Recent Advances in Pathophysiology and Therapeutic Approaches in Epilepsy
Epilepsy is a widespread neurological disorder that affects around 70 million people worldwide. The main characteristic of this neurological disorder is the occurrence of unexpected and recurrent seizures. The cure for and management of epilepsy are confined to treating symptoms but do not modify th...
Sparad:
| Materialtyp: | Online |
|---|---|
| Språk: | engelska |
| Utgiven: |
MDPI - Multidisciplinary Digital Publishing Institute
2025
|
| Ämnen: | |
| Länkar: | ONIX_20250220_9783725821822_153 |
| Taggar: |
Inga taggar, Lägg till första taggen!
|
| _version_ | 1869517141286322176 |
|---|---|
| collection | Directory of Open Access Books |
| description | Epilepsy is a widespread neurological disorder that affects around 70 million people worldwide. The main characteristic of this neurological disorder is the occurrence of unexpected and recurrent seizures. The cure for and management of epilepsy are confined to treating symptoms but do not modify the development and progression of the disease. Furthermore, among the people who are taking antiseizure medicines, more than 30% of them still have epilepsy, and long-term use of these drugs can result in a variety of side effects. Hence, there is an urgent need to understand the detailed pathophysiology and mechanism of the development of diverse forms of epilepsy as well as identify crucial therapeutic targets. Moreover, finetuning as well as examining the effectiveness of several surgical procedures and neuromodulation methods to treat drug-resistant epilepsy are also required.This Special Issue features original research and review articles by experts discussing the recent developments in the pathophysiology, risk factors and possible treatment options in diverse forms of epilepsy. |
| format | Online |
| id | doab-20.500.12854ir-152789 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1527892025-02-20T13:04:18Z Recent Advances in Pathophysiology and Therapeutic Approaches in Epilepsy Prakash, Chandra Sharma, Deepak Kumar, Pavan drug-resistant epilepsy children resection surgery palliative surgery seizure outcome epilepsy seizures inflammation anti-inflammatory response flavonoids dehydroepiandrosterone neuronal loss astroglial activation dendritic degeneration oxidative stress mitochondrial dysfunction antioxidants antiepileptic drugs antiseizure medications neuromodulation keto diet nutrients hemispherotomy surgical procedure daytime-restricted feeding status epilepticus Nrf2 SOD2 hippocampus super-refractory status epilepticus electroconvulsive therapy deep brain stimulation vagus nerve stimulation children epilepsy IED and cognition visuo-spatial skills EEG score transition readiness psychological parents network resection ablation invasive monitoring sEEG epileptic syndromes neurotransmission comorbidities clinical trials animal epilepsy models interictal spiking therapeutic epileptiform activities n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Epilepsy is a widespread neurological disorder that affects around 70 million people worldwide. The main characteristic of this neurological disorder is the occurrence of unexpected and recurrent seizures. The cure for and management of epilepsy are confined to treating symptoms but do not modify the development and progression of the disease. Furthermore, among the people who are taking antiseizure medicines, more than 30% of them still have epilepsy, and long-term use of these drugs can result in a variety of side effects. Hence, there is an urgent need to understand the detailed pathophysiology and mechanism of the development of diverse forms of epilepsy as well as identify crucial therapeutic targets. Moreover, finetuning as well as examining the effectiveness of several surgical procedures and neuromodulation methods to treat drug-resistant epilepsy are also required.This Special Issue features original research and review articles by experts discussing the recent developments in the pathophysiology, risk factors and possible treatment options in diverse forms of epilepsy. 2025-02-20T13:04:16Z 2025-02-20T13:04:16Z 2024 book ONIX_20250220_9783725821822_153 9783725821822 9783725821815 https://directory.doabooks.org/handle/20.500.12854/152789 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/9945 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-2181-5 10.3390/books978-3-7258-2181-5 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725821822 9783725821815 212 Basel open access |
| spellingShingle | drug-resistant epilepsy children resection surgery palliative surgery seizure outcome epilepsy seizures inflammation anti-inflammatory response flavonoids dehydroepiandrosterone neuronal loss astroglial activation dendritic degeneration oxidative stress mitochondrial dysfunction antioxidants antiepileptic drugs antiseizure medications neuromodulation keto diet nutrients hemispherotomy surgical procedure daytime-restricted feeding status epilepticus Nrf2 SOD2 hippocampus super-refractory status epilepticus electroconvulsive therapy deep brain stimulation vagus nerve stimulation children epilepsy IED and cognition visuo-spatial skills EEG score transition readiness psychological parents network resection ablation invasive monitoring sEEG epileptic syndromes neurotransmission comorbidities clinical trials animal epilepsy models interictal spiking therapeutic epileptiform activities n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Recent Advances in Pathophysiology and Therapeutic Approaches in Epilepsy |
| title | Recent Advances in Pathophysiology and Therapeutic Approaches in Epilepsy |
| title_full | Recent Advances in Pathophysiology and Therapeutic Approaches in Epilepsy |
| title_fullStr | Recent Advances in Pathophysiology and Therapeutic Approaches in Epilepsy |
| title_full_unstemmed | Recent Advances in Pathophysiology and Therapeutic Approaches in Epilepsy |
| title_short | Recent Advances in Pathophysiology and Therapeutic Approaches in Epilepsy |
| title_sort | recent advances in pathophysiology and therapeutic approaches in epilepsy |
| topic | drug-resistant epilepsy children resection surgery palliative surgery seizure outcome epilepsy seizures inflammation anti-inflammatory response flavonoids dehydroepiandrosterone neuronal loss astroglial activation dendritic degeneration oxidative stress mitochondrial dysfunction antioxidants antiepileptic drugs antiseizure medications neuromodulation keto diet nutrients hemispherotomy surgical procedure daytime-restricted feeding status epilepticus Nrf2 SOD2 hippocampus super-refractory status epilepticus electroconvulsive therapy deep brain stimulation vagus nerve stimulation children epilepsy IED and cognition visuo-spatial skills EEG score transition readiness psychological parents network resection ablation invasive monitoring sEEG epileptic syndromes neurotransmission comorbidities clinical trials animal epilepsy models interictal spiking therapeutic epileptiform activities n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| topic_facet | drug-resistant epilepsy children resection surgery palliative surgery seizure outcome epilepsy seizures inflammation anti-inflammatory response flavonoids dehydroepiandrosterone neuronal loss astroglial activation dendritic degeneration oxidative stress mitochondrial dysfunction antioxidants antiepileptic drugs antiseizure medications neuromodulation keto diet nutrients hemispherotomy surgical procedure daytime-restricted feeding status epilepticus Nrf2 SOD2 hippocampus super-refractory status epilepticus electroconvulsive therapy deep brain stimulation vagus nerve stimulation children epilepsy IED and cognition visuo-spatial skills EEG score transition readiness psychological parents network resection ablation invasive monitoring sEEG epileptic syndromes neurotransmission comorbidities clinical trials animal epilepsy models interictal spiking therapeutic epileptiform activities n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| url | ONIX_20250220_9783725821822_153 |