Seminal Vesicles in Autosomal Dominant Polycystic Kidney Disease
Extra-renal manifestations of autosomal dominant polycystic kidney disease (ADPKD) have been known to involve male reproductive organs, including cysts in testis, epididymis, seminal vesicles, and prostate. The reported prevalence of seminal vesicle cysts in patients with ADPKD varies widely, from 6...
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| Формат: | Online |
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| Язык: | английский |
| Опубликовано: |
Exon Publications
2024
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| Online-ссылка: | https://directory.doabooks.org/handle/20.500.12854/138174 |
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| _version_ | 1869516884788903936 |
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| collection | Directory of Open Access Books |
| description | Extra-renal manifestations of autosomal dominant polycystic kidney disease (ADPKD) have been known to involve male reproductive organs, including cysts in testis, epididymis, seminal vesicles, and prostate. The reported prevalence of seminal vesicle cysts in patients with ADPKD varies widely, from 6% by computed tomography (CT) to 21%–60% by transrectal ultrasonography. However, seminal vesicles in ADPKD that are dilated, with a diameter greater than 10 mm by magnetic resonance imaging (MRI), are “megavesicles”. This is a separate entity from seminal vesicle cysts and has a prevalence of 23% in ADPKD patients, but is not known to occur in patients without ADPKD. The basis of these cystic changes and megavesicles has not been established, but may be explained by an imbalance between cell growth/proliferation inhibitors and stimulators analogous to mechanisms in renal tubular epithelial cells, hepatic ducts, and in the vasculature. Male infertility has been associated with ADPKD, although a causal role of seminal tract abnormalities has not been established. In this chapter, the anatomic abnormalities of seminal vesicles in ADPKD and their clinical significance will be discussed. |
| format | Online |
| id | doab-20.500.12854ir-138174 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | Exon Publications |
| publisherStr | Exon Publications |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1381742024-05-21T23:48:53Z Seminal Vesicles in Autosomal Dominant Polycystic Kidney Disease autosomal dominant polycystic kidney disease megavesicles seminal vesicles seminal vesicle cysts MJR Extra-renal manifestations of autosomal dominant polycystic kidney disease (ADPKD) have been known to involve male reproductive organs, including cysts in testis, epididymis, seminal vesicles, and prostate. The reported prevalence of seminal vesicle cysts in patients with ADPKD varies widely, from 6% by computed tomography (CT) to 21%–60% by transrectal ultrasonography. However, seminal vesicles in ADPKD that are dilated, with a diameter greater than 10 mm by magnetic resonance imaging (MRI), are “megavesicles”. This is a separate entity from seminal vesicle cysts and has a prevalence of 23% in ADPKD patients, but is not known to occur in patients without ADPKD. The basis of these cystic changes and megavesicles has not been established, but may be explained by an imbalance between cell growth/proliferation inhibitors and stimulators analogous to mechanisms in renal tubular epithelial cells, hepatic ducts, and in the vasculature. Male infertility has been associated with ADPKD, although a causal role of seminal tract abnormalities has not been established. In this chapter, the anatomic abnormalities of seminal vesicles in ADPKD and their clinical significance will be discussed. Published 2024-05-21T23:48:49Z 2024-05-21T23:48:49Z 2015-11-18 chapter 978-0-9944381-0-2 https://directory.doabooks.org/handle/20.500.12854/138174 eng image/jpeg Attribution-NonCommercial-NoDerivatives 4.0 International https://exonpublications.com/index.php/exon/article/view/86 Exon Publications Polycystic Kidney Disease https://doi.org/10.15586/codon.pkd.2015.ch18 https://doi.org/10.15586/codon.pkd.2015.ch18 2d6001a3-9e06-4979-bf02-6974e313eb24 01173f6b-d01d-49c3-b18e-93cfe3a0383d 978-0-9944381-0-2 443-455 Brisbane(AU) open access |
| spellingShingle | autosomal dominant polycystic kidney disease megavesicles seminal vesicles seminal vesicle cysts MJR Seminal Vesicles in Autosomal Dominant Polycystic Kidney Disease |
| title | Seminal Vesicles in Autosomal Dominant Polycystic Kidney Disease |
| title_full | Seminal Vesicles in Autosomal Dominant Polycystic Kidney Disease |
| title_fullStr | Seminal Vesicles in Autosomal Dominant Polycystic Kidney Disease |
| title_full_unstemmed | Seminal Vesicles in Autosomal Dominant Polycystic Kidney Disease |
| title_short | Seminal Vesicles in Autosomal Dominant Polycystic Kidney Disease |
| title_sort | seminal vesicles in autosomal dominant polycystic kidney disease |
| topic | autosomal dominant polycystic kidney disease megavesicles seminal vesicles seminal vesicle cysts MJR |
| topic_facet | autosomal dominant polycystic kidney disease megavesicles seminal vesicles seminal vesicle cysts MJR |
| url | https://directory.doabooks.org/handle/20.500.12854/138174 |