Novel Therapies of Oxidative Stress-Induced Age-Related Neurodegenerative Diseases

This Special Issue aims to address several important questions regarding the relationship between neurodegenerative disorders and oxidative stress: First, (i) is the process of neurodegeneration a “one-way ticket” to neuronal death, programmed early in life? And second, (ii) can it be prevented by n...

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অনলাইন ব্যবহার করুন:ONIX_20250220_9783725822256_171
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collection Directory of Open Access Books
description This Special Issue aims to address several important questions regarding the relationship between neurodegenerative disorders and oxidative stress: First, (i) is the process of neurodegeneration a “one-way ticket” to neuronal death, programmed early in life? And second, (ii) can it be prevented by neuroprotective interventions? The growing body of literature on nutraceuticals, nutrigenomics, and nutrigenetics demonstrates their promise as powerful neuroprotectors for future novel therapies that naturally enhance antioxidant capacity. Furthermore, different active compounds that target oxidative stress prove their efficiency. In this Special Issue, experts in the field share their research findings and review the latest findings in the field of neurodegenerative disorder interventions and disease mechanisms. With this collection of articles, we provide some future direction for clinicians and patients dealing with neurodegenerative diseases.
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language eng
publishDate 2025
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publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
record_format ojs
spelling doab-20.500.12854ir-1528072025-02-20T13:06:13Z Novel Therapies of Oxidative Stress-Induced Age-Related Neurodegenerative Diseases Buga, Ana-Maria Oancea, Carmen Nicoleta vitamin C ascorbic acid subventricular zone lateral ventricle extensions adult neurogenesis stroke stem cell mitochondria oxidation neuroinflammation reactive oxygen species age-related macular degeneration D. tuberculatus A2E antioxidant oxidative stress inflammatory response dopamine Parkinson’s disease neuromelanin antioxidants aminochrome glutathione transferase M2-2 DT-diaphorase ferroptosis KEAP1/NRF2 dopaminergic neurons older adults normal aging physical activity neurodegenerative pathology aging redox potential ALS wobbler mice liver hippocampus cerebellum glutamate cysteine ligase (GCL) glutathione synthetase (GSS) multidrug resistance protein (MRP) gamma-glutamyl transpeptidase (GGT) neuroprotection Piper nigrum H2O2-induced stress anti-acetylcholine esterase activity anti-glycation green tea EGCG glaucoma retinal ganglion cells anti-oxidation anti-inflammation Alzheimer’s disease dementia sclerosis schizophrenia ataxia therapy brain cancers NRF2 AHR heme oxygenase n/a astrocytes vascular endothelial cells glutathione nitric oxide oxidants disease progression thema EDItEUR::M Medicine and Nursing thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences This Special Issue aims to address several important questions regarding the relationship between neurodegenerative disorders and oxidative stress: First, (i) is the process of neurodegeneration a “one-way ticket” to neuronal death, programmed early in life? And second, (ii) can it be prevented by neuroprotective interventions? The growing body of literature on nutraceuticals, nutrigenomics, and nutrigenetics demonstrates their promise as powerful neuroprotectors for future novel therapies that naturally enhance antioxidant capacity. Furthermore, different active compounds that target oxidative stress prove their efficiency. In this Special Issue, experts in the field share their research findings and review the latest findings in the field of neurodegenerative disorder interventions and disease mechanisms. With this collection of articles, we provide some future direction for clinicians and patients dealing with neurodegenerative diseases. 2025-02-20T13:06:09Z 2025-02-20T13:06:09Z 2024 book ONIX_20250220_9783725822256_171 9783725822256 9783725822263 https://directory.doabooks.org/handle/20.500.12854/152807 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/9963 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-2226-3 10.3390/books978-3-7258-2226-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725822256 9783725822263 220 Basel open access
spellingShingle vitamin C
ascorbic acid
subventricular zone
lateral ventricle extensions
adult neurogenesis
stroke
stem cell
mitochondria
oxidation
neuroinflammation
reactive oxygen species
age-related macular degeneration
D. tuberculatus
A2E
antioxidant
oxidative stress
inflammatory response
dopamine
Parkinson’s disease
neuromelanin
antioxidants
aminochrome
glutathione transferase M2-2
DT-diaphorase
ferroptosis
KEAP1/NRF2
dopaminergic neurons
older adults
normal aging
physical activity
neurodegenerative pathology aging
redox potential
ALS
wobbler mice
liver
hippocampus
cerebellum
glutamate cysteine ligase (GCL)
glutathione synthetase (GSS)
multidrug resistance protein (MRP)
gamma-glutamyl transpeptidase (GGT)
neuroprotection
Piper nigrum
H2O2-induced stress
anti-acetylcholine esterase activity
anti-glycation
green tea
EGCG
glaucoma
retinal ganglion cells
anti-oxidation
anti-inflammation
Alzheimer’s disease
dementia
sclerosis
schizophrenia
ataxia
therapy
brain cancers
NRF2
AHR
heme oxygenase
n/a
astrocytes
vascular endothelial cells
glutathione
nitric oxide
oxidants
disease progression
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
Novel Therapies of Oxidative Stress-Induced Age-Related Neurodegenerative Diseases
title Novel Therapies of Oxidative Stress-Induced Age-Related Neurodegenerative Diseases
title_full Novel Therapies of Oxidative Stress-Induced Age-Related Neurodegenerative Diseases
title_fullStr Novel Therapies of Oxidative Stress-Induced Age-Related Neurodegenerative Diseases
title_full_unstemmed Novel Therapies of Oxidative Stress-Induced Age-Related Neurodegenerative Diseases
title_short Novel Therapies of Oxidative Stress-Induced Age-Related Neurodegenerative Diseases
title_sort novel therapies of oxidative stress induced age related neurodegenerative diseases
topic vitamin C
ascorbic acid
subventricular zone
lateral ventricle extensions
adult neurogenesis
stroke
stem cell
mitochondria
oxidation
neuroinflammation
reactive oxygen species
age-related macular degeneration
D. tuberculatus
A2E
antioxidant
oxidative stress
inflammatory response
dopamine
Parkinson’s disease
neuromelanin
antioxidants
aminochrome
glutathione transferase M2-2
DT-diaphorase
ferroptosis
KEAP1/NRF2
dopaminergic neurons
older adults
normal aging
physical activity
neurodegenerative pathology aging
redox potential
ALS
wobbler mice
liver
hippocampus
cerebellum
glutamate cysteine ligase (GCL)
glutathione synthetase (GSS)
multidrug resistance protein (MRP)
gamma-glutamyl transpeptidase (GGT)
neuroprotection
Piper nigrum
H2O2-induced stress
anti-acetylcholine esterase activity
anti-glycation
green tea
EGCG
glaucoma
retinal ganglion cells
anti-oxidation
anti-inflammation
Alzheimer’s disease
dementia
sclerosis
schizophrenia
ataxia
therapy
brain cancers
NRF2
AHR
heme oxygenase
n/a
astrocytes
vascular endothelial cells
glutathione
nitric oxide
oxidants
disease progression
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
topic_facet vitamin C
ascorbic acid
subventricular zone
lateral ventricle extensions
adult neurogenesis
stroke
stem cell
mitochondria
oxidation
neuroinflammation
reactive oxygen species
age-related macular degeneration
D. tuberculatus
A2E
antioxidant
oxidative stress
inflammatory response
dopamine
Parkinson’s disease
neuromelanin
antioxidants
aminochrome
glutathione transferase M2-2
DT-diaphorase
ferroptosis
KEAP1/NRF2
dopaminergic neurons
older adults
normal aging
physical activity
neurodegenerative pathology aging
redox potential
ALS
wobbler mice
liver
hippocampus
cerebellum
glutamate cysteine ligase (GCL)
glutathione synthetase (GSS)
multidrug resistance protein (MRP)
gamma-glutamyl transpeptidase (GGT)
neuroprotection
Piper nigrum
H2O2-induced stress
anti-acetylcholine esterase activity
anti-glycation
green tea
EGCG
glaucoma
retinal ganglion cells
anti-oxidation
anti-inflammation
Alzheimer’s disease
dementia
sclerosis
schizophrenia
ataxia
therapy
brain cancers
NRF2
AHR
heme oxygenase
n/a
astrocytes
vascular endothelial cells
glutathione
nitric oxide
oxidants
disease progression
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
url ONIX_20250220_9783725822256_171