COVID-19 as a Model for PCR Viral Respiratory Disease Diagnostics

The COVID-19 pandemic has affected the whole world and influenced almost all areas of human life. Although each country has approached the situation differently, they had one activity in common – the effort to slow down the spread of the virus to prevent an overload of national health systems. The p...

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Main Authors: Pohludka, Michal, Piherová, Lenka
Format: Online
Sprog:engelsk
Udgivet: Karolinum Press 2025
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Online adgang:https://directory.doabooks.org/handle/20.500.12854/149565
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author Pohludka, Michal
Piherová, Lenka
author_browse Piherová, Lenka
Pohludka, Michal
author_facet Pohludka, Michal
Piherová, Lenka
author_sort Pohludka, Michal
collection Directory of Open Access Books
description The COVID-19 pandemic has affected the whole world and influenced almost all areas of human life. Although each country has approached the situation differently, they had one activity in common – the effort to slow down the spread of the virus to prevent an overload of national health systems. The preferred testing method for medical diagnostics as well as for elimination of the spread within the population is the Real-Time Quantitative Reverse Transcription PCR (RT-qPCR). In this book, we focus in detail on the methodology, good practice, and troubleshooting. The aim of the publication is to provide a practical advanced manual that can be utilized in any diagnostic laboratory using the PCR method. Good practice in laboratory diagnostics is essential for medical as well as for epidemiological reasons. During an epidemic outbreak, laboratory diagnostics helps physicians to treat patients effectively and the laboratory big data provides information about the spread of the virus in different sociological groups. This is illustrated in the presented experiment studying spread of the virus in a child population at schools.
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spelling doab-20.500.12854ir-1495652025-01-10T09:54:55Z COVID-19 as a Model for PCR Viral Respiratory Disease Diagnostics Pohludka, Michal Piherová, Lenka COVID-19 pandemic medical diagnostics respiratory disease PCR diagnostics virus SARS-CoV-2 testing method methodology child population thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases::MJCJ4 Human coronaviruses The COVID-19 pandemic has affected the whole world and influenced almost all areas of human life. Although each country has approached the situation differently, they had one activity in common – the effort to slow down the spread of the virus to prevent an overload of national health systems. The preferred testing method for medical diagnostics as well as for elimination of the spread within the population is the Real-Time Quantitative Reverse Transcription PCR (RT-qPCR). In this book, we focus in detail on the methodology, good practice, and troubleshooting. The aim of the publication is to provide a practical advanced manual that can be utilized in any diagnostic laboratory using the PCR method. Good practice in laboratory diagnostics is essential for medical as well as for epidemiological reasons. During an epidemic outbreak, laboratory diagnostics helps physicians to treat patients effectively and the laboratory big data provides information about the spread of the virus in different sociological groups. This is illustrated in the presented experiment studying spread of the virus in a child population at schools. Published 2025-01-10T09:54:52Z 2025-01-10T09:54:52Z 2024-09 book 9788024659497 9788024659855 https://directory.doabooks.org/handle/20.500.12854/149565 eng image/jpeg Attribution 4.0 International https://karolinum.cz/knihy/pohludka-covid-19-as-a-model-for-pcr-viral-respiratory-disease-diagnostics-30642 https://dspace.cuni.cz/bitstream/handle/20.500.11956/195518/9788024659855.pdf Karolinum Press 10.14712/9788024659855 10.14712/9788024659855 8d94c6aa-2a71-4559-9698-bf3e883a574a 9788024659497 9788024659855 72 Prague open access
spellingShingle COVID-19
pandemic
medical diagnostics
respiratory disease
PCR diagnostics
virus
SARS-CoV-2
testing method
methodology
child population
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases::MJCJ4 Human coronaviruses
Pohludka, Michal
Piherová, Lenka
COVID-19 as a Model for PCR Viral Respiratory Disease Diagnostics
title COVID-19 as a Model for PCR Viral Respiratory Disease Diagnostics
title_full COVID-19 as a Model for PCR Viral Respiratory Disease Diagnostics
title_fullStr COVID-19 as a Model for PCR Viral Respiratory Disease Diagnostics
title_full_unstemmed COVID-19 as a Model for PCR Viral Respiratory Disease Diagnostics
title_short COVID-19 as a Model for PCR Viral Respiratory Disease Diagnostics
title_sort covid 19 as a model for pcr viral respiratory disease diagnostics
topic COVID-19
pandemic
medical diagnostics
respiratory disease
PCR diagnostics
virus
SARS-CoV-2
testing method
methodology
child population
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases::MJCJ4 Human coronaviruses
topic_facet COVID-19
pandemic
medical diagnostics
respiratory disease
PCR diagnostics
virus
SARS-CoV-2
testing method
methodology
child population
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases::MJCJ4 Human coronaviruses
url https://directory.doabooks.org/handle/20.500.12854/149565
work_keys_str_mv AT pohludkamichal covid19asamodelforpcrviralrespiratorydiseasediagnostics
AT piherovalenka covid19asamodelforpcrviralrespiratorydiseasediagnostics