May We Make the World?
An in-depth look at genetic alteration in the natural world and the oppositions to it, seen through the case study of a gene drive for malaria.May We Make the World? is an engaging reflection on the history, nature, goal, and meaning of using a new technological idea—CRISPR-based genetic engineering...
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| Հիմնական հեղինակ: | |
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| Ձևաչափ: | Online |
| Լեզու: | անգլերեն |
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The MIT Press
2024
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| Խորագրեր: | |
| Առցանց հասանելիություն: | ONIX_20241025_9780262376990_98 |
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Չկան պիտակներ, Եղեք առաջինը, ով նշում է այս գրառումը!
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| _version_ | 1869531419626176512 |
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| author | Zoloth, Laurie |
| author_browse | Zoloth, Laurie |
| author_facet | Zoloth, Laurie |
| author_sort | Zoloth, Laurie |
| collection | Directory of Open Access Books |
| description | An in-depth look at genetic alteration in the natural world and the oppositions to it, seen through the case study of a gene drive for malaria.May We Make the World? is an engaging reflection on the history, nature, goal, and meaning of using a new technological idea—CRISPR-based genetic engineering—to alter the genome of the mosquito that carries malaria. This technology, called a “gene drive,” can alter the sex ratio in Anopheles gambiae mosquitoes, the key vector for falciparum, the deadliest form of malaria. P. Falciparum kills 400,000 people a year, largely the poorest children in the world among them. In her sobering examination of the issue, Laurie Zoloth considers the leading ethical arguments for and against gene drives, explores the regulatory efforts that have emerged long in advance of the science, and considers the philosophical questions raised by the struggle to eliminate malaria. The development of a gene drive for malaria will have far-reaching implications for it represents the first use of genetic engineering in the natural world and the first creation of a genetic variant intended to spread in the African wild beyond human control. Drawing on two decades of work, Zoloth brilliantly argues that we can understand the complex moral issues at stake only by carefully reflecting on the science, the nature of the local and global discourse about genetic engineering, and the long history of malaria, which—as it transformed from a worldwide disease to a tropical one—reshaped the world as we know it. |
| format | Online |
| id | doab-20.500.12854ir-146720 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | The MIT Press |
| publisherStr | The MIT Press |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1467202024-10-25T13:18:21Z May We Make the World? Zoloth, Laurie Philosophy/Ethics & Bioethics Biomedical Sciences/General thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNH Personal and public health / health education::MBNH2 Environmental factors thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDT Topics in philosophy::QDTQ Ethics and moral philosophy thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKZ Therapy and therapeutics::MKZV Gene therapy An in-depth look at genetic alteration in the natural world and the oppositions to it, seen through the case study of a gene drive for malaria.May We Make the World? is an engaging reflection on the history, nature, goal, and meaning of using a new technological idea—CRISPR-based genetic engineering—to alter the genome of the mosquito that carries malaria. This technology, called a “gene drive,” can alter the sex ratio in Anopheles gambiae mosquitoes, the key vector for falciparum, the deadliest form of malaria. P. Falciparum kills 400,000 people a year, largely the poorest children in the world among them. In her sobering examination of the issue, Laurie Zoloth considers the leading ethical arguments for and against gene drives, explores the regulatory efforts that have emerged long in advance of the science, and considers the philosophical questions raised by the struggle to eliminate malaria. The development of a gene drive for malaria will have far-reaching implications for it represents the first use of genetic engineering in the natural world and the first creation of a genetic variant intended to spread in the African wild beyond human control. Drawing on two decades of work, Zoloth brilliantly argues that we can understand the complex moral issues at stake only by carefully reflecting on the science, the nature of the local and global discourse about genetic engineering, and the long history of malaria, which—as it transformed from a worldwide disease to a tropical one—reshaped the world as we know it. 2024-10-25T13:18:19Z 2024-10-25T13:18:19Z 2023 book ONIX_20241025_9780262376990_98 9780262376990 9780262546980 https://directory.doabooks.org/handle/20.500.12854/146720 eng Basic Bioethics image/jpeg n/a https://doi.org/10.7551/mitpress/15043.001.0001 The MIT Press The MIT Press 10.7551/mitpress/15043.001.0001 10.7551/mitpress/15043.001.0001 ae0cf962-f685-4933-93d1-916defa5123d 9780262376990 9780262546980 The MIT Press 428 Cambridge open access |
| spellingShingle | Philosophy/Ethics & Bioethics Biomedical Sciences/General thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNH Personal and public health / health education::MBNH2 Environmental factors thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDT Topics in philosophy::QDTQ Ethics and moral philosophy thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKZ Therapy and therapeutics::MKZV Gene therapy Zoloth, Laurie May We Make the World? |
| title | May We Make the World? |
| title_full | May We Make the World? |
| title_fullStr | May We Make the World? |
| title_full_unstemmed | May We Make the World? |
| title_short | May We Make the World? |
| title_sort | may we make the world |
| topic | Philosophy/Ethics & Bioethics Biomedical Sciences/General thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNH Personal and public health / health education::MBNH2 Environmental factors thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDT Topics in philosophy::QDTQ Ethics and moral philosophy thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKZ Therapy and therapeutics::MKZV Gene therapy |
| topic_facet | Philosophy/Ethics & Bioethics Biomedical Sciences/General thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNH Personal and public health / health education::MBNH2 Environmental factors thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDT Topics in philosophy::QDTQ Ethics and moral philosophy thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKZ Therapy and therapeutics::MKZV Gene therapy |
| url | ONIX_20241025_9780262376990_98 |
| work_keys_str_mv | AT zolothlaurie maywemaketheworld |