Dietary Supplements in Cardiovascular and Metabolic Diseases
This Special Issue begins with two preclinical studies on bergamot fruit extract (Citrus bergamia) showing reductions in oxidative stress and dyslipidemia both in vitro and in vivo. Additionally, a review explores the potential therapeutic use of combining SGLT2 inhibitors with plant extracts. In an...
Збережено в:
| Формат: | Online |
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| Мова: | Англійська |
| Опубліковано: |
MDPI - Multidisciplinary Digital Publishing Institute
2024
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| Предмети: | |
| Онлайн доступ: | ONIX_20240704_9783725812950_169 |
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| _version_ | 1869522210209660928 |
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| collection | Directory of Open Access Books |
| description | This Special Issue begins with two preclinical studies on bergamot fruit extract (Citrus bergamia) showing reductions in oxidative stress and dyslipidemia both in vitro and in vivo. Additionally, a review explores the potential therapeutic use of combining SGLT2 inhibitors with plant extracts. In another in vivo study, humanized mice supplemented with L-carnitine and essential oil emulsions exhibited prebiotic effects on gut microbiota, reducing plasma trimethylamine N-oxide (TMAO) levels and increasing fecal short-chain fatty acids (SCFAs). Preclinical studies also examined the impact of copper nanoparticles on oxidative stress and vascular relaxation, and assessed the quality of herbal teas and dietary supplements, revealing deficiencies in their nutraceutical content. Two reviews highlight the health benefits of astaxanthin and taurine. Clinical studies include a retrospective analysis linking glucosamine usage to increased cardiovascular risk in osteoarthritis patients, and a trial demonstrating the efficacy of L-Arginine plus vitamin C supplementation in long-COVID patients. The issue concludes with three placebo-controlled trials: one showing Coenzyme Q10 plus NADH benefits on fatigue and quality of life in chronic fatigue syndrome patients, another revealing the antioxidant effects of water-soluble tomato concentrate in healthy adults, and a third highlighting the positive impact of bergamot polyphenolic fraction phytosome, artichoke extracts, Q10 phytosome, and zinc on lipid profiles, inflammation, NAFLD, and endothelial reactivity in hypercholesterolemic individuals. |
| format | Online |
| id | doab-20.500.12854ir-139373 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1393732024-07-04T09:47:34Z Dietary Supplements in Cardiovascular and Metabolic Diseases Trimarco, Bruno Santulli, Gaetano chronic fatigue syndrome coenzyme Q10 myalgic encephalomyelitis mitochondria nonrestorative sleep NADH quality of life aging 20-HETE furegrelate HET0016 indomethacin NS-398 SQ-29,548 thromboxane-A2 hypercholesterolemia red yeast rice (RYR) bergamot polyphenolic fraction (BPF) malondialdehyde (MDA) oxidative stress proprotein convertase subtilisin/kexin type 9 (PCSK9) astaxanthin cardiometabolic disease metabolic syndrome systematic review meta-analysis dietary supplement nutraceutical compound cholesterol artichoke bergamot water-soluble tomato concentrate platelet apoptosis crossover clinical trial glucosamine cardiovascular disease osteoarthritis epidemiology diabetes insulin resistance lipid accumulation inflammation reactive oxygen species (ROS) SGLT2 inhibitors nutraceutical supplementation cardiovascular risk carbonyl cytokine chemokine nutraceutical parsley pentosidine prebiotic protein carbonyl rosemary savory short-chain fatty acid trimethylamine N-oxide post-acute COVID-19 syndrome SARS-CoV-2 6 min walk test handgrip strength flow-mediated dilation nitric oxide nutraceuticals oral supplement persistent symptoms mulberry Morus alba 1-deoxynojirimycin DNJ dietary supplements PLS regression salt loading endothelial cell mitochondrial dysfunction polyphenols stroke SHRSP 2-aminoethanesulfonic acid energy drinks metabolism supplements tauric acid taurine n/a thema EDItEUR::P Mathematics and Science thema EDItEUR::P Mathematics and Science::PS Biology, life sciences This Special Issue begins with two preclinical studies on bergamot fruit extract (Citrus bergamia) showing reductions in oxidative stress and dyslipidemia both in vitro and in vivo. Additionally, a review explores the potential therapeutic use of combining SGLT2 inhibitors with plant extracts. In another in vivo study, humanized mice supplemented with L-carnitine and essential oil emulsions exhibited prebiotic effects on gut microbiota, reducing plasma trimethylamine N-oxide (TMAO) levels and increasing fecal short-chain fatty acids (SCFAs). Preclinical studies also examined the impact of copper nanoparticles on oxidative stress and vascular relaxation, and assessed the quality of herbal teas and dietary supplements, revealing deficiencies in their nutraceutical content. Two reviews highlight the health benefits of astaxanthin and taurine. Clinical studies include a retrospective analysis linking glucosamine usage to increased cardiovascular risk in osteoarthritis patients, and a trial demonstrating the efficacy of L-Arginine plus vitamin C supplementation in long-COVID patients. The issue concludes with three placebo-controlled trials: one showing Coenzyme Q10 plus NADH benefits on fatigue and quality of life in chronic fatigue syndrome patients, another revealing the antioxidant effects of water-soluble tomato concentrate in healthy adults, and a third highlighting the positive impact of bergamot polyphenolic fraction phytosome, artichoke extracts, Q10 phytosome, and zinc on lipid profiles, inflammation, NAFLD, and endothelial reactivity in hypercholesterolemic individuals. 2024-07-04T09:47:32Z 2024-07-04T09:47:32Z 2024 book ONIX_20240704_9783725812950_169 9783725812950 9783725812967 https://directory.doabooks.org/handle/20.500.12854/139373 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/9371 https://mdpi.com/books/pdfview/book/9371 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-1296-7 10.3390/books978-3-7258-1296-7 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725812950 9783725812967 200 open access |
| spellingShingle | chronic fatigue syndrome coenzyme Q10 myalgic encephalomyelitis mitochondria nonrestorative sleep NADH quality of life aging 20-HETE furegrelate HET0016 indomethacin NS-398 SQ-29,548 thromboxane-A2 hypercholesterolemia red yeast rice (RYR) bergamot polyphenolic fraction (BPF) malondialdehyde (MDA) oxidative stress proprotein convertase subtilisin/kexin type 9 (PCSK9) astaxanthin cardiometabolic disease metabolic syndrome systematic review meta-analysis dietary supplement nutraceutical compound cholesterol artichoke bergamot water-soluble tomato concentrate platelet apoptosis crossover clinical trial glucosamine cardiovascular disease osteoarthritis epidemiology diabetes insulin resistance lipid accumulation inflammation reactive oxygen species (ROS) SGLT2 inhibitors nutraceutical supplementation cardiovascular risk carbonyl cytokine chemokine nutraceutical parsley pentosidine prebiotic protein carbonyl rosemary savory short-chain fatty acid trimethylamine N-oxide post-acute COVID-19 syndrome SARS-CoV-2 6 min walk test handgrip strength flow-mediated dilation nitric oxide nutraceuticals oral supplement persistent symptoms mulberry Morus alba 1-deoxynojirimycin DNJ dietary supplements PLS regression salt loading endothelial cell mitochondrial dysfunction polyphenols stroke SHRSP 2-aminoethanesulfonic acid energy drinks metabolism supplements tauric acid taurine n/a thema EDItEUR::P Mathematics and Science thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Dietary Supplements in Cardiovascular and Metabolic Diseases |
| title | Dietary Supplements in Cardiovascular and Metabolic Diseases |
| title_full | Dietary Supplements in Cardiovascular and Metabolic Diseases |
| title_fullStr | Dietary Supplements in Cardiovascular and Metabolic Diseases |
| title_full_unstemmed | Dietary Supplements in Cardiovascular and Metabolic Diseases |
| title_short | Dietary Supplements in Cardiovascular and Metabolic Diseases |
| title_sort | dietary supplements in cardiovascular and metabolic diseases |
| topic | chronic fatigue syndrome coenzyme Q10 myalgic encephalomyelitis mitochondria nonrestorative sleep NADH quality of life aging 20-HETE furegrelate HET0016 indomethacin NS-398 SQ-29,548 thromboxane-A2 hypercholesterolemia red yeast rice (RYR) bergamot polyphenolic fraction (BPF) malondialdehyde (MDA) oxidative stress proprotein convertase subtilisin/kexin type 9 (PCSK9) astaxanthin cardiometabolic disease metabolic syndrome systematic review meta-analysis dietary supplement nutraceutical compound cholesterol artichoke bergamot water-soluble tomato concentrate platelet apoptosis crossover clinical trial glucosamine cardiovascular disease osteoarthritis epidemiology diabetes insulin resistance lipid accumulation inflammation reactive oxygen species (ROS) SGLT2 inhibitors nutraceutical supplementation cardiovascular risk carbonyl cytokine chemokine nutraceutical parsley pentosidine prebiotic protein carbonyl rosemary savory short-chain fatty acid trimethylamine N-oxide post-acute COVID-19 syndrome SARS-CoV-2 6 min walk test handgrip strength flow-mediated dilation nitric oxide nutraceuticals oral supplement persistent symptoms mulberry Morus alba 1-deoxynojirimycin DNJ dietary supplements PLS regression salt loading endothelial cell mitochondrial dysfunction polyphenols stroke SHRSP 2-aminoethanesulfonic acid energy drinks metabolism supplements tauric acid taurine n/a thema EDItEUR::P Mathematics and Science thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | chronic fatigue syndrome coenzyme Q10 myalgic encephalomyelitis mitochondria nonrestorative sleep NADH quality of life aging 20-HETE furegrelate HET0016 indomethacin NS-398 SQ-29,548 thromboxane-A2 hypercholesterolemia red yeast rice (RYR) bergamot polyphenolic fraction (BPF) malondialdehyde (MDA) oxidative stress proprotein convertase subtilisin/kexin type 9 (PCSK9) astaxanthin cardiometabolic disease metabolic syndrome systematic review meta-analysis dietary supplement nutraceutical compound cholesterol artichoke bergamot water-soluble tomato concentrate platelet apoptosis crossover clinical trial glucosamine cardiovascular disease osteoarthritis epidemiology diabetes insulin resistance lipid accumulation inflammation reactive oxygen species (ROS) SGLT2 inhibitors nutraceutical supplementation cardiovascular risk carbonyl cytokine chemokine nutraceutical parsley pentosidine prebiotic protein carbonyl rosemary savory short-chain fatty acid trimethylamine N-oxide post-acute COVID-19 syndrome SARS-CoV-2 6 min walk test handgrip strength flow-mediated dilation nitric oxide nutraceuticals oral supplement persistent symptoms mulberry Morus alba 1-deoxynojirimycin DNJ dietary supplements PLS regression salt loading endothelial cell mitochondrial dysfunction polyphenols stroke SHRSP 2-aminoethanesulfonic acid energy drinks metabolism supplements tauric acid taurine n/a thema EDItEUR::P Mathematics and Science thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20240704_9783725812950_169 |