Engineering and Characterisation of Novel Nanomedicine Formulations
Over the last few decades, nanomedicine has become a hot topic in formulation science regarding selectively delivering drugs to target tissues. Nanomedicines can modify drug release and encapsulate poorly soluble drugs, allowing for a selective targeting and minimizing adverse effects. This is of ke...
में बचाया:
| स्वरूप: | Online |
|---|---|
| भाषा: | अंग्रेज़ी |
| प्रकाशित: |
MDPI - Multidisciplinary Digital Publishing Institute
2024
|
| विषय: | |
| ऑनलाइन पहुंच: | ONIX_20240704_9783725810963_40 |
| टैग: |
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!
|
| _version_ | 1869521349819498496 |
|---|---|
| collection | Directory of Open Access Books |
| description | Over the last few decades, nanomedicine has become a hot topic in formulation science regarding selectively delivering drugs to target tissues. Nanomedicines can modify drug release and encapsulate poorly soluble drugs, allowing for a selective targeting and minimizing adverse effects. This is of key importance in antitumoral and anti-infectious therapies, in which undesired drug release can lead to severe damage to healthy tissues. Moreover, they protect drugs from degradation, allowing for the the delivery of RNA. This reprint encompasses works describing the design, development and characterization of lipid nanomedicines, dendrimers and virus nanoparticles among others, as well as the evaluation of their toxicity and their anticancer and antifungal efficacy. Moreover, it analyzes the quality assessment of nanomedicines under clinical investigation. |
| format | Online |
| id | doab-20.500.12854ir-139244 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1392442024-07-04T09:31:47Z Engineering and Characterisation of Novel Nanomedicine Formulations Fernández García, Raquel Bolás-Fernández, Francisco Fraguas-Sánchez, Ana Isabel solid lipid nanoparticles hydrogel antifungal terbinafin Candida albicans clinical trials investigational medicinal products nanocarrier nanomedicine quality regulatory rotavirus S60-VP8* pseudovirus nanoparticle rotavirus vaccine rotavirus VP8* non-replicating rotavirus vaccine norovirus S60 nanoparticle microfluidics liposomes manufacture engineering scale-up triple negative breast cancer cisplatin hypoxia nanoparticle diffusion solid tumors rate of drug release metastatic potential acute toxicity breast cancer metastasis exosomes doxorubicin perylenediimide biological properties cancer cytotoxicity metal complexes silver copper PAMAM dendrimer Ang-(1-7) cardiac ischemia/reperfusion Mas receptor surface chemistry dendrimer generation toxicity ethosome Zingiber zerumbet Linn skin permeation fungal infection biological identity biological fluids flow field flow fractionation (FFF)-multidetection hyperthermia treatment intravenous administration magnetic nanoparticles native characterization protein corona pH-sensitive liposomes coencapsulation simvastatin acute myeloid leukemia targeted delivery siRNA lipid nanoparticles (LNPs) very-late antigen-4 (VLA-4) bone marrow targeting functional cyclized polyethylene glycol PEGylation of laponite hybrid nanoparticles drug delivery n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQP Pharmacy / dispensing Over the last few decades, nanomedicine has become a hot topic in formulation science regarding selectively delivering drugs to target tissues. Nanomedicines can modify drug release and encapsulate poorly soluble drugs, allowing for a selective targeting and minimizing adverse effects. This is of key importance in antitumoral and anti-infectious therapies, in which undesired drug release can lead to severe damage to healthy tissues. Moreover, they protect drugs from degradation, allowing for the the delivery of RNA. This reprint encompasses works describing the design, development and characterization of lipid nanomedicines, dendrimers and virus nanoparticles among others, as well as the evaluation of their toxicity and their anticancer and antifungal efficacy. Moreover, it analyzes the quality assessment of nanomedicines under clinical investigation. 2024-07-04T09:31:43Z 2024-07-04T09:31:43Z 2024 book ONIX_20240704_9783725810963_40 9783725810963 9783725810956 https://directory.doabooks.org/handle/20.500.12854/139244 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/9239 https://mdpi.com/books/pdfview/book/9239 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-1095-6 10.3390/books978-3-7258-1095-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725810963 9783725810956 270 open access |
| spellingShingle | solid lipid nanoparticles hydrogel antifungal terbinafin Candida albicans clinical trials investigational medicinal products nanocarrier nanomedicine quality regulatory rotavirus S60-VP8* pseudovirus nanoparticle rotavirus vaccine rotavirus VP8* non-replicating rotavirus vaccine norovirus S60 nanoparticle microfluidics liposomes manufacture engineering scale-up triple negative breast cancer cisplatin hypoxia nanoparticle diffusion solid tumors rate of drug release metastatic potential acute toxicity breast cancer metastasis exosomes doxorubicin perylenediimide biological properties cancer cytotoxicity metal complexes silver copper PAMAM dendrimer Ang-(1-7) cardiac ischemia/reperfusion Mas receptor surface chemistry dendrimer generation toxicity ethosome Zingiber zerumbet Linn skin permeation fungal infection biological identity biological fluids flow field flow fractionation (FFF)-multidetection hyperthermia treatment intravenous administration magnetic nanoparticles native characterization protein corona pH-sensitive liposomes coencapsulation simvastatin acute myeloid leukemia targeted delivery siRNA lipid nanoparticles (LNPs) very-late antigen-4 (VLA-4) bone marrow targeting functional cyclized polyethylene glycol PEGylation of laponite hybrid nanoparticles drug delivery n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQP Pharmacy / dispensing Engineering and Characterisation of Novel Nanomedicine Formulations |
| title | Engineering and Characterisation of Novel Nanomedicine Formulations |
| title_full | Engineering and Characterisation of Novel Nanomedicine Formulations |
| title_fullStr | Engineering and Characterisation of Novel Nanomedicine Formulations |
| title_full_unstemmed | Engineering and Characterisation of Novel Nanomedicine Formulations |
| title_short | Engineering and Characterisation of Novel Nanomedicine Formulations |
| title_sort | engineering and characterisation of novel nanomedicine formulations |
| topic | solid lipid nanoparticles hydrogel antifungal terbinafin Candida albicans clinical trials investigational medicinal products nanocarrier nanomedicine quality regulatory rotavirus S60-VP8* pseudovirus nanoparticle rotavirus vaccine rotavirus VP8* non-replicating rotavirus vaccine norovirus S60 nanoparticle microfluidics liposomes manufacture engineering scale-up triple negative breast cancer cisplatin hypoxia nanoparticle diffusion solid tumors rate of drug release metastatic potential acute toxicity breast cancer metastasis exosomes doxorubicin perylenediimide biological properties cancer cytotoxicity metal complexes silver copper PAMAM dendrimer Ang-(1-7) cardiac ischemia/reperfusion Mas receptor surface chemistry dendrimer generation toxicity ethosome Zingiber zerumbet Linn skin permeation fungal infection biological identity biological fluids flow field flow fractionation (FFF)-multidetection hyperthermia treatment intravenous administration magnetic nanoparticles native characterization protein corona pH-sensitive liposomes coencapsulation simvastatin acute myeloid leukemia targeted delivery siRNA lipid nanoparticles (LNPs) very-late antigen-4 (VLA-4) bone marrow targeting functional cyclized polyethylene glycol PEGylation of laponite hybrid nanoparticles drug delivery n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQP Pharmacy / dispensing |
| topic_facet | solid lipid nanoparticles hydrogel antifungal terbinafin Candida albicans clinical trials investigational medicinal products nanocarrier nanomedicine quality regulatory rotavirus S60-VP8* pseudovirus nanoparticle rotavirus vaccine rotavirus VP8* non-replicating rotavirus vaccine norovirus S60 nanoparticle microfluidics liposomes manufacture engineering scale-up triple negative breast cancer cisplatin hypoxia nanoparticle diffusion solid tumors rate of drug release metastatic potential acute toxicity breast cancer metastasis exosomes doxorubicin perylenediimide biological properties cancer cytotoxicity metal complexes silver copper PAMAM dendrimer Ang-(1-7) cardiac ischemia/reperfusion Mas receptor surface chemistry dendrimer generation toxicity ethosome Zingiber zerumbet Linn skin permeation fungal infection biological identity biological fluids flow field flow fractionation (FFF)-multidetection hyperthermia treatment intravenous administration magnetic nanoparticles native characterization protein corona pH-sensitive liposomes coencapsulation simvastatin acute myeloid leukemia targeted delivery siRNA lipid nanoparticles (LNPs) very-late antigen-4 (VLA-4) bone marrow targeting functional cyclized polyethylene glycol PEGylation of laponite hybrid nanoparticles drug delivery n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQP Pharmacy / dispensing |
| url | ONIX_20240704_9783725810963_40 |