Advances in Cancer Multimodal Approach: Biomarkers, Mechanisms, Surgical Procedures and Oncological Therapies
Cancer is the leading cause of death worldwide, accounting for more than 10 million deaths each year and an even larger number of patients who are diagnosed with this disease and have to undergo various procedures. All of this has happened following the increased number of risk factors that have imp...
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| פורמט: | Online |
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| שפה: | אנגלית |
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MDPI - Multidisciplinary Digital Publishing Institute
2024
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| נושאים: | |
| גישה מקוונת: | ONIX_20240906_9783725818433_50 |
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| _version_ | 1869517139991330816 |
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| collection | Directory of Open Access Books |
| description | Cancer is the leading cause of death worldwide, accounting for more than 10 million deaths each year and an even larger number of patients who are diagnosed with this disease and have to undergo various procedures. All of this has happened following the increased number of risk factors that have impacted our lives over the past few decades, such as tobacco use, obesity and different unhealthy diets, alcohol consumption, viral infections, and exposure to certain chemicals or radiation. Our goal as medical practitioners or scientists is to obtain the best outcome for our patients, from prophylactic procedures to a correct diagnosis, specific multimodal treatment, and rigorous follow-up. All of these factors have significantly improved in the last few years because of a better understanding of the genetic and molecular mechanisms of cancer development, the emergence of new technologies in cancer detection or surgical techniques, and breakthroughs in oncological therapies. However, there remains a huge field to explore, considering the current unknowns and the alert dynamics under which cancer evolves. Oncology is the medical field that requires the mobilization of most medical specialties in order to outline the particular profile of each individual patient and optimize the necessary treatment. |
| format | Online |
| id | doab-20.500.12854ir-143688 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1436882024-09-06T08:05:24Z Advances in Cancer Multimodal Approach: Biomarkers, Mechanisms, Surgical Procedures and Oncological Therapies Grigorean, Valentin Titus Cristian, Daniel Alin interstitial cells of Cajal cancer gastrointestinal tumors c-kit n/a comprehensive nursing service outcome prognostic factors prognostic score ovarian carcinoma adenocarcinoma gastric cancer MKN-45 cisplatin magnolol parathyroid carcinoma secondary hyperparathyroidism hypercalcemia brain metastases lung hepatoid adenocarcinoma K-RAS liquid biopsy ddPCR pediatric cancer two-dimensional gel electrophoresis MS-based proteomics metabolomics pharmacokinetics of anticancer drugs epigenetics chromatin modifications acute lymphoblastic leukemia Philadelphia chromosome relapse allogeneic stem cell transplantation colorectal obstruction cervical cancer HPV nerve-sparing radical hysterectomy radiochemotherapy checkpoint inhibitors CD34 regenerative stem cell cancer stem cells adjuvant chemotherapy neoadjuvant radiotherapy neoadjuvant radiochemotherapy rectal cancer tumor downstage Romanian oncologists hepatocellular carcinoma radiofrequency ablation salvage hepatectomy laparoscopic liver resection rhabdomyosarcoma spindle cell inguinal hernia adult radiotherapy DNA neoadjuvant therapy prognosis pain neoplasm non-invasive brain stimulation repetitive transcranial magnetic stimulation (rTMS) transcranial direct current stimulation (tDCS) cranial electric stimulation (CES) hemoglobin to red cell distribution width Hb/RDW ratio risk assessment DNA damage response germline mutation localized prostate cancer next-generation sequencing radiomics head and neck cancer lymph node breast cancer biomarkers serological histological translational medicine total neoadjuvant therapy chemoradiotherapy tumor stage PCR p16INK4a immunohistochemistry NSCLC Jordan breast cancers neoadjuvant chemotherapy breast cancer subtype biomarker p53 prognostic factor downstaging neoadjuvant treatment adenopathy thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Cancer is the leading cause of death worldwide, accounting for more than 10 million deaths each year and an even larger number of patients who are diagnosed with this disease and have to undergo various procedures. All of this has happened following the increased number of risk factors that have impacted our lives over the past few decades, such as tobacco use, obesity and different unhealthy diets, alcohol consumption, viral infections, and exposure to certain chemicals or radiation. Our goal as medical practitioners or scientists is to obtain the best outcome for our patients, from prophylactic procedures to a correct diagnosis, specific multimodal treatment, and rigorous follow-up. All of these factors have significantly improved in the last few years because of a better understanding of the genetic and molecular mechanisms of cancer development, the emergence of new technologies in cancer detection or surgical techniques, and breakthroughs in oncological therapies. However, there remains a huge field to explore, considering the current unknowns and the alert dynamics under which cancer evolves. Oncology is the medical field that requires the mobilization of most medical specialties in order to outline the particular profile of each individual patient and optimize the necessary treatment. 2024-09-06T08:05:16Z 2024-09-06T08:05:16Z 2024 book ONIX_20240906_9783725818433_50 9783725818433 9783725818440 https://directory.doabooks.org/handle/20.500.12854/143688 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/9705 https://mdpi.com/books/pdfview/book/9705 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-1844-0 10.3390/books978-3-7258-1844-0 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725818433 9783725818440 342 open access |
| spellingShingle | interstitial cells of Cajal cancer gastrointestinal tumors c-kit n/a comprehensive nursing service outcome prognostic factors prognostic score ovarian carcinoma adenocarcinoma gastric cancer MKN-45 cisplatin magnolol parathyroid carcinoma secondary hyperparathyroidism hypercalcemia brain metastases lung hepatoid adenocarcinoma K-RAS liquid biopsy ddPCR pediatric cancer two-dimensional gel electrophoresis MS-based proteomics metabolomics pharmacokinetics of anticancer drugs epigenetics chromatin modifications acute lymphoblastic leukemia Philadelphia chromosome relapse allogeneic stem cell transplantation colorectal obstruction cervical cancer HPV nerve-sparing radical hysterectomy radiochemotherapy checkpoint inhibitors CD34 regenerative stem cell cancer stem cells adjuvant chemotherapy neoadjuvant radiotherapy neoadjuvant radiochemotherapy rectal cancer tumor downstage Romanian oncologists hepatocellular carcinoma radiofrequency ablation salvage hepatectomy laparoscopic liver resection rhabdomyosarcoma spindle cell inguinal hernia adult radiotherapy DNA neoadjuvant therapy prognosis pain neoplasm non-invasive brain stimulation repetitive transcranial magnetic stimulation (rTMS) transcranial direct current stimulation (tDCS) cranial electric stimulation (CES) hemoglobin to red cell distribution width Hb/RDW ratio risk assessment DNA damage response germline mutation localized prostate cancer next-generation sequencing radiomics head and neck cancer lymph node breast cancer biomarkers serological histological translational medicine total neoadjuvant therapy chemoradiotherapy tumor stage PCR p16INK4a immunohistochemistry NSCLC Jordan breast cancers neoadjuvant chemotherapy breast cancer subtype biomarker p53 prognostic factor downstaging neoadjuvant treatment adenopathy thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Advances in Cancer Multimodal Approach: Biomarkers, Mechanisms, Surgical Procedures and Oncological Therapies |
| title | Advances in Cancer Multimodal Approach: Biomarkers, Mechanisms, Surgical Procedures and Oncological Therapies |
| title_full | Advances in Cancer Multimodal Approach: Biomarkers, Mechanisms, Surgical Procedures and Oncological Therapies |
| title_fullStr | Advances in Cancer Multimodal Approach: Biomarkers, Mechanisms, Surgical Procedures and Oncological Therapies |
| title_full_unstemmed | Advances in Cancer Multimodal Approach: Biomarkers, Mechanisms, Surgical Procedures and Oncological Therapies |
| title_short | Advances in Cancer Multimodal Approach: Biomarkers, Mechanisms, Surgical Procedures and Oncological Therapies |
| title_sort | advances in cancer multimodal approach biomarkers mechanisms surgical procedures and oncological therapies |
| topic | interstitial cells of Cajal cancer gastrointestinal tumors c-kit n/a comprehensive nursing service outcome prognostic factors prognostic score ovarian carcinoma adenocarcinoma gastric cancer MKN-45 cisplatin magnolol parathyroid carcinoma secondary hyperparathyroidism hypercalcemia brain metastases lung hepatoid adenocarcinoma K-RAS liquid biopsy ddPCR pediatric cancer two-dimensional gel electrophoresis MS-based proteomics metabolomics pharmacokinetics of anticancer drugs epigenetics chromatin modifications acute lymphoblastic leukemia Philadelphia chromosome relapse allogeneic stem cell transplantation colorectal obstruction cervical cancer HPV nerve-sparing radical hysterectomy radiochemotherapy checkpoint inhibitors CD34 regenerative stem cell cancer stem cells adjuvant chemotherapy neoadjuvant radiotherapy neoadjuvant radiochemotherapy rectal cancer tumor downstage Romanian oncologists hepatocellular carcinoma radiofrequency ablation salvage hepatectomy laparoscopic liver resection rhabdomyosarcoma spindle cell inguinal hernia adult radiotherapy DNA neoadjuvant therapy prognosis pain neoplasm non-invasive brain stimulation repetitive transcranial magnetic stimulation (rTMS) transcranial direct current stimulation (tDCS) cranial electric stimulation (CES) hemoglobin to red cell distribution width Hb/RDW ratio risk assessment DNA damage response germline mutation localized prostate cancer next-generation sequencing radiomics head and neck cancer lymph node breast cancer biomarkers serological histological translational medicine total neoadjuvant therapy chemoradiotherapy tumor stage PCR p16INK4a immunohistochemistry NSCLC Jordan breast cancers neoadjuvant chemotherapy breast cancer subtype biomarker p53 prognostic factor downstaging neoadjuvant treatment adenopathy thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| topic_facet | interstitial cells of Cajal cancer gastrointestinal tumors c-kit n/a comprehensive nursing service outcome prognostic factors prognostic score ovarian carcinoma adenocarcinoma gastric cancer MKN-45 cisplatin magnolol parathyroid carcinoma secondary hyperparathyroidism hypercalcemia brain metastases lung hepatoid adenocarcinoma K-RAS liquid biopsy ddPCR pediatric cancer two-dimensional gel electrophoresis MS-based proteomics metabolomics pharmacokinetics of anticancer drugs epigenetics chromatin modifications acute lymphoblastic leukemia Philadelphia chromosome relapse allogeneic stem cell transplantation colorectal obstruction cervical cancer HPV nerve-sparing radical hysterectomy radiochemotherapy checkpoint inhibitors CD34 regenerative stem cell cancer stem cells adjuvant chemotherapy neoadjuvant radiotherapy neoadjuvant radiochemotherapy rectal cancer tumor downstage Romanian oncologists hepatocellular carcinoma radiofrequency ablation salvage hepatectomy laparoscopic liver resection rhabdomyosarcoma spindle cell inguinal hernia adult radiotherapy DNA neoadjuvant therapy prognosis pain neoplasm non-invasive brain stimulation repetitive transcranial magnetic stimulation (rTMS) transcranial direct current stimulation (tDCS) cranial electric stimulation (CES) hemoglobin to red cell distribution width Hb/RDW ratio risk assessment DNA damage response germline mutation localized prostate cancer next-generation sequencing radiomics head and neck cancer lymph node breast cancer biomarkers serological histological translational medicine total neoadjuvant therapy chemoradiotherapy tumor stage PCR p16INK4a immunohistochemistry NSCLC Jordan breast cancers neoadjuvant chemotherapy breast cancer subtype biomarker p53 prognostic factor downstaging neoadjuvant treatment adenopathy thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| url | ONIX_20240906_9783725818433_50 |