantly contribute to mitigating CVD-related morbidity and mortality.This Special Issue aims to present the latest perspectives and research findings on diabetes, hypertension, and CVD, comprising one Editorial article, eight review articles, and eight original research articles. These articles provide a comprehensive overview of recent developments in research on hypertension, insulin resistance/diabetes, and CVD, including atherosclerosis, aortic aneurysm, and myocardial infarction. They offer insights into CVD pathogenesis and facilitate the development of new therapeutic approaches. 2024-05-14T14:09:59Z 2024-05-14T14:09:59Z 2024 book ONIX_20240514_9783725805372_297 9783725805372 9783725805389 https://directory.doabooks.org/handle/20.500.12854/137700 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/8923 https://mdpi.com/books/pdfview/book/8923 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-0538-9 10.3390/books978-3-7258-0538-9 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725805372 9783725805389 310 open access |
| spellingShingle | gut microbiome atherosclerosis TMAO aging gut dysbiosis probiotics short chain fatty acids oxidative stress obesity cardiovascular disease cardiometabolic diseases coronary artery disease metabolic syndrome type 2 diabetes sex blood pressure hypertension GWAS SNP association Inflammasome NLRP3 IL-1β IL-18 therapeutic target NLRP3 inhibitors ischemic stroke hero heat-resistant obscure chaperones SERPINE1 mRNA binding protein 1 SERBP1 activated partial thromboplastin time body mass index gene-environmental interaction night shift clock genes circadian rhythm ABPM dipping physician internal medicine T2D diabetes carbohydrate metabolism insulin resistance physiologic insulin resensitization (PIR) principle component analysis stress reactivity age-related difference ISIAH rat strain myocardial infarction human inflammation clinical outcomes abdominal aortic aneurysm thoracic aortic aneurysm VSMC phenotypic switching redox signaling RAS ACE inhibitors ARBs MARCKS PKC cathepsin proteolysis kidney Duchenne Muscular Dystrophy fibrosis cardiac remodeling cardiac dysfunction tumor macrophage recruitment nitric oxide synthase endothelial NOS neuronal NOS inducible NOS NOS inhibitor vascular aging genomic instability mouse models vessels-on-a-chip hydralazine n/a thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues New Trends in Diabetes, Hypertension and Cardiovascular Diseases |
| title | New Trends in Diabetes, Hypertension and Cardiovascular Diseases |
| title_full | New Trends in Diabetes, Hypertension and Cardiovascular Diseases |
| title_fullStr | New Trends in Diabetes, Hypertension and Cardiovascular Diseases |
| title_full_unstemmed | New Trends in Diabetes, Hypertension and Cardiovascular Diseases |
| title_short | New Trends in Diabetes, Hypertension and Cardiovascular Diseases |
| title_sort | new trends in diabetes hypertension and cardiovascular diseases |
| topic | gut microbiome atherosclerosis TMAO aging gut dysbiosis probiotics short chain fatty acids oxidative stress obesity cardiovascular disease cardiometabolic diseases coronary artery disease metabolic syndrome type 2 diabetes sex blood pressure hypertension GWAS SNP association Inflammasome NLRP3 IL-1β IL-18 therapeutic target NLRP3 inhibitors ischemic stroke hero heat-resistant obscure chaperones SERPINE1 mRNA binding protein 1 SERBP1 activated partial thromboplastin time body mass index gene-environmental interaction night shift clock genes circadian rhythm ABPM dipping physician internal medicine T2D diabetes carbohydrate metabolism insulin resistance physiologic insulin resensitization (PIR) principle component analysis stress reactivity age-related difference ISIAH rat strain myocardial infarction human inflammation clinical outcomes abdominal aortic aneurysm thoracic aortic aneurysm VSMC phenotypic switching redox signaling RAS ACE inhibitors ARBs MARCKS PKC cathepsin proteolysis kidney Duchenne Muscular Dystrophy fibrosis cardiac remodeling cardiac dysfunction tumor macrophage recruitment nitric oxide synthase endothelial NOS neuronal NOS inducible NOS NOS inhibitor vascular aging genomic instability mouse models vessels-on-a-chip hydralazine n/a thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues |
| topic_facet | gut microbiome atherosclerosis TMAO aging gut dysbiosis probiotics short chain fatty acids oxidative stress obesity cardiovascular disease cardiometabolic diseases coronary artery disease metabolic syndrome type 2 diabetes sex blood pressure hypertension GWAS SNP association Inflammasome NLRP3 IL-1β IL-18 therapeutic target NLRP3 inhibitors ischemic stroke hero heat-resistant obscure chaperones SERPINE1 mRNA binding protein 1 SERBP1 activated partial thromboplastin time body mass index gene-environmental interaction night shift clock genes circadian rhythm ABPM dipping physician internal medicine T2D diabetes carbohydrate metabolism insulin resistance physiologic insulin resensitization (PIR) principle component analysis stress reactivity age-related difference ISIAH rat strain myocardial infarction human inflammation clinical outcomes abdominal aortic aneurysm thoracic aortic aneurysm VSMC phenotypic switching redox signaling RAS ACE inhibitors ARBs MARCKS PKC cathepsin proteolysis kidney Duchenne Muscular Dystrophy fibrosis cardiac remodeling cardiac dysfunction tumor macrophage recruitment nitric oxide synthase endothelial NOS neuronal NOS inducible NOS NOS inhibitor vascular aging genomic instability mouse models vessels-on-a-chip hydralazine n/a thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues |
| url | ONIX_20240514_9783725805372_297 |