Emerging Strategies in Drug Development and Clinical Care in the Era of Personalized and Precision Medicine
In the dynamic realm of modern medicine, we stand at a pivotal juncture where the convergence of disease, drugs, and patient individuality is shaping a new paradigm. The field is transitioning from traditional drug development towards personalized therapeutic strategies tailored to the unique physio...
সংরক্ষণ করুন:
| বিন্যাস: | Online |
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| ভাষা: | ইংরেজি |
| প্রকাশিত: |
MDPI - Multidisciplinary Digital Publishing Institute
2025
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | ONIX_20250220_9783725822966_206 |
| ট্যাগগুলো: |
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| _version_ | 1869528968785297408 |
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| collection | Directory of Open Access Books |
| description | In the dynamic realm of modern medicine, we stand at a pivotal juncture where the convergence of disease, drugs, and patient individuality is shaping a new paradigm. The field is transitioning from traditional drug development towards personalized therapeutic strategies tailored to the unique physiology of each person. Over past decades, significant progress in preventive measures, diagnostic techniques, and treatment approaches has greatly improved patient care. However, the successful implementation of personalized medicine hinges on a thorough understanding of pathogenesis, therapeutic agents, biochemical mechanisms, drug interactions, and patient-specific factors.In this context, the objective of this reprint, "Emerging Strategies in Drug Development and Clinical Care in the Era of Personalized and Precision Medicine", is to provide a comprehensive collection of the latest research, showcasing the current state of knowledge and forecasting future trends in drug development and clinical practice. This reprint emphasizes the importance of understanding biochemical mechanisms of action, innovative drug formulations, and robust preclinical and clinical evaluations, including efficacy, pharmacokinetics, and toxicity, all within the framework of precision and personalized medicine. |
| format | Online |
| id | doab-20.500.12854ir-152842 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1528422025-02-20T13:09:37Z Emerging Strategies in Drug Development and Clinical Care in the Era of Personalized and Precision Medicine Dragoi, Cristina Manuela Nicolae, Alina Crenguța Dumitrescu, Ion-Bogdan muscle invasive bladder cancer exosomes biomarkers bladder cancer screening bladder cancer diagnosis spinal muscular atrophy compound motor action potential the children’s hospital of Philadelphia infant test of neuromuscular disorders hammersmith functional motor scale expanded bradykinin neuropathic pain chemotherapy allodynia CIPN Alzheimer’s disease antihypertensives amyloid tau angiotensin-converting enzyme inhibitor angiotensin II receptor blockers therapeutic strategies personalized medicine perampanel epilepsy population pharmacokinetics NONMEM therapeutic drug monitoring neurotensin subtype 1 receptor radiolabeled neurotensin targeted tumor imaging Tc-99m metabolic stability neprilysin angiotensin-converting enzyme peptidase-inhibition cardiovascular diseases DNA markers non-coding RNA selegiline anti-obesity adipogenesis lipogenesis lipolysis eWAT browning anamorelin metabolism molecular networking LC-MS/MS GHSR agonist chronic lymphocytic leukemia genetic alterations inhibitors of Bruton tyrosine kinase TP53 mutation immunoglobulin heavy chain variable region mutated model-informed precision dosing procalcitonin inflammation biomarker antibiotics critically ill pharmacodynamic target attainment precision medicine in silico clinical pharmacology computational tools patient-centered healthcare solid oral dosage form (SODF) medicine administration difficulty swallowing dysphagia medicine manipulation inpatient n/a thema EDItEUR::A The Arts::AT Performing arts::ATD Theatre studies thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology thema EDItEUR::A The Arts::AV Music In the dynamic realm of modern medicine, we stand at a pivotal juncture where the convergence of disease, drugs, and patient individuality is shaping a new paradigm. The field is transitioning from traditional drug development towards personalized therapeutic strategies tailored to the unique physiology of each person. Over past decades, significant progress in preventive measures, diagnostic techniques, and treatment approaches has greatly improved patient care. However, the successful implementation of personalized medicine hinges on a thorough understanding of pathogenesis, therapeutic agents, biochemical mechanisms, drug interactions, and patient-specific factors.In this context, the objective of this reprint, "Emerging Strategies in Drug Development and Clinical Care in the Era of Personalized and Precision Medicine", is to provide a comprehensive collection of the latest research, showcasing the current state of knowledge and forecasting future trends in drug development and clinical practice. This reprint emphasizes the importance of understanding biochemical mechanisms of action, innovative drug formulations, and robust preclinical and clinical evaluations, including efficacy, pharmacokinetics, and toxicity, all within the framework of precision and personalized medicine. 2025-02-20T13:09:34Z 2025-02-20T13:09:34Z 2024 book ONIX_20250220_9783725822966_206 9783725822966 9783725822959 https://directory.doabooks.org/handle/20.500.12854/152842 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/10075 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-2295-9 10.3390/books978-3-7258-2295-9 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725822966 9783725822959 258 Basel open access |
| spellingShingle | muscle invasive bladder cancer exosomes biomarkers bladder cancer screening bladder cancer diagnosis spinal muscular atrophy compound motor action potential the children’s hospital of Philadelphia infant test of neuromuscular disorders hammersmith functional motor scale expanded bradykinin neuropathic pain chemotherapy allodynia CIPN Alzheimer’s disease antihypertensives amyloid tau angiotensin-converting enzyme inhibitor angiotensin II receptor blockers therapeutic strategies personalized medicine perampanel epilepsy population pharmacokinetics NONMEM therapeutic drug monitoring neurotensin subtype 1 receptor radiolabeled neurotensin targeted tumor imaging Tc-99m metabolic stability neprilysin angiotensin-converting enzyme peptidase-inhibition cardiovascular diseases DNA markers non-coding RNA selegiline anti-obesity adipogenesis lipogenesis lipolysis eWAT browning anamorelin metabolism molecular networking LC-MS/MS GHSR agonist chronic lymphocytic leukemia genetic alterations inhibitors of Bruton tyrosine kinase TP53 mutation immunoglobulin heavy chain variable region mutated model-informed precision dosing procalcitonin inflammation biomarker antibiotics critically ill pharmacodynamic target attainment precision medicine in silico clinical pharmacology computational tools patient-centered healthcare solid oral dosage form (SODF) medicine administration difficulty swallowing dysphagia medicine manipulation inpatient n/a thema EDItEUR::A The Arts::AT Performing arts::ATD Theatre studies thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology thema EDItEUR::A The Arts::AV Music Emerging Strategies in Drug Development and Clinical Care in the Era of Personalized and Precision Medicine |
| title | Emerging Strategies in Drug Development and Clinical Care in the Era of Personalized and Precision Medicine |
| title_full | Emerging Strategies in Drug Development and Clinical Care in the Era of Personalized and Precision Medicine |
| title_fullStr | Emerging Strategies in Drug Development and Clinical Care in the Era of Personalized and Precision Medicine |
| title_full_unstemmed | Emerging Strategies in Drug Development and Clinical Care in the Era of Personalized and Precision Medicine |
| title_short | Emerging Strategies in Drug Development and Clinical Care in the Era of Personalized and Precision Medicine |
| title_sort | emerging strategies in drug development and clinical care in the era of personalized and precision medicine |
| topic | muscle invasive bladder cancer exosomes biomarkers bladder cancer screening bladder cancer diagnosis spinal muscular atrophy compound motor action potential the children’s hospital of Philadelphia infant test of neuromuscular disorders hammersmith functional motor scale expanded bradykinin neuropathic pain chemotherapy allodynia CIPN Alzheimer’s disease antihypertensives amyloid tau angiotensin-converting enzyme inhibitor angiotensin II receptor blockers therapeutic strategies personalized medicine perampanel epilepsy population pharmacokinetics NONMEM therapeutic drug monitoring neurotensin subtype 1 receptor radiolabeled neurotensin targeted tumor imaging Tc-99m metabolic stability neprilysin angiotensin-converting enzyme peptidase-inhibition cardiovascular diseases DNA markers non-coding RNA selegiline anti-obesity adipogenesis lipogenesis lipolysis eWAT browning anamorelin metabolism molecular networking LC-MS/MS GHSR agonist chronic lymphocytic leukemia genetic alterations inhibitors of Bruton tyrosine kinase TP53 mutation immunoglobulin heavy chain variable region mutated model-informed precision dosing procalcitonin inflammation biomarker antibiotics critically ill pharmacodynamic target attainment precision medicine in silico clinical pharmacology computational tools patient-centered healthcare solid oral dosage form (SODF) medicine administration difficulty swallowing dysphagia medicine manipulation inpatient n/a thema EDItEUR::A The Arts::AT Performing arts::ATD Theatre studies thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology thema EDItEUR::A The Arts::AV Music |
| topic_facet | muscle invasive bladder cancer exosomes biomarkers bladder cancer screening bladder cancer diagnosis spinal muscular atrophy compound motor action potential the children’s hospital of Philadelphia infant test of neuromuscular disorders hammersmith functional motor scale expanded bradykinin neuropathic pain chemotherapy allodynia CIPN Alzheimer’s disease antihypertensives amyloid tau angiotensin-converting enzyme inhibitor angiotensin II receptor blockers therapeutic strategies personalized medicine perampanel epilepsy population pharmacokinetics NONMEM therapeutic drug monitoring neurotensin subtype 1 receptor radiolabeled neurotensin targeted tumor imaging Tc-99m metabolic stability neprilysin angiotensin-converting enzyme peptidase-inhibition cardiovascular diseases DNA markers non-coding RNA selegiline anti-obesity adipogenesis lipogenesis lipolysis eWAT browning anamorelin metabolism molecular networking LC-MS/MS GHSR agonist chronic lymphocytic leukemia genetic alterations inhibitors of Bruton tyrosine kinase TP53 mutation immunoglobulin heavy chain variable region mutated model-informed precision dosing procalcitonin inflammation biomarker antibiotics critically ill pharmacodynamic target attainment precision medicine in silico clinical pharmacology computational tools patient-centered healthcare solid oral dosage form (SODF) medicine administration difficulty swallowing dysphagia medicine manipulation inpatient n/a thema EDItEUR::A The Arts::AT Performing arts::ATD Theatre studies thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology thema EDItEUR::A The Arts::AV Music |
| url | ONIX_20250220_9783725822966_206 |