Novel Viral Vectors for Gene Therapy 2023

Viral vectors are gene transfer tools assembled from the backbones of naturally occurring viruses. These replication-incompetent vehicles transfer assigned payloads into eukaryotic cells. Numerous viral vector systems that influence cells or tissues have been used to perform basic and preclinical re...

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Julkaistu: MDPI - Multidisciplinary Digital Publishing Institute 2024
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collection Directory of Open Access Books
description Viral vectors are gene transfer tools assembled from the backbones of naturally occurring viruses. These replication-incompetent vehicles transfer assigned payloads into eukaryotic cells. Numerous viral vector systems that influence cells or tissues have been used to perform basic and preclinical research. Some virus-derived vectors found their way into clinical practice.
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institution Directory of Open Access Books
language eng
publishDate 2024
publishDateRange 2024
publishDateSort 2024
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
record_format ojs
spelling doab-20.500.12854ir-1377512024-05-14T14:20:51Z Novel Viral Vectors for Gene Therapy 2023 Herchenröder, Ottmar Pützer, Brigitte sickle cell disease thalassemia globin gene therapy γ-globin lentiviral vector HbF HPFH enhancers -117 HPFH type CD34+ hematopoietic stem cells viral vector gene therapy cancer chronic disease vaccines preclinical models clinical trials approved drugs brain tumour oncolytic virus receptor therapy AAV8 VLP nES GEMMA DMA cryo-TEM reovirus oncolytic viral therapy Ras pathway chemotherapy stemness pluripotency cytolysis reprogramming innate immune adeno-associated virus lentivirus adenovirus adenovirus vector replication-competent adenovirus limiting dilution animal-origin-free culture media vaccine SARS-CoV-2 spike protein genetically modified organisms (GMOs) viral vectors virucidal activity suspension tests virus inactivation disinfection AAV vector adeno-associated virus (AAV) novel serotype porcine capsid bovine capsid luciferase imaging transduction n/a thema EDItEUR::U Computing and Information Technology::UY Computer science Viral vectors are gene transfer tools assembled from the backbones of naturally occurring viruses. These replication-incompetent vehicles transfer assigned payloads into eukaryotic cells. Numerous viral vector systems that influence cells or tissues have been used to perform basic and preclinical research. Some virus-derived vectors found their way into clinical practice. 2024-05-14T14:20:47Z 2024-05-14T14:20:47Z 2024 book ONIX_20240514_9783725805303_347 9783725805303 9783725805297 https://directory.doabooks.org/handle/20.500.12854/137751 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/8984 https://mdpi.com/books/pdfview/book/8984 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-0529-7 10.3390/books978-3-7258-0529-7 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725805303 9783725805297 214 open access
spellingShingle sickle cell disease
thalassemia
globin gene therapy
γ-globin lentiviral vector
HbF
HPFH enhancers
-117 HPFH type
CD34+ hematopoietic stem cells
viral vector
gene therapy
cancer
chronic disease
vaccines
preclinical models
clinical trials
approved drugs
brain tumour
oncolytic virus
receptor
therapy
AAV8
VLP
nES GEMMA
DMA
cryo-TEM
reovirus
oncolytic viral therapy
Ras pathway
chemotherapy
stemness
pluripotency
cytolysis
reprogramming
innate immune
adeno-associated virus
lentivirus
adenovirus
adenovirus vector
replication-competent adenovirus
limiting dilution
animal-origin-free culture media
vaccine
SARS-CoV-2
spike protein
genetically modified organisms (GMOs)
viral vectors
virucidal activity
suspension tests
virus inactivation
disinfection
AAV
vector
adeno-associated virus (AAV)
novel serotype
porcine capsid
bovine capsid
luciferase imaging
transduction
n/a
thema EDItEUR::U Computing and Information Technology::UY Computer science
Novel Viral Vectors for Gene Therapy 2023
title Novel Viral Vectors for Gene Therapy 2023
title_full Novel Viral Vectors for Gene Therapy 2023
title_fullStr Novel Viral Vectors for Gene Therapy 2023
title_full_unstemmed Novel Viral Vectors for Gene Therapy 2023
title_short Novel Viral Vectors for Gene Therapy 2023
title_sort novel viral vectors for gene therapy 2023
topic sickle cell disease
thalassemia
globin gene therapy
γ-globin lentiviral vector
HbF
HPFH enhancers
-117 HPFH type
CD34+ hematopoietic stem cells
viral vector
gene therapy
cancer
chronic disease
vaccines
preclinical models
clinical trials
approved drugs
brain tumour
oncolytic virus
receptor
therapy
AAV8
VLP
nES GEMMA
DMA
cryo-TEM
reovirus
oncolytic viral therapy
Ras pathway
chemotherapy
stemness
pluripotency
cytolysis
reprogramming
innate immune
adeno-associated virus
lentivirus
adenovirus
adenovirus vector
replication-competent adenovirus
limiting dilution
animal-origin-free culture media
vaccine
SARS-CoV-2
spike protein
genetically modified organisms (GMOs)
viral vectors
virucidal activity
suspension tests
virus inactivation
disinfection
AAV
vector
adeno-associated virus (AAV)
novel serotype
porcine capsid
bovine capsid
luciferase imaging
transduction
n/a
thema EDItEUR::U Computing and Information Technology::UY Computer science
topic_facet sickle cell disease
thalassemia
globin gene therapy
γ-globin lentiviral vector
HbF
HPFH enhancers
-117 HPFH type
CD34+ hematopoietic stem cells
viral vector
gene therapy
cancer
chronic disease
vaccines
preclinical models
clinical trials
approved drugs
brain tumour
oncolytic virus
receptor
therapy
AAV8
VLP
nES GEMMA
DMA
cryo-TEM
reovirus
oncolytic viral therapy
Ras pathway
chemotherapy
stemness
pluripotency
cytolysis
reprogramming
innate immune
adeno-associated virus
lentivirus
adenovirus
adenovirus vector
replication-competent adenovirus
limiting dilution
animal-origin-free culture media
vaccine
SARS-CoV-2
spike protein
genetically modified organisms (GMOs)
viral vectors
virucidal activity
suspension tests
virus inactivation
disinfection
AAV
vector
adeno-associated virus (AAV)
novel serotype
porcine capsid
bovine capsid
luciferase imaging
transduction
n/a
thema EDItEUR::U Computing and Information Technology::UY Computer science
url ONIX_20240514_9783725805303_347