The Role of NRF2 Transcription Factor
The regulation of the transcription factor NRF2 opens a therapeutic window for a host of chronic degenerative diseases, such as diabetes and its complications, cancer, obesity, neurodegenerative diseases, kidney diseases, immunological diseases, and so on. The ability to regulate cytoprotective func...
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| Format: | Online |
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| Sprog: | engelsk |
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IntechOpen
2025
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| Online adgang: | ONIX_20250220_9780854669912_113 |
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| collection | Directory of Open Access Books |
| description | The regulation of the transcription factor NRF2 opens a therapeutic window for a host of chronic degenerative diseases, such as diabetes and its complications, cancer, obesity, neurodegenerative diseases, kidney diseases, immunological diseases, and so on. The ability to regulate cytoprotective functions such as antioxidant defenses or pro-apoptotic or anti-apoptotic functions is of utmost importance. Currently, there are therapeutic agents to activate or inhibit NRF2; research should focus on understanding how NRF2 makes “the decision” to perform one function or another. |
| format | Online |
| id | doab-20.500.12854ir-152596 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1525962025-02-20T08:19:31Z The Role of NRF2 Transcription Factor Antonio Morales-Gonzalez, José Osiris Madrigal-Santillan, Eduardo Soriano-Ursúa, Marvin A. Morales-González, Ángel thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry The regulation of the transcription factor NRF2 opens a therapeutic window for a host of chronic degenerative diseases, such as diabetes and its complications, cancer, obesity, neurodegenerative diseases, kidney diseases, immunological diseases, and so on. The ability to regulate cytoprotective functions such as antioxidant defenses or pro-apoptotic or anti-apoptotic functions is of utmost importance. Currently, there are therapeutic agents to activate or inhibit NRF2; research should focus on understanding how NRF2 makes “the decision” to perform one function or another. 2025-02-20T08:19:28Z 2025-02-20T08:19:28Z 2024 book ONIX_20250220_9780854669912_113 2632-0983 9780854669912 9780854669929 9780854669936 https://directory.doabooks.org/handle/20.500.12854/152596 eng Biochemistry image/jpeg n/a https://www.intechopen.com/books/1003596 https://intech-files.s3.amazonaws.com/a043Y000010KLtVQAW/0015500_Authors_Book%20%282024-12-05%2008%3A36%3A39%29.pdf IntechOpen IntechOpen 10.5772/intechopen.111702 10.5772/intechopen.111702 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9780854669912 9780854669929 9780854669936 IntechOpen 57 124 open access |
| spellingShingle | thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry The Role of NRF2 Transcription Factor |
| title | The Role of NRF2 Transcription Factor |
| title_full | The Role of NRF2 Transcription Factor |
| title_fullStr | The Role of NRF2 Transcription Factor |
| title_full_unstemmed | The Role of NRF2 Transcription Factor |
| title_short | The Role of NRF2 Transcription Factor |
| title_sort | role of nrf2 transcription factor |
| topic | thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry |
| topic_facet | thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry |
| url | ONIX_20250220_9780854669912_113 |