Antimicrobial Activity of Different Plant Extracts, Plant-Derived Compounds and Synthetic Derivatives of Natural Compounds on Pathogenic Microorganisms
The growing resistance of microorganisms, especially among clinical strains, to popular antibiotics used in the treatment of infectious diseases is a huge global problem. The problem with MDR (multidrug-resistant) strains is associated with significant mortality caused by these pathogenic microorgan...
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| Formato: | Online |
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| Idioma: | inglês |
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MDPI - Multidisciplinary Digital Publishing Institute
2024
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| Acesso em linha: | ONIX_20240704_9783725814244_237 |
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| description | The growing resistance of microorganisms, especially among clinical strains, to popular antibiotics used in the treatment of infectious diseases is a huge global problem. The problem with MDR (multidrug-resistant) strains is associated with significant mortality caused by these pathogenic microorganisms, especially in hospital environments. The search for new compounds of natural origin is crucial in solving this problem. Extraction is a simple method to isolate various compounds from raw plant material. Furthermore, different plant extracts have high biological activity, comparable to that of known drugs. However, in search of novel plant-derived compounds characterized with stronger biological activity than plant extracts, chemical modifications of natural compounds are helpful. Additionally, articles that present alternative methods of obtaining natural compounds with antimicrobial activity, e.g., as a result of biotransformation using whole cells of microorganisms or pure enzymes, are also welcome. It will be interesting to compare the antimicrobial activity of natural compounds and their synthetic derivatives but also different plant extracts with pure compounds, which are dominant in plants. Plant extracts and compounds obtained by chemical modifications or biotransformations may be the future of effective treatment of infectious diseases. |
| format | Online |
| id | doab-20.500.12854ir-139441 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
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| spelling | doab-20.500.12854ir-1394412024-07-04T09:55:39Z Antimicrobial Activity of Different Plant Extracts, Plant-Derived Compounds and Synthetic Derivatives of Natural Compounds on Pathogenic Microorganisms Koz?owska, Joanna Duda-Madej, Anna Campylobacter jejuni biofilm adhesion intercellular signaling lavandin formulations Rhodiola rosea proanthocyanidins flavonoids LuxS biofumigant sinigrin head blight Brassica juncea Eruca sativa Raphanus sativus naringenin naringenin derivatives antimicrobial activity anti-inflammatory activity antioxidant activity antifungal activity natural compounds essential oil antifungal agent Aspergillus flavus aflatoxin mechanism of action ADME biological activity GC-MS network analyses terpene volatiles Monteverdia ilicifolia Maytenus ilicifolia antioxidant capacity condensed tannins glycosylated flavonoids bioinformatics plant-derived compounds stingless bee honey pathogenic strains thyme essential oil antibacterial agent antibiofilm activity natural food preservatives foodborne illness pathogens Vernonia polyanthes glaucolide A UHPLC/Q-TOF-MS antibacterial activity methicillin-resistant Staphylococcus aureus carvacrol antimicrobial biotransformation Bioflux microfluidic conditions intestinal microflora thema EDItEUR::P Mathematics and Science::PS Biology, life sciences The growing resistance of microorganisms, especially among clinical strains, to popular antibiotics used in the treatment of infectious diseases is a huge global problem. The problem with MDR (multidrug-resistant) strains is associated with significant mortality caused by these pathogenic microorganisms, especially in hospital environments. The search for new compounds of natural origin is crucial in solving this problem. Extraction is a simple method to isolate various compounds from raw plant material. Furthermore, different plant extracts have high biological activity, comparable to that of known drugs. However, in search of novel plant-derived compounds characterized with stronger biological activity than plant extracts, chemical modifications of natural compounds are helpful. Additionally, articles that present alternative methods of obtaining natural compounds with antimicrobial activity, e.g., as a result of biotransformation using whole cells of microorganisms or pure enzymes, are also welcome. It will be interesting to compare the antimicrobial activity of natural compounds and their synthetic derivatives but also different plant extracts with pure compounds, which are dominant in plants. Plant extracts and compounds obtained by chemical modifications or biotransformations may be the future of effective treatment of infectious diseases. 2024-07-04T09:55:31Z 2024-07-04T09:55:31Z 2024 book ONIX_20240704_9783725814244_237 9783725814244 9783725814237 https://directory.doabooks.org/handle/20.500.12854/139441 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/9443 https://mdpi.com/books/pdfview/book/9443 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-1423-7 10.3390/books978-3-7258-1423-7 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725814244 9783725814237 218 open access |
| spellingShingle | Campylobacter jejuni biofilm adhesion intercellular signaling lavandin formulations Rhodiola rosea proanthocyanidins flavonoids LuxS biofumigant sinigrin head blight Brassica juncea Eruca sativa Raphanus sativus naringenin naringenin derivatives antimicrobial activity anti-inflammatory activity antioxidant activity antifungal activity natural compounds essential oil antifungal agent Aspergillus flavus aflatoxin mechanism of action ADME biological activity GC-MS network analyses terpene volatiles Monteverdia ilicifolia Maytenus ilicifolia antioxidant capacity condensed tannins glycosylated flavonoids bioinformatics plant-derived compounds stingless bee honey pathogenic strains thyme essential oil antibacterial agent antibiofilm activity natural food preservatives foodborne illness pathogens Vernonia polyanthes glaucolide A UHPLC/Q-TOF-MS antibacterial activity methicillin-resistant Staphylococcus aureus carvacrol antimicrobial biotransformation Bioflux microfluidic conditions intestinal microflora thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Antimicrobial Activity of Different Plant Extracts, Plant-Derived Compounds and Synthetic Derivatives of Natural Compounds on Pathogenic Microorganisms |
| title | Antimicrobial Activity of Different Plant Extracts, Plant-Derived Compounds and Synthetic Derivatives of Natural Compounds on Pathogenic Microorganisms |
| title_full | Antimicrobial Activity of Different Plant Extracts, Plant-Derived Compounds and Synthetic Derivatives of Natural Compounds on Pathogenic Microorganisms |
| title_fullStr | Antimicrobial Activity of Different Plant Extracts, Plant-Derived Compounds and Synthetic Derivatives of Natural Compounds on Pathogenic Microorganisms |
| title_full_unstemmed | Antimicrobial Activity of Different Plant Extracts, Plant-Derived Compounds and Synthetic Derivatives of Natural Compounds on Pathogenic Microorganisms |
| title_short | Antimicrobial Activity of Different Plant Extracts, Plant-Derived Compounds and Synthetic Derivatives of Natural Compounds on Pathogenic Microorganisms |
| title_sort | antimicrobial activity of different plant extracts plant derived compounds and synthetic derivatives of natural compounds on pathogenic microorganisms |
| topic | Campylobacter jejuni biofilm adhesion intercellular signaling lavandin formulations Rhodiola rosea proanthocyanidins flavonoids LuxS biofumigant sinigrin head blight Brassica juncea Eruca sativa Raphanus sativus naringenin naringenin derivatives antimicrobial activity anti-inflammatory activity antioxidant activity antifungal activity natural compounds essential oil antifungal agent Aspergillus flavus aflatoxin mechanism of action ADME biological activity GC-MS network analyses terpene volatiles Monteverdia ilicifolia Maytenus ilicifolia antioxidant capacity condensed tannins glycosylated flavonoids bioinformatics plant-derived compounds stingless bee honey pathogenic strains thyme essential oil antibacterial agent antibiofilm activity natural food preservatives foodborne illness pathogens Vernonia polyanthes glaucolide A UHPLC/Q-TOF-MS antibacterial activity methicillin-resistant Staphylococcus aureus carvacrol antimicrobial biotransformation Bioflux microfluidic conditions intestinal microflora thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | Campylobacter jejuni biofilm adhesion intercellular signaling lavandin formulations Rhodiola rosea proanthocyanidins flavonoids LuxS biofumigant sinigrin head blight Brassica juncea Eruca sativa Raphanus sativus naringenin naringenin derivatives antimicrobial activity anti-inflammatory activity antioxidant activity antifungal activity natural compounds essential oil antifungal agent Aspergillus flavus aflatoxin mechanism of action ADME biological activity GC-MS network analyses terpene volatiles Monteverdia ilicifolia Maytenus ilicifolia antioxidant capacity condensed tannins glycosylated flavonoids bioinformatics plant-derived compounds stingless bee honey pathogenic strains thyme essential oil antibacterial agent antibiofilm activity natural food preservatives foodborne illness pathogens Vernonia polyanthes glaucolide A UHPLC/Q-TOF-MS antibacterial activity methicillin-resistant Staphylococcus aureus carvacrol antimicrobial biotransformation Bioflux microfluidic conditions intestinal microflora thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20240704_9783725814244_237 |