Commemorative Issue Celebrating the 20th Anniversary of the Alzheimer’s Foundation of America: Understanding and Treating Alzheimer’s Disease
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects the lives of millions of people and their families around the globe. It results in a relentless decline in cognitive function, loss of judgment, change in personality, and neuropsychiatric and behavioral symptoms. Path...
Kaydedildi:
| Materyal Türü: | Online |
|---|---|
| Dil: | İngilizce |
| Baskı/Yayın Bilgisi: |
MDPI - Multidisciplinary Digital Publishing Institute
2024
|
| Konular: | |
| Online Erişim: | ONIX_20240906_9783725819676_75 |
| Etiketler: |
Etiket eklenmemiş, İlk siz ekleyin!
|
| _version_ | 1869514505738780672 |
|---|---|
| collection | Directory of Open Access Books |
| description | Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects the lives of millions of people and their families around the globe. It results in a relentless decline in cognitive function, loss of judgment, change in personality, and neuropsychiatric and behavioral symptoms. Pathologic features characteristic of AD are deposition in the brain of two types of misfolded proteins: β-amyloid in the form of extracellular plaques and tau protein in the form of intracellular neurofibrillary tangles. The causal mechanisms of AD are likely multi-factorial but are not yet completely understood. While we are making inroads, especially in the development of more accurate biomarkers for diagnosis, there is no curative treatment. The following compilation delves into the clinical and pathophysiologic aspects of AD while also addressing standard and cutting-edge treatments. Lifestyle and diet as modifiable risk factors are discussed while social and caregiver impact are given much-needed attention. The expert authors bring their unique insights and perspectives to one of the major health challenges of our time. This work serves as a repository for our current state of knowledge in the field of AD and as a resource for both health professionals and the general public. |
| format | Online |
| id | doab-20.500.12854ir-143713 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1437132024-09-06T08:09:12Z Commemorative Issue Celebrating the 20th Anniversary of the Alzheimer’s Foundation of America: Understanding and Treating Alzheimer’s Disease Reiss, Allison B. Pinkhasov, Aaron Alzheimer’s disease primary care physicians dementia knowledge and attitude early diagnosis and management barriers to diagnosis biomarkers plasma phospho-tau amyloid blood neurofilament light positron emission tomography magnetic resonance imaging plant-based diet B vitamins antioxidants vitamin K fiber cognition big data neurophysiology imaging Alzheimer’s disease (AD) telemedicine COVID-19 World Health Organization (WHO) depression anxiety caregiver burden traditional ideologies inflammation drug therapy diet lifestyle feature selection diagnostic algorithm Electrovestibulography cerebrovascular pathology gamma-aminobutyric acid frailty behavioral and psychological symptoms neuropsychiatric symptoms race dementia grief family caregiver depressive symptoms caregiver strain social support n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects the lives of millions of people and their families around the globe. It results in a relentless decline in cognitive function, loss of judgment, change in personality, and neuropsychiatric and behavioral symptoms. Pathologic features characteristic of AD are deposition in the brain of two types of misfolded proteins: β-amyloid in the form of extracellular plaques and tau protein in the form of intracellular neurofibrillary tangles. The causal mechanisms of AD are likely multi-factorial but are not yet completely understood. While we are making inroads, especially in the development of more accurate biomarkers for diagnosis, there is no curative treatment. The following compilation delves into the clinical and pathophysiologic aspects of AD while also addressing standard and cutting-edge treatments. Lifestyle and diet as modifiable risk factors are discussed while social and caregiver impact are given much-needed attention. The expert authors bring their unique insights and perspectives to one of the major health challenges of our time. This work serves as a repository for our current state of knowledge in the field of AD and as a resource for both health professionals and the general public. 2024-09-06T08:09:07Z 2024-09-06T08:09:07Z 2024 book ONIX_20240906_9783725819676_75 9783725819676 9783725819683 https://directory.doabooks.org/handle/20.500.12854/143713 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/9743 https://mdpi.com/books/pdfview/book/9743 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-1968-3 10.3390/books978-3-7258-1968-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725819676 9783725819683 198 open access |
| spellingShingle | Alzheimer’s disease primary care physicians dementia knowledge and attitude early diagnosis and management barriers to diagnosis biomarkers plasma phospho-tau amyloid blood neurofilament light positron emission tomography magnetic resonance imaging plant-based diet B vitamins antioxidants vitamin K fiber cognition big data neurophysiology imaging Alzheimer’s disease (AD) telemedicine COVID-19 World Health Organization (WHO) depression anxiety caregiver burden traditional ideologies inflammation drug therapy diet lifestyle feature selection diagnostic algorithm Electrovestibulography cerebrovascular pathology gamma-aminobutyric acid frailty behavioral and psychological symptoms neuropsychiatric symptoms race dementia grief family caregiver depressive symptoms caregiver strain social support n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology Commemorative Issue Celebrating the 20th Anniversary of the Alzheimer’s Foundation of America: Understanding and Treating Alzheimer’s Disease |
| title | Commemorative Issue Celebrating the 20th Anniversary of the Alzheimer’s Foundation of America: Understanding and Treating Alzheimer’s Disease |
| title_full | Commemorative Issue Celebrating the 20th Anniversary of the Alzheimer’s Foundation of America: Understanding and Treating Alzheimer’s Disease |
| title_fullStr | Commemorative Issue Celebrating the 20th Anniversary of the Alzheimer’s Foundation of America: Understanding and Treating Alzheimer’s Disease |
| title_full_unstemmed | Commemorative Issue Celebrating the 20th Anniversary of the Alzheimer’s Foundation of America: Understanding and Treating Alzheimer’s Disease |
| title_short | Commemorative Issue Celebrating the 20th Anniversary of the Alzheimer’s Foundation of America: Understanding and Treating Alzheimer’s Disease |
| title_sort | commemorative issue celebrating the 20th anniversary of the alzheimer s foundation of america understanding and treating alzheimer s disease |
| topic | Alzheimer’s disease primary care physicians dementia knowledge and attitude early diagnosis and management barriers to diagnosis biomarkers plasma phospho-tau amyloid blood neurofilament light positron emission tomography magnetic resonance imaging plant-based diet B vitamins antioxidants vitamin K fiber cognition big data neurophysiology imaging Alzheimer’s disease (AD) telemedicine COVID-19 World Health Organization (WHO) depression anxiety caregiver burden traditional ideologies inflammation drug therapy diet lifestyle feature selection diagnostic algorithm Electrovestibulography cerebrovascular pathology gamma-aminobutyric acid frailty behavioral and psychological symptoms neuropsychiatric symptoms race dementia grief family caregiver depressive symptoms caregiver strain social support n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology |
| topic_facet | Alzheimer’s disease primary care physicians dementia knowledge and attitude early diagnosis and management barriers to diagnosis biomarkers plasma phospho-tau amyloid blood neurofilament light positron emission tomography magnetic resonance imaging plant-based diet B vitamins antioxidants vitamin K fiber cognition big data neurophysiology imaging Alzheimer’s disease (AD) telemedicine COVID-19 World Health Organization (WHO) depression anxiety caregiver burden traditional ideologies inflammation drug therapy diet lifestyle feature selection diagnostic algorithm Electrovestibulography cerebrovascular pathology gamma-aminobutyric acid frailty behavioral and psychological symptoms neuropsychiatric symptoms race dementia grief family caregiver depressive symptoms caregiver strain social support n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology |
| url | ONIX_20240906_9783725819676_75 |