Current Practices in Sickle Cell Disease
Sickle cell anemia is an inherited disorder of the globin chains that causes hemolysis and chronic organ damage. Sickle cell anemia is the most common form of sickle cell disease (SCD), with a lifelong affliction of hemolytic anemia requiring blood transfusions, pain crises, and organ damage. Since...
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| Sprog: | engelsk |
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IntechOpen
2024
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| Online adgang: | ONIX_20241025_9780854669196_81 |
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| description | Sickle cell anemia is an inherited disorder of the globin chains that causes hemolysis and chronic organ damage. Sickle cell anemia is the most common form of sickle cell disease (SCD), with a lifelong affliction of hemolytic anemia requiring blood transfusions, pain crises, and organ damage. Since the first description of the irregular sickle-shaped red blood cells (RBCs) more than 100 years ago, our understanding of the disease has evolved tremendously. Recent advances in the field, more so within the last three decades, have alleviated symptoms for countless patients, especially in high-income countries. Although there is evidence of several important therapies in the pipeline, greater investment in research is needed into both of these therapies and the dissemination of effective care to the affected population, especially because of historical mistrust. In this book, we present an overview of sickle cell disease, pathogenesis, clinical presentation, complications, and recent treatment modalities and prospective research that will enable the reader to get a better understanding of this hot topic. |
| format | Online |
| id | doab-20.500.12854ir-146539 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1465392024-10-25T10:53:20Z Current Practices in Sickle Cell Disease Zakaria, Marwa Haematology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJF Haematology Sickle cell anemia is an inherited disorder of the globin chains that causes hemolysis and chronic organ damage. Sickle cell anemia is the most common form of sickle cell disease (SCD), with a lifelong affliction of hemolytic anemia requiring blood transfusions, pain crises, and organ damage. Since the first description of the irregular sickle-shaped red blood cells (RBCs) more than 100 years ago, our understanding of the disease has evolved tremendously. Recent advances in the field, more so within the last three decades, have alleviated symptoms for countless patients, especially in high-income countries. Although there is evidence of several important therapies in the pipeline, greater investment in research is needed into both of these therapies and the dissemination of effective care to the affected population, especially because of historical mistrust. In this book, we present an overview of sickle cell disease, pathogenesis, clinical presentation, complications, and recent treatment modalities and prospective research that will enable the reader to get a better understanding of this hot topic. 2024-10-25T10:53:17Z 2024-10-25T10:53:17Z 2024 book ONIX_20241025_9780854669196_81 9780854669196 9780854669202 9780854669219 https://directory.doabooks.org/handle/20.500.12854/146539 eng image/jpeg n/a https://www.intechopen.com/books/1002959 https://intech-files.s3.amazonaws.com/a043Y00000yuj6MQAQ/0014863_Authors_Book%20%282024-09-19%2010%3A35%3A27%29.pdf IntechOpen IntechOpen 10.5772/intechopen.110970 10.5772/intechopen.110970 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9780854669196 9780854669202 9780854669219 IntechOpen 136 open access |
| spellingShingle | Haematology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJF Haematology Current Practices in Sickle Cell Disease |
| title | Current Practices in Sickle Cell Disease |
| title_full | Current Practices in Sickle Cell Disease |
| title_fullStr | Current Practices in Sickle Cell Disease |
| title_full_unstemmed | Current Practices in Sickle Cell Disease |
| title_short | Current Practices in Sickle Cell Disease |
| title_sort | current practices in sickle cell disease |
| topic | Haematology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJF Haematology |
| topic_facet | Haematology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJF Haematology |
| url | ONIX_20241025_9780854669196_81 |