Systemic Autoinflammatory Diseases—Clinical Rheumatic Challenges Series 2
Autoinflammation, as a relatively new field in clinical rheumatology, has gained increasing importance in recent years. The number of identified entities and affected patients has gradually increased, and some of the involved pathways have already been identified. This progress allows for a deeper u...
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| Format: | Online |
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| Language: | English |
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MDPI - Multidisciplinary Digital Publishing Institute
2024
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| Online Access: | ONIX_20240704_9783725810499_67 |
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| description | Autoinflammation, as a relatively new field in clinical rheumatology, has gained increasing importance in recent years. The number of identified entities and affected patients has gradually increased, and some of the involved pathways have already been identified. This progress allows for a deeper understanding of the closely linked diseases, such as inflammasomopathies, interferonopathies, relopathies, and proteasome-associated syndromes. These insights have not only improved their classification, but have also helped us to identify new treatment targets of pro-inflammatory cytokines, including IL-1ß, IL-6, interferon-, and TNF-alpha. Nevertheless, there is still an urgent medical need, especially in the recognition of syndromes of undifferentiated recurrent fever and reliable outcome measures, for the confirmation of data from controlled clinical trials, in addition to data from registers regarding patients’ long-term experiences. This Special Issue welcomed all types of papers on the broad spectrum of clinical characteristics, prognosis, pathophysiology, and treatment of autoinflammatory diseases. The goal of this Special Issue is to further raise awareness of autoinflammatory processes and to better separate them from well-established autoimmune diseases. It is clear that we have entered a new age in this complex field, as rheumatology is increasing linked to immunology. |
| format | Online |
| id | doab-20.500.12854ir-139271 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1392712024-07-04T09:34:43Z Systemic Autoinflammatory Diseases—Clinical Rheumatic Challenges Series 2 Feist, Eugen autoimmunity inflammation fibrosis COVID-19 SARS-CoV-2 vaccination anti-IL-1 drugs anakinra canakinumab antibody response Morbus Adamantiades–Behçet intracardiac thrombus rheumatology autoinflammation IL-23 rheumatoid arthritis systemic lupus erythematosus ankylosing spondylitis psoriatic arthritis sclerostin Wnt/?-catenin pathway autoinflammatory diseases SARS-CoV-2 vaccination familial Mediterranean fever adult-onset Still’s disease cryopyrin-associated periodic syndrome systemic autoinflammatory diseases IL-17 autoimmune epigenetics biological drugs C-reactive protein (CRP) fever of unknown origin (FUO) functional hyperthermia (FH) psychiatric disorder psychogenic fever imaging myelodysplastic syndrome VEXAS syndrome familial Mediterranean fever (FMF) Behcet’s disease diagnosis misdiagnoses patient survey pain fatigue autoinflammatory disease FMF CAPS TRAPS remission personalized medicine effectiveness exposure–response outcome monitoring thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCM Immunology Autoinflammation, as a relatively new field in clinical rheumatology, has gained increasing importance in recent years. The number of identified entities and affected patients has gradually increased, and some of the involved pathways have already been identified. This progress allows for a deeper understanding of the closely linked diseases, such as inflammasomopathies, interferonopathies, relopathies, and proteasome-associated syndromes. These insights have not only improved their classification, but have also helped us to identify new treatment targets of pro-inflammatory cytokines, including IL-1ß, IL-6, interferon-, and TNF-alpha. Nevertheless, there is still an urgent medical need, especially in the recognition of syndromes of undifferentiated recurrent fever and reliable outcome measures, for the confirmation of data from controlled clinical trials, in addition to data from registers regarding patients’ long-term experiences. This Special Issue welcomed all types of papers on the broad spectrum of clinical characteristics, prognosis, pathophysiology, and treatment of autoinflammatory diseases. The goal of this Special Issue is to further raise awareness of autoinflammatory processes and to better separate them from well-established autoimmune diseases. It is clear that we have entered a new age in this complex field, as rheumatology is increasing linked to immunology. 2024-07-04T09:34:40Z 2024-07-04T09:34:40Z 2024 book ONIX_20240704_9783725810499_67 9783725810499 9783725810505 https://directory.doabooks.org/handle/20.500.12854/139271 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/9267 https://mdpi.com/books/pdfview/book/9267 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-1050-5 10.3390/books978-3-7258-1050-5 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725810499 9783725810505 154 open access |
| spellingShingle | autoimmunity inflammation fibrosis COVID-19 SARS-CoV-2 vaccination anti-IL-1 drugs anakinra canakinumab antibody response Morbus Adamantiades–Behçet intracardiac thrombus rheumatology autoinflammation IL-23 rheumatoid arthritis systemic lupus erythematosus ankylosing spondylitis psoriatic arthritis sclerostin Wnt/?-catenin pathway autoinflammatory diseases SARS-CoV-2 vaccination familial Mediterranean fever adult-onset Still’s disease cryopyrin-associated periodic syndrome systemic autoinflammatory diseases IL-17 autoimmune epigenetics biological drugs C-reactive protein (CRP) fever of unknown origin (FUO) functional hyperthermia (FH) psychiatric disorder psychogenic fever imaging myelodysplastic syndrome VEXAS syndrome familial Mediterranean fever (FMF) Behcet’s disease diagnosis misdiagnoses patient survey pain fatigue autoinflammatory disease FMF CAPS TRAPS remission personalized medicine effectiveness exposure–response outcome monitoring thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCM Immunology Systemic Autoinflammatory Diseases—Clinical Rheumatic Challenges Series 2 |
| title | Systemic Autoinflammatory Diseases—Clinical Rheumatic Challenges Series 2 |
| title_full | Systemic Autoinflammatory Diseases—Clinical Rheumatic Challenges Series 2 |
| title_fullStr | Systemic Autoinflammatory Diseases—Clinical Rheumatic Challenges Series 2 |
| title_full_unstemmed | Systemic Autoinflammatory Diseases—Clinical Rheumatic Challenges Series 2 |
| title_short | Systemic Autoinflammatory Diseases—Clinical Rheumatic Challenges Series 2 |
| title_sort | systemic autoinflammatory diseases clinical rheumatic challenges series 2 |
| topic | autoimmunity inflammation fibrosis COVID-19 SARS-CoV-2 vaccination anti-IL-1 drugs anakinra canakinumab antibody response Morbus Adamantiades–Behçet intracardiac thrombus rheumatology autoinflammation IL-23 rheumatoid arthritis systemic lupus erythematosus ankylosing spondylitis psoriatic arthritis sclerostin Wnt/?-catenin pathway autoinflammatory diseases SARS-CoV-2 vaccination familial Mediterranean fever adult-onset Still’s disease cryopyrin-associated periodic syndrome systemic autoinflammatory diseases IL-17 autoimmune epigenetics biological drugs C-reactive protein (CRP) fever of unknown origin (FUO) functional hyperthermia (FH) psychiatric disorder psychogenic fever imaging myelodysplastic syndrome VEXAS syndrome familial Mediterranean fever (FMF) Behcet’s disease diagnosis misdiagnoses patient survey pain fatigue autoinflammatory disease FMF CAPS TRAPS remission personalized medicine effectiveness exposure–response outcome monitoring thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCM Immunology |
| topic_facet | autoimmunity inflammation fibrosis COVID-19 SARS-CoV-2 vaccination anti-IL-1 drugs anakinra canakinumab antibody response Morbus Adamantiades–Behçet intracardiac thrombus rheumatology autoinflammation IL-23 rheumatoid arthritis systemic lupus erythematosus ankylosing spondylitis psoriatic arthritis sclerostin Wnt/?-catenin pathway autoinflammatory diseases SARS-CoV-2 vaccination familial Mediterranean fever adult-onset Still’s disease cryopyrin-associated periodic syndrome systemic autoinflammatory diseases IL-17 autoimmune epigenetics biological drugs C-reactive protein (CRP) fever of unknown origin (FUO) functional hyperthermia (FH) psychiatric disorder psychogenic fever imaging myelodysplastic syndrome VEXAS syndrome familial Mediterranean fever (FMF) Behcet’s disease diagnosis misdiagnoses patient survey pain fatigue autoinflammatory disease FMF CAPS TRAPS remission personalized medicine effectiveness exposure–response outcome monitoring thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCM Immunology |
| url | ONIX_20240704_9783725810499_67 |