Physiology and Pathophysiology of Placenta
Dear colleagues, The development and differentiation of placental villous trees are two key processes tightly regulated during pregnancy. In fact, several growth factors, their receptors and other types of molecules can regulate placental cell proliferation, differentiation, migration and invasion....
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| 格式: | Online |
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| 語言: | 英语 |
| 出版: |
MDPI - Multidisciplinary Digital Publishing Institute
2024
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| 在線閱讀: | ONIX_20240514_9783725807925_437 |
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沒有標簽, 成為第一個標記此記錄!
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| _version_ | 1869527814841040896 |
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| collection | Directory of Open Access Books |
| description | Dear colleagues, The development and differentiation of placental villous trees are two key processes tightly regulated during pregnancy. In fact, several growth factors, their receptors and other types of molecules can regulate placental cell proliferation, differentiation, migration and invasion. Thus, an impairment of normal placental development can lead to a series of pregnancy pathologies, i.e., preeclampsia (PE), fetal growth restriction (FGR), gestational trophoblastic diseases (GTD) and gestational diabetes mellitus (GDM). Furthermore, external factors, such as microbial agents, chemicals and natural compounds, can affect placental development and function, impairing pregnancy outcomes. These pregnancy complications result in increased maternal and fetal mortality and morbidity, leading to life-long health implications in both mother and child. The aim of this Special Issue is to provide an overview of placental development and pathophysiology in order to better understand the molecular mechanisms involved in pregnancy. |
| format | Online |
| id | doab-20.500.12854ir-137841 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1378412024-05-14T14:40:58Z Physiology and Pathophysiology of Placenta Tossetta, Giovanni n/a apoptosis oxidative stress base excision repair annexin A1 knockout mice high-risk pregnancy extracellular vesicles placental protein 13 (PP13) galectin 13 preeclampsia (PE) preterm delivery (PTD) size exclusion chromatography (SEC) corticosteroids newborn intrauterine hypoxia fetal hypoxia differentiation Hypoxia HIF-1 calcium platelets neonates early embryonic loss embryo-derived platelet-activating factor early pregnancy factor gestation pregnancy pre-implantation factor preeclampsia placenta fucosylated glycans antihypertensive therapy dopegyt cordaflex endothelial glycocalyx miscarriage pregnancy loss spontaneous abortion RPL genetic variant mutation implantation uterine receptivity cytokines recurrent implantation failure recurrent pregnancy loss miRNA NGS real-time PCR peripheral blood myometrium placenta accreta spectrum first-trimester screening trophoblast epigenetic FOXM1 blastocyst implantation trophoblast invasion and migration thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues Dear colleagues, The development and differentiation of placental villous trees are two key processes tightly regulated during pregnancy. In fact, several growth factors, their receptors and other types of molecules can regulate placental cell proliferation, differentiation, migration and invasion. Thus, an impairment of normal placental development can lead to a series of pregnancy pathologies, i.e., preeclampsia (PE), fetal growth restriction (FGR), gestational trophoblastic diseases (GTD) and gestational diabetes mellitus (GDM). Furthermore, external factors, such as microbial agents, chemicals and natural compounds, can affect placental development and function, impairing pregnancy outcomes. These pregnancy complications result in increased maternal and fetal mortality and morbidity, leading to life-long health implications in both mother and child. The aim of this Special Issue is to provide an overview of placental development and pathophysiology in order to better understand the molecular mechanisms involved in pregnancy. 2024-05-14T14:40:48Z 2024-05-14T14:40:48Z 2024 book ONIX_20240514_9783725807925_437 9783725807925 9783725807918 https://directory.doabooks.org/handle/20.500.12854/137841 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/9079 https://mdpi.com/books/pdfview/book/9079 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-0791-8 10.3390/books978-3-7258-0791-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725807925 9783725807918 224 open access |
| spellingShingle | n/a apoptosis oxidative stress base excision repair annexin A1 knockout mice high-risk pregnancy extracellular vesicles placental protein 13 (PP13) galectin 13 preeclampsia (PE) preterm delivery (PTD) size exclusion chromatography (SEC) corticosteroids newborn intrauterine hypoxia fetal hypoxia differentiation Hypoxia HIF-1 calcium platelets neonates early embryonic loss embryo-derived platelet-activating factor early pregnancy factor gestation pregnancy pre-implantation factor preeclampsia placenta fucosylated glycans antihypertensive therapy dopegyt cordaflex endothelial glycocalyx miscarriage pregnancy loss spontaneous abortion RPL genetic variant mutation implantation uterine receptivity cytokines recurrent implantation failure recurrent pregnancy loss miRNA NGS real-time PCR peripheral blood myometrium placenta accreta spectrum first-trimester screening trophoblast epigenetic FOXM1 blastocyst implantation trophoblast invasion and migration thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues Physiology and Pathophysiology of Placenta |
| title | Physiology and Pathophysiology of Placenta |
| title_full | Physiology and Pathophysiology of Placenta |
| title_fullStr | Physiology and Pathophysiology of Placenta |
| title_full_unstemmed | Physiology and Pathophysiology of Placenta |
| title_short | Physiology and Pathophysiology of Placenta |
| title_sort | physiology and pathophysiology of placenta |
| topic | n/a apoptosis oxidative stress base excision repair annexin A1 knockout mice high-risk pregnancy extracellular vesicles placental protein 13 (PP13) galectin 13 preeclampsia (PE) preterm delivery (PTD) size exclusion chromatography (SEC) corticosteroids newborn intrauterine hypoxia fetal hypoxia differentiation Hypoxia HIF-1 calcium platelets neonates early embryonic loss embryo-derived platelet-activating factor early pregnancy factor gestation pregnancy pre-implantation factor preeclampsia placenta fucosylated glycans antihypertensive therapy dopegyt cordaflex endothelial glycocalyx miscarriage pregnancy loss spontaneous abortion RPL genetic variant mutation implantation uterine receptivity cytokines recurrent implantation failure recurrent pregnancy loss miRNA NGS real-time PCR peripheral blood myometrium placenta accreta spectrum first-trimester screening trophoblast epigenetic FOXM1 blastocyst implantation trophoblast invasion and migration thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues |
| topic_facet | n/a apoptosis oxidative stress base excision repair annexin A1 knockout mice high-risk pregnancy extracellular vesicles placental protein 13 (PP13) galectin 13 preeclampsia (PE) preterm delivery (PTD) size exclusion chromatography (SEC) corticosteroids newborn intrauterine hypoxia fetal hypoxia differentiation Hypoxia HIF-1 calcium platelets neonates early embryonic loss embryo-derived platelet-activating factor early pregnancy factor gestation pregnancy pre-implantation factor preeclampsia placenta fucosylated glycans antihypertensive therapy dopegyt cordaflex endothelial glycocalyx miscarriage pregnancy loss spontaneous abortion RPL genetic variant mutation implantation uterine receptivity cytokines recurrent implantation failure recurrent pregnancy loss miRNA NGS real-time PCR peripheral blood myometrium placenta accreta spectrum first-trimester screening trophoblast epigenetic FOXM1 blastocyst implantation trophoblast invasion and migration thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues |
| url | ONIX_20240514_9783725807925_437 |