Thirty Years since the Discovery of Toll-Like Receptors

Toll-like receptors (TLRs) have attracted interest due to their role in detecting pathogens and regulating the pro-inflammatory immune response. To date, 10 functional TLRs (TLR1–10) have been detected in humans. These TLRs control diverse immunological and embryonic development processes to maintai...

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Taal:Engels
Gepubliceerd in: IntechOpen 2024
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collection Directory of Open Access Books
description Toll-like receptors (TLRs) have attracted interest due to their role in detecting pathogens and regulating the pro-inflammatory immune response. To date, 10 functional TLRs (TLR1–10) have been detected in humans. These TLRs control diverse immunological and embryonic development processes to maintain immune homeostasis and healthy fetal growth and development. They recognize diverse pathogen-associated molecular patterns (PAMPs) and death/damage-associated molecular patterns (DAMPs) to maintain immune homeostasis via regulating diverse immunological processes. This book discusses TLRs from their evolution to immunological functions governing infection and inflammation pathogenesis, cancer immunology, and their interactions with other pro-inflammatory molecules generated during inflammation pathogenesis. It is a must-read for researchers interested in TLR biology and the role of TLRs in infection, immunity, and cancer.
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spelling doab-20.500.12854ir-1402102024-07-11T07:42:49Z Thirty Years since the Discovery of Toll-Like Receptors Kumar, Vijay Immunology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCM Immunology Toll-like receptors (TLRs) have attracted interest due to their role in detecting pathogens and regulating the pro-inflammatory immune response. To date, 10 functional TLRs (TLR1–10) have been detected in humans. These TLRs control diverse immunological and embryonic development processes to maintain immune homeostasis and healthy fetal growth and development. They recognize diverse pathogen-associated molecular patterns (PAMPs) and death/damage-associated molecular patterns (DAMPs) to maintain immune homeostasis via regulating diverse immunological processes. This book discusses TLRs from their evolution to immunological functions governing infection and inflammation pathogenesis, cancer immunology, and their interactions with other pro-inflammatory molecules generated during inflammation pathogenesis. It is a must-read for researchers interested in TLR biology and the role of TLRs in infection, immunity, and cancer. 2024-07-11T07:42:46Z 2024-07-11T07:42:46Z 2024 book ONIX_20240711_9781837694662_24 9781837694662 9781837694679 9781837694686 https://directory.doabooks.org/handle/20.500.12854/140210 eng image/jpeg n/a https://www.intechopen.com/books/1002150 https://intech-files.s3.amazonaws.com/a043Y00000vBvocQAC/0014054_Authors_Book%20%282024-03-28%2009%3A18%3A58%29.pdf IntechOpen IntechOpen 10.5772/intechopen.104331 10.5772/intechopen.104331 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781837694662 9781837694679 9781837694686 IntechOpen 106 open access
spellingShingle Immunology
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCM Immunology
Thirty Years since the Discovery of Toll-Like Receptors
title Thirty Years since the Discovery of Toll-Like Receptors
title_full Thirty Years since the Discovery of Toll-Like Receptors
title_fullStr Thirty Years since the Discovery of Toll-Like Receptors
title_full_unstemmed Thirty Years since the Discovery of Toll-Like Receptors
title_short Thirty Years since the Discovery of Toll-Like Receptors
title_sort thirty years since the discovery of toll like receptors
topic Immunology
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCM Immunology
topic_facet Immunology
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCM Immunology
url ONIX_20240711_9781837694662_24