Pharmacological Activities of Flavonoids and Its Analogues
Dear Colleagues, The development of new drugs continues to be an important point for global society. In recent years, there has been increased interest in the study of polyphenols due to the multiple pharmacological activities that they have demonstrated. Flavonoids are a class of polyphenols that h...
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MDPI - Multidisciplinary Digital Publishing Institute
2025
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| Online Access: | ONIX_20250220_9783725828241_450 |
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| description | Dear Colleagues, The development of new drugs continues to be an important point for global society. In recent years, there has been increased interest in the study of polyphenols due to the multiple pharmacological activities that they have demonstrated. Flavonoids are a class of polyphenols that have been widely studied; they are characterized as having a 15-carbon skeleton with a 2-phenylbenzopyranone core structure. They are classified as flavones, isoflavones, flavonols, anthocyanidins, flavanones, flavanols, chalcones, and aurones. Within the various classes, further differentiation is possible based on the number and nature of substituent groups attached to the rings; moreover, flavonoids can exist as free aglycones or conjugated glycosidic bonds. Flavonoids are present in almost all types of nourishment, and recent studies have focused on their biological, nutritional, pharmacological, and medicinal relevance. These kind of molecules, as well as their analogues, are of utmost relevance due to their multiple applications. Considering the above, we invite researchers to publish their findings on the pharmacological applications of flavonoids, as well as their analogs, while highlighting the importance of using these molecules as a basis for the development of new drugs. |
| format | Online |
| id | doab-20.500.12854ir-153086 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
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| spelling | doab-20.500.12854ir-1530862025-02-20T13:32:15Z Pharmacological Activities of Flavonoids and Its Analogues Calzada, Fernando Valdes, Miguel Usnea barbata (L.) Weber ex F.H. Wigg extracts phenolic secondary metabolites usnic acid polyphenols DPPH free-radical scavenging activity antibacterial activity flavonoids pinocembrin wound healing keratinocyte regenerative medicine quercetin coronavirus COVID-19 infection SARS-CoV-2 nanopreparations prevention treatment flavonoid lipophilicity MIC relationship bacteria cell membrane isoorientin gastric cancer cell apoptosis cell cycle cell migration reactive oxygen species Annona cherimolla Miller diabetes mellitus rutin oral antidiabetic drugs zinc oxide nanoparticles antimicrobial curcumin green synthesis drug discovery from natural products cyclophosphamide hesperidin apoptosis P53 iNOS oxidative stress Annona cherimola Miller antihyperglycemic activity in vivo assays in silico assays matrix metalloprotease (MMP) extracellular matrix (ECM) bone graft collagen natural product in vivo rabbit endothelial dysfunction NO bioavailability tangeretin cancer anti-cancer anti-proliferative anti-metastatic thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MN Surgery Dear Colleagues, The development of new drugs continues to be an important point for global society. In recent years, there has been increased interest in the study of polyphenols due to the multiple pharmacological activities that they have demonstrated. Flavonoids are a class of polyphenols that have been widely studied; they are characterized as having a 15-carbon skeleton with a 2-phenylbenzopyranone core structure. They are classified as flavones, isoflavones, flavonols, anthocyanidins, flavanones, flavanols, chalcones, and aurones. Within the various classes, further differentiation is possible based on the number and nature of substituent groups attached to the rings; moreover, flavonoids can exist as free aglycones or conjugated glycosidic bonds. Flavonoids are present in almost all types of nourishment, and recent studies have focused on their biological, nutritional, pharmacological, and medicinal relevance. These kind of molecules, as well as their analogues, are of utmost relevance due to their multiple applications. Considering the above, we invite researchers to publish their findings on the pharmacological applications of flavonoids, as well as their analogs, while highlighting the importance of using these molecules as a basis for the development of new drugs. 2025-02-20T13:32:12Z 2025-02-20T13:32:12Z 2024 book ONIX_20250220_9783725828241_450 9783725828241 9783725828234 https://directory.doabooks.org/handle/20.500.12854/153086 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/10292 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-2823-4 10.3390/books978-3-7258-2823-4 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725828241 9783725828234 228 Basel open access |
| spellingShingle | Usnea barbata (L.) Weber ex F.H. Wigg extracts phenolic secondary metabolites usnic acid polyphenols DPPH free-radical scavenging activity antibacterial activity flavonoids pinocembrin wound healing keratinocyte regenerative medicine quercetin coronavirus COVID-19 infection SARS-CoV-2 nanopreparations prevention treatment flavonoid lipophilicity MIC relationship bacteria cell membrane isoorientin gastric cancer cell apoptosis cell cycle cell migration reactive oxygen species Annona cherimolla Miller diabetes mellitus rutin oral antidiabetic drugs zinc oxide nanoparticles antimicrobial curcumin green synthesis drug discovery from natural products cyclophosphamide hesperidin apoptosis P53 iNOS oxidative stress Annona cherimola Miller antihyperglycemic activity in vivo assays in silico assays matrix metalloprotease (MMP) extracellular matrix (ECM) bone graft collagen natural product in vivo rabbit endothelial dysfunction NO bioavailability tangeretin cancer anti-cancer anti-proliferative anti-metastatic thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MN Surgery Pharmacological Activities of Flavonoids and Its Analogues |
| title | Pharmacological Activities of Flavonoids and Its Analogues |
| title_full | Pharmacological Activities of Flavonoids and Its Analogues |
| title_fullStr | Pharmacological Activities of Flavonoids and Its Analogues |
| title_full_unstemmed | Pharmacological Activities of Flavonoids and Its Analogues |
| title_short | Pharmacological Activities of Flavonoids and Its Analogues |
| title_sort | pharmacological activities of flavonoids and its analogues |
| topic | Usnea barbata (L.) Weber ex F.H. Wigg extracts phenolic secondary metabolites usnic acid polyphenols DPPH free-radical scavenging activity antibacterial activity flavonoids pinocembrin wound healing keratinocyte regenerative medicine quercetin coronavirus COVID-19 infection SARS-CoV-2 nanopreparations prevention treatment flavonoid lipophilicity MIC relationship bacteria cell membrane isoorientin gastric cancer cell apoptosis cell cycle cell migration reactive oxygen species Annona cherimolla Miller diabetes mellitus rutin oral antidiabetic drugs zinc oxide nanoparticles antimicrobial curcumin green synthesis drug discovery from natural products cyclophosphamide hesperidin apoptosis P53 iNOS oxidative stress Annona cherimola Miller antihyperglycemic activity in vivo assays in silico assays matrix metalloprotease (MMP) extracellular matrix (ECM) bone graft collagen natural product in vivo rabbit endothelial dysfunction NO bioavailability tangeretin cancer anti-cancer anti-proliferative anti-metastatic thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MN Surgery |
| topic_facet | Usnea barbata (L.) Weber ex F.H. Wigg extracts phenolic secondary metabolites usnic acid polyphenols DPPH free-radical scavenging activity antibacterial activity flavonoids pinocembrin wound healing keratinocyte regenerative medicine quercetin coronavirus COVID-19 infection SARS-CoV-2 nanopreparations prevention treatment flavonoid lipophilicity MIC relationship bacteria cell membrane isoorientin gastric cancer cell apoptosis cell cycle cell migration reactive oxygen species Annona cherimolla Miller diabetes mellitus rutin oral antidiabetic drugs zinc oxide nanoparticles antimicrobial curcumin green synthesis drug discovery from natural products cyclophosphamide hesperidin apoptosis P53 iNOS oxidative stress Annona cherimola Miller antihyperglycemic activity in vivo assays in silico assays matrix metalloprotease (MMP) extracellular matrix (ECM) bone graft collagen natural product in vivo rabbit endothelial dysfunction NO bioavailability tangeretin cancer anti-cancer anti-proliferative anti-metastatic thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MN Surgery |
| url | ONIX_20250220_9783725828241_450 |