Psoriasis and Psoriatic Arthritis

Psoriasis with psoriatic arthritis is a chronic and difficult-to-treat inflammatory skin condition. Recent developments in biology, immunology, and molecular biology have enabled us to use various targeted therapeutics in treating these conditions, such as biologics and small-molecule inhibitors. Th...

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collection Directory of Open Access Books
description Psoriasis with psoriatic arthritis is a chronic and difficult-to-treat inflammatory skin condition. Recent developments in biology, immunology, and molecular biology have enabled us to use various targeted therapeutics in treating these conditions, such as biologics and small-molecule inhibitors. The enhanced speed at which translational research is developing in this field has led to the production of many biologics technologies and small-molecule inhibitors, but a complete cure for this condition has not yet been accomplished. In light of this, understanding the pathophysiology of these conditions is crucial and would allow us to carefully recognize which patients need to be treated earlier in order to improve patients’ quality of life. This Special Issue is composed of discussions on the pathophysiology of psoriasis with psoriatic arthritis, including infiltrating effector T-cells, regulatory T-cells, dendritic cells, monocytes, and macrophages; the treatment of psoriasis with psoriatic arthritis, including biologics, small-molecule inhibitors, and topical treatments; and the quality of life of patients with this condition, which includes the introduction of treatment goals and the treat-to-target concept.
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publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-1526752025-02-20T12:53:38Z Psoriasis and Psoriatic Arthritis Komine, Mayumi psoriasis COVID-19 SARS-CoV-2 systemic therapy biologics inflammatory skin disease Th17 cells adipokines glycoproteins fatty acid-binding protein skin-resident memory T cells human cytokines autoantigens treatment regulatory T cell forkhead box protein 3 short chain fatty acid butyrate interleukin-17A interleukin-23 dendritic cell gut microbiome Janus kinases therapy calcipotriol betamethasone dipropionate long-term treatment nail psoriasis proactive treatment topical therapy scalp psoriasis vitamin D3 derivatives BMDCs IL-23 IL-36γ metformin psoriatic arthritis assessment disease activity composite disease activity measures patient-reported outcomes cross-sectional studies health care surveys Japan treatment goal biological drugs anti-TNF-α anti-IL-17 anti-IL-12/23 adherence persistence early diagnosis early intervention female sex hormone estrogen progesterone thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MN Surgery Psoriasis with psoriatic arthritis is a chronic and difficult-to-treat inflammatory skin condition. Recent developments in biology, immunology, and molecular biology have enabled us to use various targeted therapeutics in treating these conditions, such as biologics and small-molecule inhibitors. The enhanced speed at which translational research is developing in this field has led to the production of many biologics technologies and small-molecule inhibitors, but a complete cure for this condition has not yet been accomplished. In light of this, understanding the pathophysiology of these conditions is crucial and would allow us to carefully recognize which patients need to be treated earlier in order to improve patients’ quality of life. This Special Issue is composed of discussions on the pathophysiology of psoriasis with psoriatic arthritis, including infiltrating effector T-cells, regulatory T-cells, dendritic cells, monocytes, and macrophages; the treatment of psoriasis with psoriatic arthritis, including biologics, small-molecule inhibitors, and topical treatments; and the quality of life of patients with this condition, which includes the introduction of treatment goals and the treat-to-target concept. 2025-02-20T12:53:35Z 2025-02-20T12:53:35Z 2024 book ONIX_20250220_9783725818792_39 9783725818792 9783725818808 https://directory.doabooks.org/handle/20.500.12854/152675 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/9794 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-1880-8 10.3390/books978-3-7258-1880-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725818792 9783725818808 166 Basel open access
spellingShingle psoriasis
COVID-19
SARS-CoV-2
systemic therapy
biologics
inflammatory skin disease
Th17 cells
adipokines
glycoproteins
fatty acid-binding protein
skin-resident memory T cells
human
cytokines
autoantigens
treatment
regulatory T cell
forkhead box protein 3
short chain fatty acid
butyrate
interleukin-17A
interleukin-23
dendritic cell
gut microbiome
Janus kinases
therapy
calcipotriol
betamethasone dipropionate
long-term treatment
nail psoriasis
proactive treatment
topical therapy
scalp psoriasis
vitamin D3 derivatives
BMDCs
IL-23
IL-36γ
metformin
psoriatic arthritis
assessment
disease activity
composite disease activity measures
patient-reported outcomes
cross-sectional studies
health care surveys
Japan
treatment goal
biological drugs
anti-TNF-α
anti-IL-17
anti-IL-12/23
adherence
persistence
early diagnosis
early intervention
female sex hormone
estrogen
progesterone
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MN Surgery
Psoriasis and Psoriatic Arthritis
title Psoriasis and Psoriatic Arthritis
title_full Psoriasis and Psoriatic Arthritis
title_fullStr Psoriasis and Psoriatic Arthritis
title_full_unstemmed Psoriasis and Psoriatic Arthritis
title_short Psoriasis and Psoriatic Arthritis
title_sort psoriasis and psoriatic arthritis
topic psoriasis
COVID-19
SARS-CoV-2
systemic therapy
biologics
inflammatory skin disease
Th17 cells
adipokines
glycoproteins
fatty acid-binding protein
skin-resident memory T cells
human
cytokines
autoantigens
treatment
regulatory T cell
forkhead box protein 3
short chain fatty acid
butyrate
interleukin-17A
interleukin-23
dendritic cell
gut microbiome
Janus kinases
therapy
calcipotriol
betamethasone dipropionate
long-term treatment
nail psoriasis
proactive treatment
topical therapy
scalp psoriasis
vitamin D3 derivatives
BMDCs
IL-23
IL-36γ
metformin
psoriatic arthritis
assessment
disease activity
composite disease activity measures
patient-reported outcomes
cross-sectional studies
health care surveys
Japan
treatment goal
biological drugs
anti-TNF-α
anti-IL-17
anti-IL-12/23
adherence
persistence
early diagnosis
early intervention
female sex hormone
estrogen
progesterone
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MN Surgery
topic_facet psoriasis
COVID-19
SARS-CoV-2
systemic therapy
biologics
inflammatory skin disease
Th17 cells
adipokines
glycoproteins
fatty acid-binding protein
skin-resident memory T cells
human
cytokines
autoantigens
treatment
regulatory T cell
forkhead box protein 3
short chain fatty acid
butyrate
interleukin-17A
interleukin-23
dendritic cell
gut microbiome
Janus kinases
therapy
calcipotriol
betamethasone dipropionate
long-term treatment
nail psoriasis
proactive treatment
topical therapy
scalp psoriasis
vitamin D3 derivatives
BMDCs
IL-23
IL-36γ
metformin
psoriatic arthritis
assessment
disease activity
composite disease activity measures
patient-reported outcomes
cross-sectional studies
health care surveys
Japan
treatment goal
biological drugs
anti-TNF-α
anti-IL-17
anti-IL-12/23
adherence
persistence
early diagnosis
early intervention
female sex hormone
estrogen
progesterone
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MN Surgery
url ONIX_20250220_9783725818792_39