Animal Models of Human Pathology

While animal models are essential for unraveling the biological mechanisms of human pathology, the growing depth of knowledge regarding these mechanisms—along with the intricate interplay of factors contributing to human diseases—demands ongoing characterization and refinement of existing models, as...

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Format: Online
Język:angielski
Wydane: MDPI - Multidisciplinary Digital Publishing Institute 2025
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Dostęp online:ONIX_20250220_9783725826919_392
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collection Directory of Open Access Books
description While animal models are essential for unraveling the biological mechanisms of human pathology, the growing depth of knowledge regarding these mechanisms—along with the intricate interplay of factors contributing to human diseases—demands ongoing characterization and refinement of existing models, as well as the development of improved disease models to better meet the needs of scientific inquiry. This reprint highlights a variety of animal disease models, exploring their features, mechanisms, usefulness, challenges, and limitations. It also includes research papers on refinements of existing models and the development of new disease models. The reprint offers insight into animal models of neurodegeneration, perinatal asphyxia, developmental hypertension, cisplatin toxicity, urinary bladder pain syndrome, autism spectrum disorders, cancer models, skin healing models, and models for testing cardioplegic solutions for cardiopulmonary bypass surgery.
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institution Directory of Open Access Books
language eng
publishDate 2025
publishDateRange 2025
publishDateSort 2025
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
record_format ojs
spelling doab-20.500.12854ir-1530282025-02-20T13:27:04Z Animal Models of Human Pathology Perše, Martina Animal models human diseases preclinical research reproducibility translatability thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MN Surgery While animal models are essential for unraveling the biological mechanisms of human pathology, the growing depth of knowledge regarding these mechanisms—along with the intricate interplay of factors contributing to human diseases—demands ongoing characterization and refinement of existing models, as well as the development of improved disease models to better meet the needs of scientific inquiry. This reprint highlights a variety of animal disease models, exploring their features, mechanisms, usefulness, challenges, and limitations. It also includes research papers on refinements of existing models and the development of new disease models. The reprint offers insight into animal models of neurodegeneration, perinatal asphyxia, developmental hypertension, cisplatin toxicity, urinary bladder pain syndrome, autism spectrum disorders, cancer models, skin healing models, and models for testing cardioplegic solutions for cardiopulmonary bypass surgery. 2025-02-20T13:27:01Z 2025-02-20T13:27:01Z 2024 book ONIX_20250220_9783725826919_392 9783725826919 9783725826926 https://directory.doabooks.org/handle/20.500.12854/153028 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/10284 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-2692-6 10.3390/books978-3-7258-2692-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725826919 9783725826926 440 Basel open access
spellingShingle Animal models
human diseases
preclinical research
reproducibility
translatability
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MN Surgery
Animal Models of Human Pathology
title Animal Models of Human Pathology
title_full Animal Models of Human Pathology
title_fullStr Animal Models of Human Pathology
title_full_unstemmed Animal Models of Human Pathology
title_short Animal Models of Human Pathology
title_sort animal models of human pathology
topic Animal models
human diseases
preclinical research
reproducibility
translatability
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MN Surgery
topic_facet Animal models
human diseases
preclinical research
reproducibility
translatability
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MN Surgery
url ONIX_20250220_9783725826919_392