Genetic, Epigenetic, Environmental, and Pharmacological Models for Neuroscience, Neurologic Diseases, and Psychiatric Disorders: Advancement in Bench-to-Bedside Translational Research

The Special Issue, "Genetic, Epigenetic, Environmental, and Pharmacological Models for Neuroscience, Neurologic Diseases, and Psychiatric Disorders: Advancement in Bench-to-Bedside Translational Research," delves into the complexities of neurological and psychiatric disorders, which affect millions...

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collection Directory of Open Access Books
description The Special Issue, "Genetic, Epigenetic, Environmental, and Pharmacological Models for Neuroscience, Neurologic Diseases, and Psychiatric Disorders: Advancement in Bench-to-Bedside Translational Research," delves into the complexities of neurological and psychiatric disorders, which affect millions worldwide. Despite advances, the etiology and pathogenesis of these disorders remain largely unknown, and current treatments often fall short or have adverse effects. This issue emphasizes the urgent need for new strategies to prevent, diagnose, and treat these disorders. It underscores the importance of establishing reliable models that can recapitulate the complex interactions between genetic, epigenetic, environmental, and pharmacological factors contributing to these disorders. The issue presents 12 articles covering a wide range of topics and methods in neuroscience and neurology, highlighting the potential of novel interventions that can modulate the molecular and functional alterations underlying these disorders. It aims to stimulate further research and collaboration among researchers and clinicians, inspire new ideas and innovations, and ultimately benefit patients and society. Readers can explore the diverse and exciting topics presented in this collection. We extend our gratitude to all authors and reviewers for their contributions to this Special Issue.
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publisher MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-1378762024-05-14T14:48:17Z Genetic, Epigenetic, Environmental, and Pharmacological Models for Neuroscience, Neurologic Diseases, and Psychiatric Disorders: Advancement in Bench-to-Bedside Translational Research Tanaka, Masaru epilepsy surgery medically refractory focal epilepsy presurgical evaluation MRI-negative patients discordant electroclinical and MRI data metabolic PET hybrid [18F]-FDG PET/MRI preoperative workflow concordance analysis epilepsy team aspirin resistance genetic markers genetics machine learning CatBoost ischemic stroke SNP pharmacogenetics platelet aggregation biochip primary headache migraine trigeminal system CGRP nNOS neurogenic inflammation animal model inflammatory soup dura mater estrogen behavior respiratory sinus arrhythmia directed information flow neural pacemaker-like activity fMRI-related anxiety anxiety management causal coupling breathing rhythm neural BOLD oscillations cardio-respiratory coupling breathing-entrained oscillations transient receptor potential channels antibody reperfusion injury middle cerebral artery occlusion model vascular protection hypoxia stroke therapy age groups attention brain cognition default mode network executive function exercise magnetic resonance imaging memory mental health depression cardiovascular disease obesity diabetes civilization diseases mental disorders risk factors inflammation interleukins comorbidity cord blood stem cell transplantation genetic vectors vascular endothelial growth factor A transcriptome secretome biosafety genetic therapy oxidative stresses neuroinflammation traumatic brain injuries intensive care sedatives antioxidant effects biologic monitoring barbiturates electron spin resonance translational research Parkinson’s disease transcranial direct current stimulation motor skill cerebellum cerebellar stimulation motor learning manual dexterity dopamine basal ganglia transfer of motor learning translational neuroscience neuroplasticity aphasia rehabilitation language impairment cognitive recovery animals language physical health psychosis risk CHR-P n/a thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues The Special Issue, "Genetic, Epigenetic, Environmental, and Pharmacological Models for Neuroscience, Neurologic Diseases, and Psychiatric Disorders: Advancement in Bench-to-Bedside Translational Research," delves into the complexities of neurological and psychiatric disorders, which affect millions worldwide. Despite advances, the etiology and pathogenesis of these disorders remain largely unknown, and current treatments often fall short or have adverse effects. This issue emphasizes the urgent need for new strategies to prevent, diagnose, and treat these disorders. It underscores the importance of establishing reliable models that can recapitulate the complex interactions between genetic, epigenetic, environmental, and pharmacological factors contributing to these disorders. The issue presents 12 articles covering a wide range of topics and methods in neuroscience and neurology, highlighting the potential of novel interventions that can modulate the molecular and functional alterations underlying these disorders. It aims to stimulate further research and collaboration among researchers and clinicians, inspire new ideas and innovations, and ultimately benefit patients and society. Readers can explore the diverse and exciting topics presented in this collection. We extend our gratitude to all authors and reviewers for their contributions to this Special Issue. 2024-05-14T14:48:12Z 2024-05-14T14:48:12Z 2024 book ONIX_20240514_9783725808212_472 9783725808212 9783725808229 https://directory.doabooks.org/handle/20.500.12854/137876 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/9117 https://mdpi.com/books/pdfview/book/9117 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-0822-9 10.3390/books978-3-7258-0822-9 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725808212 9783725808229 248 open access
spellingShingle epilepsy surgery
medically refractory focal epilepsy
presurgical evaluation
MRI-negative patients
discordant electroclinical and MRI data
metabolic PET
hybrid [18F]-FDG PET/MRI
preoperative workflow
concordance analysis
epilepsy team
aspirin resistance
genetic markers
genetics
machine learning
CatBoost
ischemic stroke
SNP
pharmacogenetics
platelet aggregation
biochip
primary headache
migraine
trigeminal system
CGRP
nNOS
neurogenic inflammation
animal model
inflammatory soup
dura mater
estrogen
behavior
respiratory sinus arrhythmia
directed information flow
neural pacemaker-like activity
fMRI-related anxiety
anxiety management
causal coupling
breathing rhythm
neural BOLD oscillations
cardio-respiratory coupling
breathing-entrained oscillations
transient receptor potential channels
antibody
reperfusion injury
middle cerebral artery occlusion
model
vascular
protection
hypoxia
stroke
therapy
age groups
attention
brain
cognition
default mode network
executive function
exercise
magnetic resonance imaging
memory
mental health
depression
cardiovascular disease
obesity
diabetes
civilization diseases
mental disorders
risk factors
inflammation
interleukins
comorbidity
cord blood stem cell transplantation
genetic vectors
vascular endothelial growth factor A
transcriptome
secretome
biosafety
genetic therapy
oxidative stresses
neuroinflammation
traumatic brain injuries
intensive care
sedatives
antioxidant effects
biologic monitoring
barbiturates
electron spin resonance
translational research
Parkinson’s disease
transcranial direct current stimulation
motor skill
cerebellum
cerebellar stimulation
motor learning
manual dexterity
dopamine
basal ganglia
transfer of motor learning
translational neuroscience
neuroplasticity
aphasia
rehabilitation
language impairment
cognitive recovery
animals
language
physical health
psychosis
risk
CHR-P
n/a
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues
Genetic, Epigenetic, Environmental, and Pharmacological Models for Neuroscience, Neurologic Diseases, and Psychiatric Disorders: Advancement in Bench-to-Bedside Translational Research
title Genetic, Epigenetic, Environmental, and Pharmacological Models for Neuroscience, Neurologic Diseases, and Psychiatric Disorders: Advancement in Bench-to-Bedside Translational Research
title_full Genetic, Epigenetic, Environmental, and Pharmacological Models for Neuroscience, Neurologic Diseases, and Psychiatric Disorders: Advancement in Bench-to-Bedside Translational Research
title_fullStr Genetic, Epigenetic, Environmental, and Pharmacological Models for Neuroscience, Neurologic Diseases, and Psychiatric Disorders: Advancement in Bench-to-Bedside Translational Research
title_full_unstemmed Genetic, Epigenetic, Environmental, and Pharmacological Models for Neuroscience, Neurologic Diseases, and Psychiatric Disorders: Advancement in Bench-to-Bedside Translational Research
title_short Genetic, Epigenetic, Environmental, and Pharmacological Models for Neuroscience, Neurologic Diseases, and Psychiatric Disorders: Advancement in Bench-to-Bedside Translational Research
title_sort genetic epigenetic environmental and pharmacological models for neuroscience neurologic diseases and psychiatric disorders advancement in bench to bedside translational research
topic epilepsy surgery
medically refractory focal epilepsy
presurgical evaluation
MRI-negative patients
discordant electroclinical and MRI data
metabolic PET
hybrid [18F]-FDG PET/MRI
preoperative workflow
concordance analysis
epilepsy team
aspirin resistance
genetic markers
genetics
machine learning
CatBoost
ischemic stroke
SNP
pharmacogenetics
platelet aggregation
biochip
primary headache
migraine
trigeminal system
CGRP
nNOS
neurogenic inflammation
animal model
inflammatory soup
dura mater
estrogen
behavior
respiratory sinus arrhythmia
directed information flow
neural pacemaker-like activity
fMRI-related anxiety
anxiety management
causal coupling
breathing rhythm
neural BOLD oscillations
cardio-respiratory coupling
breathing-entrained oscillations
transient receptor potential channels
antibody
reperfusion injury
middle cerebral artery occlusion
model
vascular
protection
hypoxia
stroke
therapy
age groups
attention
brain
cognition
default mode network
executive function
exercise
magnetic resonance imaging
memory
mental health
depression
cardiovascular disease
obesity
diabetes
civilization diseases
mental disorders
risk factors
inflammation
interleukins
comorbidity
cord blood stem cell transplantation
genetic vectors
vascular endothelial growth factor A
transcriptome
secretome
biosafety
genetic therapy
oxidative stresses
neuroinflammation
traumatic brain injuries
intensive care
sedatives
antioxidant effects
biologic monitoring
barbiturates
electron spin resonance
translational research
Parkinson’s disease
transcranial direct current stimulation
motor skill
cerebellum
cerebellar stimulation
motor learning
manual dexterity
dopamine
basal ganglia
transfer of motor learning
translational neuroscience
neuroplasticity
aphasia
rehabilitation
language impairment
cognitive recovery
animals
language
physical health
psychosis
risk
CHR-P
n/a
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues
topic_facet epilepsy surgery
medically refractory focal epilepsy
presurgical evaluation
MRI-negative patients
discordant electroclinical and MRI data
metabolic PET
hybrid [18F]-FDG PET/MRI
preoperative workflow
concordance analysis
epilepsy team
aspirin resistance
genetic markers
genetics
machine learning
CatBoost
ischemic stroke
SNP
pharmacogenetics
platelet aggregation
biochip
primary headache
migraine
trigeminal system
CGRP
nNOS
neurogenic inflammation
animal model
inflammatory soup
dura mater
estrogen
behavior
respiratory sinus arrhythmia
directed information flow
neural pacemaker-like activity
fMRI-related anxiety
anxiety management
causal coupling
breathing rhythm
neural BOLD oscillations
cardio-respiratory coupling
breathing-entrained oscillations
transient receptor potential channels
antibody
reperfusion injury
middle cerebral artery occlusion
model
vascular
protection
hypoxia
stroke
therapy
age groups
attention
brain
cognition
default mode network
executive function
exercise
magnetic resonance imaging
memory
mental health
depression
cardiovascular disease
obesity
diabetes
civilization diseases
mental disorders
risk factors
inflammation
interleukins
comorbidity
cord blood stem cell transplantation
genetic vectors
vascular endothelial growth factor A
transcriptome
secretome
biosafety
genetic therapy
oxidative stresses
neuroinflammation
traumatic brain injuries
intensive care
sedatives
antioxidant effects
biologic monitoring
barbiturates
electron spin resonance
translational research
Parkinson’s disease
transcranial direct current stimulation
motor skill
cerebellum
cerebellar stimulation
motor learning
manual dexterity
dopamine
basal ganglia
transfer of motor learning
translational neuroscience
neuroplasticity
aphasia
rehabilitation
language impairment
cognitive recovery
animals
language
physical health
psychosis
risk
CHR-P
n/a
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues
url ONIX_20240514_9783725808212_472