Recent Advances in the Discovery of Novel Drugs on Natural Molecules
Drug discovery is still one of the fundamental pillars of modern medicine; the urgency in seeking new natural compounds or reusing old drugs for new therapeutic solutions is always a current topic. Since most compounds exhibit synergistic effects or share multiple targets, traditional approaches to...
Zapisane w:
| Format: | Online |
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| Język: | angielski |
| Wydane: |
MDPI - Multidisciplinary Digital Publishing Institute
2025
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| Hasła przedmiotowe: | |
| Dostęp online: | ONIX_20250220_9783725818730_38 |
| Etykiety: |
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| _version_ | 1869527077641781248 |
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| collection | Directory of Open Access Books |
| description | Drug discovery is still one of the fundamental pillars of modern medicine; the urgency in seeking new natural compounds or reusing old drugs for new therapeutic solutions is always a current topic. Since most compounds exhibit synergistic effects or share multiple targets, traditional approaches to finding potential drug candidates can reduce their therapeutic efficacy. As a result, new techniques are required to produce drugs with high and multi-target activity as well as improved bioavailability. In this regard, the application of multidisciplinary approaches, bioinformatics, data mining, pathway refactoring, cell factories, metabolomics, and computational chemistry, allows for the revelation of novel drug molecules from microbial strains or bioresources that might otherwise escape notice when using classical top-down strategies. The collection of articles in this book covers key topics related to the discovery of new natural molecules with biological activity; the herein collected studies open new pathways toward the more efficient and targeted enhancement of natural compounds for drug development. |
| format | Online |
| id | doab-20.500.12854ir-152674 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1526742025-02-20T12:53:32Z Recent Advances in the Discovery of Novel Drugs on Natural Molecules Quintieri, Laura Caputo, Leonardo Nicolotti, Orazio natural products polyphenols peptides computational chemistry molecular biology metabolomics drug discovery thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MN Surgery Drug discovery is still one of the fundamental pillars of modern medicine; the urgency in seeking new natural compounds or reusing old drugs for new therapeutic solutions is always a current topic. Since most compounds exhibit synergistic effects or share multiple targets, traditional approaches to finding potential drug candidates can reduce their therapeutic efficacy. As a result, new techniques are required to produce drugs with high and multi-target activity as well as improved bioavailability. In this regard, the application of multidisciplinary approaches, bioinformatics, data mining, pathway refactoring, cell factories, metabolomics, and computational chemistry, allows for the revelation of novel drug molecules from microbial strains or bioresources that might otherwise escape notice when using classical top-down strategies. The collection of articles in this book covers key topics related to the discovery of new natural molecules with biological activity; the herein collected studies open new pathways toward the more efficient and targeted enhancement of natural compounds for drug development. 2025-02-20T12:53:30Z 2025-02-20T12:53:30Z 2024 book ONIX_20250220_9783725818730_38 9783725818730 9783725818747 https://directory.doabooks.org/handle/20.500.12854/152674 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/10165 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-1874-7 10.3390/books978-3-7258-1874-7 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725818730 9783725818747 376 Basel open access |
| spellingShingle | natural products polyphenols peptides computational chemistry molecular biology metabolomics drug discovery thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MN Surgery Recent Advances in the Discovery of Novel Drugs on Natural Molecules |
| title | Recent Advances in the Discovery of Novel Drugs on Natural Molecules |
| title_full | Recent Advances in the Discovery of Novel Drugs on Natural Molecules |
| title_fullStr | Recent Advances in the Discovery of Novel Drugs on Natural Molecules |
| title_full_unstemmed | Recent Advances in the Discovery of Novel Drugs on Natural Molecules |
| title_short | Recent Advances in the Discovery of Novel Drugs on Natural Molecules |
| title_sort | recent advances in the discovery of novel drugs on natural molecules |
| topic | natural products polyphenols peptides computational chemistry molecular biology metabolomics drug discovery thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MN Surgery |
| topic_facet | natural products polyphenols peptides computational chemistry molecular biology metabolomics drug discovery thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MN Surgery |
| url | ONIX_20250220_9783725818730_38 |