Therapeutic Drug Monitoring and Pharmacokinetics-Based Individualization of Drug Therapy

This compilation is a reprint of the Special Issue “Therapeutic drug monitoring and pharmacokinetics-based individualization of drug therapy” of the peer-reviewed journal Pharmaceutics (ISSN: 1999-4923). The primary aim of this Special Issue was to provide a platform for presenting the findings of r...

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Bibliografiske detaljer
Format:	Online
Sprog:	engelsk
Udgivet:	MDPI - Multidisciplinary Digital Publishing Institute 2024
Fag:	ganciclovir lung transplant recipients cystic fibrosis therapeutic drug monitoring covariates haloperidol pharmacokinetics delirium critical ill ICU dapagliflozin linagliptin fixed-dose combination products bioequivalence busulfan sulfolane myelofibrosis population pharmacokinetics heart transplantation acute rejection tacrolimus endomyocardial biopsies pharmacokinetic interactions heart transplant precision medicine clinical practice gentamicin population pharmacokinetic modeling external evaluation model re-estimation dosing nomogram long-acting antiretroviral therapy cabotegravir rilpivirine pharmacokinetic simulation TDM plasma level PK/PD dose–effect relationship LC–MS/MS CFTR modulators caftor ivacaftor lumacaftor tezacaftor elexacaftor population pharmacokinetic rivaroxaban atrial fibrillation direct oral anticoagulants Thai patient tobramycin model-informed precision dosing dalbavancin long-acting Gram-positive osteoarticular infections laparoscopic sleeve gastrectomy omeprazole modeling and simulation obesity treatment efficacy medication adherence schizophrenia spectrum and other psychotic disorders bipolar and related disorders depressive disorder cefiderocol antibiotics drug monitoring isavuconazole pediatric pharmacodynamics Bayesian fungal infection outcomes oral anticancer drugs oncology imatinib precision pharmacotherapy cerebrospinal fluid methotrexate children acute lymphoid leukemia external validation non-infectious uveitis (NIU) therapeutic drug monitoring (TDM) pharmacogenetics biological therapy limited sampling strategies population pharmacokinetic modelling semi-parametric simulation robustness area under the curve AUC glomerular filtration rate GFR tuberculosis rifampicin dried blood spots limited-sampling strategy pharmacokinetic boosting pharmacokinetic enhancement ritonavir cobicistat kinase inhibitors small molecule kinase inhibitors critical illness sepsis kidney injury biomarkers pediatric pharmacology Bayesian estimation piperacillin tazobactam nonparametric adaptive grid Bayesian models intensive care n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology
Online adgang:	ONIX_20240906_9783725820214_99
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Summary:	This compilation is a reprint of the Special Issue “Therapeutic drug monitoring and pharmacokinetics-based individualization of drug therapy” of the peer-reviewed journal Pharmaceutics (ISSN: 1999-4923). The primary aim of this Special Issue was to provide a platform for presenting the findings of research performed using novel computer software-based approaches for the pharmacokinetic interpretation of the results of therapeutic drug monitoring. The compilation involves nineteen research articles and five review papers published between 2022 and 2024. The areas covered include pharmacotherapy following organ transplant, the treatment of the severely or even critically ill using antiinfectives, precision oncology, mental illness, cystic fibrosis, anticoagulant therapy, the treatment of diabetes, and ophthalmology.

Therapeutic Drug Monitoring and Pharmacokinetics-Based Individualization of Drug Therapy

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