Vascular, Oxidative and Inflammatory Dysregulation in Neurodegenerative Diseases: Current Status and Future Therapeutic Perspectives

Up to one billion individuals globally may be impacted by neurological illnesses, according to recent World Health Organization (WHO) research. Medical definitions of neurological illnesses include conditions that impact not only the brain but also the spinal cord and nerves in the human body. A var...

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collection Directory of Open Access Books
description Up to one billion individuals globally may be impacted by neurological illnesses, according to recent World Health Organization (WHO) research. Medical definitions of neurological illnesses include conditions that impact not only the brain but also the spinal cord and nerves in the human body. A variety of symptoms may be brought on by structural, biochemical, or electrical anomalies in the brain, spinal cord, or other nerves. Among the most prevalent are neurodegenerative diseases like Alzheimer's and other dementias, strokes, migraines, multiple sclerosis, Parkinson's disease, amyotrophic lateral sclerosis, polyneuropathies, neurological infections, brain tumours, and conditions resulting from nervous system trauma like head injuries.
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institution Directory of Open Access Books
language eng
publishDate 2024
publishDateRange 2024
publishDateSort 2024
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
record_format ojs
spelling doab-20.500.12854ir-1394332024-07-04T09:54:42Z Vascular, Oxidative and Inflammatory Dysregulation in Neurodegenerative Diseases: Current Status and Future Therapeutic Perspectives Marchesi, Nicoletta BACE1 TSPAN3 VEGF ISM2 ELAV secretase PKC RACK1 ischemic stroke penumbra minocycline HuR RNA-binding protein inflammation motor test diabetic retinopathy neuroinflammation ROS ER stress NLRP3 inflammasome galectins P2X7R motor neuron disease autonomic system mortality non-invasive ventilation PEG NIMV vascular cardio-vascular ELAV/HuD BDNF folic acid neurodegenerative diseases Alzheimer’s disease CD163 white-matter hyperintensities mild cognitive impairment transcriptome oxidative stress amyotrophic lateral sclerosis reactive oxygen species stroke reperfusion treatment miRNA NGS hsa-miR-9-3p hsa-miR-9-5p enrichment analysis GO KEGG aging blood–brain barrier perivascular macrophage lymphatic system multiple sclerosis neurodegeneration vascular impairment whole-body cryotherapy thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology::MKGW Psychopharmacology Up to one billion individuals globally may be impacted by neurological illnesses, according to recent World Health Organization (WHO) research. Medical definitions of neurological illnesses include conditions that impact not only the brain but also the spinal cord and nerves in the human body. A variety of symptoms may be brought on by structural, biochemical, or electrical anomalies in the brain, spinal cord, or other nerves. Among the most prevalent are neurodegenerative diseases like Alzheimer's and other dementias, strokes, migraines, multiple sclerosis, Parkinson's disease, amyotrophic lateral sclerosis, polyneuropathies, neurological infections, brain tumours, and conditions resulting from nervous system trauma like head injuries. 2024-07-04T09:54:38Z 2024-07-04T09:54:38Z 2024 book ONIX_20240704_9783725814343_229 9783725814343 9783725814336 https://directory.doabooks.org/handle/20.500.12854/139433 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/9435 https://mdpi.com/books/pdfview/book/9435 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-1433-6 10.3390/books978-3-7258-1433-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725814343 9783725814336 224 open access
spellingShingle BACE1
TSPAN3
VEGF
ISM2
ELAV
secretase
PKC
RACK1
ischemic stroke
penumbra
minocycline
HuR
RNA-binding protein
inflammation
motor test
diabetic retinopathy
neuroinflammation
ROS
ER stress
NLRP3 inflammasome
galectins
P2X7R
motor neuron disease
autonomic system
mortality
non-invasive ventilation
PEG
NIMV
vascular
cardio-vascular
ELAV/HuD
BDNF
folic acid
neurodegenerative diseases
Alzheimer’s disease
CD163
white-matter hyperintensities
mild cognitive impairment
transcriptome
oxidative stress
amyotrophic lateral sclerosis
reactive oxygen species
stroke
reperfusion treatment
miRNA
NGS
hsa-miR-9-3p
hsa-miR-9-5p
enrichment analysis
GO
KEGG
aging
blood–brain barrier
perivascular macrophage
lymphatic system
multiple sclerosis
neurodegeneration
vascular impairment
whole-body cryotherapy
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology::MKGW Psychopharmacology
Vascular, Oxidative and Inflammatory Dysregulation in Neurodegenerative Diseases: Current Status and Future Therapeutic Perspectives
title Vascular, Oxidative and Inflammatory Dysregulation in Neurodegenerative Diseases: Current Status and Future Therapeutic Perspectives
title_full Vascular, Oxidative and Inflammatory Dysregulation in Neurodegenerative Diseases: Current Status and Future Therapeutic Perspectives
title_fullStr Vascular, Oxidative and Inflammatory Dysregulation in Neurodegenerative Diseases: Current Status and Future Therapeutic Perspectives
title_full_unstemmed Vascular, Oxidative and Inflammatory Dysregulation in Neurodegenerative Diseases: Current Status and Future Therapeutic Perspectives
title_short Vascular, Oxidative and Inflammatory Dysregulation in Neurodegenerative Diseases: Current Status and Future Therapeutic Perspectives
title_sort vascular oxidative and inflammatory dysregulation in neurodegenerative diseases current status and future therapeutic perspectives
topic BACE1
TSPAN3
VEGF
ISM2
ELAV
secretase
PKC
RACK1
ischemic stroke
penumbra
minocycline
HuR
RNA-binding protein
inflammation
motor test
diabetic retinopathy
neuroinflammation
ROS
ER stress
NLRP3 inflammasome
galectins
P2X7R
motor neuron disease
autonomic system
mortality
non-invasive ventilation
PEG
NIMV
vascular
cardio-vascular
ELAV/HuD
BDNF
folic acid
neurodegenerative diseases
Alzheimer’s disease
CD163
white-matter hyperintensities
mild cognitive impairment
transcriptome
oxidative stress
amyotrophic lateral sclerosis
reactive oxygen species
stroke
reperfusion treatment
miRNA
NGS
hsa-miR-9-3p
hsa-miR-9-5p
enrichment analysis
GO
KEGG
aging
blood–brain barrier
perivascular macrophage
lymphatic system
multiple sclerosis
neurodegeneration
vascular impairment
whole-body cryotherapy
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology::MKGW Psychopharmacology
topic_facet BACE1
TSPAN3
VEGF
ISM2
ELAV
secretase
PKC
RACK1
ischemic stroke
penumbra
minocycline
HuR
RNA-binding protein
inflammation
motor test
diabetic retinopathy
neuroinflammation
ROS
ER stress
NLRP3 inflammasome
galectins
P2X7R
motor neuron disease
autonomic system
mortality
non-invasive ventilation
PEG
NIMV
vascular
cardio-vascular
ELAV/HuD
BDNF
folic acid
neurodegenerative diseases
Alzheimer’s disease
CD163
white-matter hyperintensities
mild cognitive impairment
transcriptome
oxidative stress
amyotrophic lateral sclerosis
reactive oxygen species
stroke
reperfusion treatment
miRNA
NGS
hsa-miR-9-3p
hsa-miR-9-5p
enrichment analysis
GO
KEGG
aging
blood–brain barrier
perivascular macrophage
lymphatic system
multiple sclerosis
neurodegeneration
vascular impairment
whole-body cryotherapy
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology::MKGW Psychopharmacology
url ONIX_20240704_9783725814343_229