The Mode of Actions of the Current Point-of-Care Treatments for Osteoarthritis of the Knee
Point-of-care treatments are now the focus of attention for osteoarthritis of the knee (OAK). Cellular therapies, which can be performed on an outpatient clinic basis, are rapidly expanding in free practice. Platelet-rich plasma (PRP) therapy for OAK is a prime example of such therapies. It is seen...
में बचाया:
| स्वरूप: | Online |
|---|---|
| भाषा: | अंग्रेज़ी |
| प्रकाशित: |
MDPI - Multidisciplinary Digital Publishing Institute
2024
|
| विषय: | |
| ऑनलाइन पहुंच: | ONIX_20240704_9783725811083_90 |
| टैग: |
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!
|
| _version_ | 1869518230078357504 |
|---|---|
| collection | Directory of Open Access Books |
| description | Point-of-care treatments are now the focus of attention for osteoarthritis of the knee (OAK). Cellular therapies, which can be performed on an outpatient clinic basis, are rapidly expanding in free practice. Platelet-rich plasma (PRP) therapy for OAK is a prime example of such therapies. It is seen as an unmet medical need that fills the gap between surgical and conservative therapy. In other words, even though it is not an innovative regenerative medicine and cannot improve the disease itself by modifying the tissue structure, point-of-care cell therapy appears to have become an established treatment, advanced by patients' desire for some improvement in symptoms without the need for surgery. This Special Issue covers the current use of point-of-care therapies and potential future candidates, from basic research to clinical practice. |
| format | Online |
| id | doab-20.500.12854ir-139294 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1392942024-07-04T09:38:16Z The Mode of Actions of the Current Point-of-Care Treatments for Osteoarthritis of the Knee Sato, Masato platelet rich plasma autologous protein solution macrophage osteoarthritis pain nerve growth factor (NGF) intra-articular injection diagnosis management surgery cell therapy embryonic stem cells induced pluripotent stem cells mesenchymal stem cells exosome point-of-care therapy osteoarthritis of the knee cartilage regeneration knee joint disease modifying drugs cartilage bone remodeling inflammation platelet-rich plasma ozone hyaluronic acid autologous anti-inflammatory concentrated bone marrow aspirate mechanism of action MSC synovial fluid mode of action injection synovium knee TSG-6 PRG-4 BMP-2 cell sheet minimally invasive treatment disease-modifying osteoarthritis drug gene therapy oligonucleotide therapeutics silent information regulator 2 ortholog 1 (SIRT1) knock-in mice anti-adhesive membrane knee adhesion E8002 arthrofibrosis myofibroblast thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Point-of-care treatments are now the focus of attention for osteoarthritis of the knee (OAK). Cellular therapies, which can be performed on an outpatient clinic basis, are rapidly expanding in free practice. Platelet-rich plasma (PRP) therapy for OAK is a prime example of such therapies. It is seen as an unmet medical need that fills the gap between surgical and conservative therapy. In other words, even though it is not an innovative regenerative medicine and cannot improve the disease itself by modifying the tissue structure, point-of-care cell therapy appears to have become an established treatment, advanced by patients' desire for some improvement in symptoms without the need for surgery. This Special Issue covers the current use of point-of-care therapies and potential future candidates, from basic research to clinical practice. 2024-07-04T09:38:05Z 2024-07-04T09:38:05Z 2024 book ONIX_20240704_9783725811083_90 9783725811083 9783725811076 https://directory.doabooks.org/handle/20.500.12854/139294 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/9290 https://mdpi.com/books/pdfview/book/9290 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-1107-6 10.3390/books978-3-7258-1107-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725811083 9783725811076 170 open access |
| spellingShingle | platelet rich plasma autologous protein solution macrophage osteoarthritis pain nerve growth factor (NGF) intra-articular injection diagnosis management surgery cell therapy embryonic stem cells induced pluripotent stem cells mesenchymal stem cells exosome point-of-care therapy osteoarthritis of the knee cartilage regeneration knee joint disease modifying drugs cartilage bone remodeling inflammation platelet-rich plasma ozone hyaluronic acid autologous anti-inflammatory concentrated bone marrow aspirate mechanism of action MSC synovial fluid mode of action injection synovium knee TSG-6 PRG-4 BMP-2 cell sheet minimally invasive treatment disease-modifying osteoarthritis drug gene therapy oligonucleotide therapeutics silent information regulator 2 ortholog 1 (SIRT1) knock-in mice anti-adhesive membrane knee adhesion E8002 arthrofibrosis myofibroblast thema EDItEUR::P Mathematics and Science::PS Biology, life sciences The Mode of Actions of the Current Point-of-Care Treatments for Osteoarthritis of the Knee |
| title | The Mode of Actions of the Current Point-of-Care Treatments for Osteoarthritis of the Knee |
| title_full | The Mode of Actions of the Current Point-of-Care Treatments for Osteoarthritis of the Knee |
| title_fullStr | The Mode of Actions of the Current Point-of-Care Treatments for Osteoarthritis of the Knee |
| title_full_unstemmed | The Mode of Actions of the Current Point-of-Care Treatments for Osteoarthritis of the Knee |
| title_short | The Mode of Actions of the Current Point-of-Care Treatments for Osteoarthritis of the Knee |
| title_sort | mode of actions of the current point of care treatments for osteoarthritis of the knee |
| topic | platelet rich plasma autologous protein solution macrophage osteoarthritis pain nerve growth factor (NGF) intra-articular injection diagnosis management surgery cell therapy embryonic stem cells induced pluripotent stem cells mesenchymal stem cells exosome point-of-care therapy osteoarthritis of the knee cartilage regeneration knee joint disease modifying drugs cartilage bone remodeling inflammation platelet-rich plasma ozone hyaluronic acid autologous anti-inflammatory concentrated bone marrow aspirate mechanism of action MSC synovial fluid mode of action injection synovium knee TSG-6 PRG-4 BMP-2 cell sheet minimally invasive treatment disease-modifying osteoarthritis drug gene therapy oligonucleotide therapeutics silent information regulator 2 ortholog 1 (SIRT1) knock-in mice anti-adhesive membrane knee adhesion E8002 arthrofibrosis myofibroblast thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | platelet rich plasma autologous protein solution macrophage osteoarthritis pain nerve growth factor (NGF) intra-articular injection diagnosis management surgery cell therapy embryonic stem cells induced pluripotent stem cells mesenchymal stem cells exosome point-of-care therapy osteoarthritis of the knee cartilage regeneration knee joint disease modifying drugs cartilage bone remodeling inflammation platelet-rich plasma ozone hyaluronic acid autologous anti-inflammatory concentrated bone marrow aspirate mechanism of action MSC synovial fluid mode of action injection synovium knee TSG-6 PRG-4 BMP-2 cell sheet minimally invasive treatment disease-modifying osteoarthritis drug gene therapy oligonucleotide therapeutics silent information regulator 2 ortholog 1 (SIRT1) knock-in mice anti-adhesive membrane knee adhesion E8002 arthrofibrosis myofibroblast thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20240704_9783725811083_90 |