Ion Channels and Neurological Disease
This Special Issue reprint aims to provide an update on the state of the art and new achievements in the research on altered structure/function relationship in the ion channels involved in neurological diseases’ pathophysiology. Of particular interest are drug screening and targeting, proposing nove...
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| Formato: | Online |
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| Idioma: | inglês |
| Publicado em: |
MDPI - Multidisciplinary Digital Publishing Institute
2024
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| Assuntos: | |
| Acesso em linha: | ONIX_20240906_9783725819294_60 |
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| _version_ | 1869516768598294528 |
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| collection | Directory of Open Access Books |
| description | This Special Issue reprint aims to provide an update on the state of the art and new achievements in the research on altered structure/function relationship in the ion channels involved in neurological diseases’ pathophysiology. Of particular interest are drug screening and targeting, proposing novel therapeutic avenues which can be developed to treat or alleviate mostly incurable diseases. Multi- and inter-disciplinary research contributions, often combining structural, functional, and/or pharmacological approaches with different methods/techniques, are presented. |
| format | Online |
| id | doab-20.500.12854ir-143698 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1436982024-09-06T08:06:57Z Ion Channels and Neurological Disease Musio, Carlo ryanodine receptor autophagy calcium signaling calcineurin Alzheimer’s disease Nav channel blockers epilepsy FHM3 intellectual disability neurodegeneration Parkinson’s disease amyotrophic lateral sclerosis CLC proteins endosome lysosome chloride transport developmental cerebellar ataxia Purkinje neuron intrinsic membrane excitability ion channels therapy voltage-gated sodium channels excitability hippocampus plasticity pharmacology GABAB receptors spinal cord dorsolateral funiculus afferents motoneurons nucleoporins membrane excitability neuronal activity neurodegenerative disease patch-clamp astrocytes glia glioblastoma transporter disease brain oscillations excitation inhibition induced pluripotent stem cells AMPA glutamate n/a thema EDItEUR::P Mathematics and Science thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PH Physics::PHV Applied physics::PHVN Biophysics This Special Issue reprint aims to provide an update on the state of the art and new achievements in the research on altered structure/function relationship in the ion channels involved in neurological diseases’ pathophysiology. Of particular interest are drug screening and targeting, proposing novel therapeutic avenues which can be developed to treat or alleviate mostly incurable diseases. Multi- and inter-disciplinary research contributions, often combining structural, functional, and/or pharmacological approaches with different methods/techniques, are presented. 2024-09-06T08:06:52Z 2024-09-06T08:06:52Z 2024 book ONIX_20240906_9783725819294_60 9783725819294 9783725819300 https://directory.doabooks.org/handle/20.500.12854/143698 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/9718 https://mdpi.com/books/pdfview/book/9718 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-1930-0 10.3390/books978-3-7258-1930-0 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725819294 9783725819300 208 open access |
| spellingShingle | ryanodine receptor autophagy calcium signaling calcineurin Alzheimer’s disease Nav channel blockers epilepsy FHM3 intellectual disability neurodegeneration Parkinson’s disease amyotrophic lateral sclerosis CLC proteins endosome lysosome chloride transport developmental cerebellar ataxia Purkinje neuron intrinsic membrane excitability ion channels therapy voltage-gated sodium channels excitability hippocampus plasticity pharmacology GABAB receptors spinal cord dorsolateral funiculus afferents motoneurons nucleoporins membrane excitability neuronal activity neurodegenerative disease patch-clamp astrocytes glia glioblastoma transporter disease brain oscillations excitation inhibition induced pluripotent stem cells AMPA glutamate n/a thema EDItEUR::P Mathematics and Science thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PH Physics::PHV Applied physics::PHVN Biophysics Ion Channels and Neurological Disease |
| title | Ion Channels and Neurological Disease |
| title_full | Ion Channels and Neurological Disease |
| title_fullStr | Ion Channels and Neurological Disease |
| title_full_unstemmed | Ion Channels and Neurological Disease |
| title_short | Ion Channels and Neurological Disease |
| title_sort | ion channels and neurological disease |
| topic | ryanodine receptor autophagy calcium signaling calcineurin Alzheimer’s disease Nav channel blockers epilepsy FHM3 intellectual disability neurodegeneration Parkinson’s disease amyotrophic lateral sclerosis CLC proteins endosome lysosome chloride transport developmental cerebellar ataxia Purkinje neuron intrinsic membrane excitability ion channels therapy voltage-gated sodium channels excitability hippocampus plasticity pharmacology GABAB receptors spinal cord dorsolateral funiculus afferents motoneurons nucleoporins membrane excitability neuronal activity neurodegenerative disease patch-clamp astrocytes glia glioblastoma transporter disease brain oscillations excitation inhibition induced pluripotent stem cells AMPA glutamate n/a thema EDItEUR::P Mathematics and Science thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PH Physics::PHV Applied physics::PHVN Biophysics |
| topic_facet | ryanodine receptor autophagy calcium signaling calcineurin Alzheimer’s disease Nav channel blockers epilepsy FHM3 intellectual disability neurodegeneration Parkinson’s disease amyotrophic lateral sclerosis CLC proteins endosome lysosome chloride transport developmental cerebellar ataxia Purkinje neuron intrinsic membrane excitability ion channels therapy voltage-gated sodium channels excitability hippocampus plasticity pharmacology GABAB receptors spinal cord dorsolateral funiculus afferents motoneurons nucleoporins membrane excitability neuronal activity neurodegenerative disease patch-clamp astrocytes glia glioblastoma transporter disease brain oscillations excitation inhibition induced pluripotent stem cells AMPA glutamate n/a thema EDItEUR::P Mathematics and Science thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PH Physics::PHV Applied physics::PHVN Biophysics |
| url | ONIX_20240906_9783725819294_60 |