Transcriptional Regulation in Bacteria
In the current post-genomic era, in which the full extent of the genes that are encoded on microbial genomes is known, the goal of research is to elucidate the entire transcriptional mechanism by which microorganisms express genes through transcriptional regulation with transcriptional regulatory fa...
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| Format: | Online |
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| Jezik: | engleski |
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MDPI - Multidisciplinary Digital Publishing Institute
2025
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| Online pristup: | ONIX_20250220_9783725829163_487 |
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| collection | Directory of Open Access Books |
| description | In the current post-genomic era, in which the full extent of the genes that are encoded on microbial genomes is known, the goal of research is to elucidate the entire transcriptional mechanism by which microorganisms express genes through transcriptional regulation with transcriptional regulatory factors. The genome sequence of microorganisms reveals their gene set and the set of transcriptional regulators that regulate the expression of those genes, providing a complete overview of the transcriptional regulatory mechanisms in microorganisms. Before genome sequencing was available, the analysis of the transcriptional regulation of transcriptional regulators occurred at the gene level, whereas it is now possible to analyze this at a genome-wide scale. To understand the intrinsic transcriptional regulatory mechanisms, it is necessary to understand that transcriptional regulation forms a hierarchical network structure, as well as the distinction between direct regulation and indirect effects.This Special Issue of Microorganisms, titled “Transcriptional Regulation in Bacteria”, includes ten original articles, providing new information about the transcriptional regulation of various functions in a wide variety of microorganisms. The analyses of transcriptional regulation revealed not only the molecular mechanisms of transcriptional regulation, but also the functional network of genes, leading to the elucidation of new biological functions of these microorganisms. |
| format | Online |
| id | doab-20.500.12854ir-153123 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1531232025-02-20T13:35:36Z Transcriptional Regulation in Bacteria Shimada, Tomohiro Yersinia pestis purR transcriptional regulation purine biosynthesis transcription factor glycogen ADP-glucose Escherichia coli gene regulation two-component system ethanol metabolism acetate metabolism Acinetobacter baumannii acetate: succinyl-CoA transferase (ASCT) Streptococcus mutans LiaSR two-component system chlorhexidine resistance efflux pump cells envelope stress responses transcriptional regulator PepR dipeptidase gene pepV resistant vancomycin resistance Bacillus thuringiensis Pseudomonas aeruginosa feather degradation comparative transcriptome analysis degradation mechanism σ factor acarbose Actinoplanes transcription regulation cell morphology osmotic stress response actinobacteria toxin–antitoxin Mycobacterium tuberculosis persistence arabinose operon genetic suppression transcription activation PBAD promoter epistasis bacterial adaptation two-component response systems silver resistance gene-by-environment interactions n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSV Zoology and animal sciences In the current post-genomic era, in which the full extent of the genes that are encoded on microbial genomes is known, the goal of research is to elucidate the entire transcriptional mechanism by which microorganisms express genes through transcriptional regulation with transcriptional regulatory factors. The genome sequence of microorganisms reveals their gene set and the set of transcriptional regulators that regulate the expression of those genes, providing a complete overview of the transcriptional regulatory mechanisms in microorganisms. Before genome sequencing was available, the analysis of the transcriptional regulation of transcriptional regulators occurred at the gene level, whereas it is now possible to analyze this at a genome-wide scale. To understand the intrinsic transcriptional regulatory mechanisms, it is necessary to understand that transcriptional regulation forms a hierarchical network structure, as well as the distinction between direct regulation and indirect effects.This Special Issue of Microorganisms, titled “Transcriptional Regulation in Bacteria”, includes ten original articles, providing new information about the transcriptional regulation of various functions in a wide variety of microorganisms. The analyses of transcriptional regulation revealed not only the molecular mechanisms of transcriptional regulation, but also the functional network of genes, leading to the elucidation of new biological functions of these microorganisms. 2025-02-20T13:35:34Z 2025-02-20T13:35:34Z 2024 book ONIX_20250220_9783725829163_487 9783725829163 9783725829156 https://directory.doabooks.org/handle/20.500.12854/153123 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/10323 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-2915-6 10.3390/books978-3-7258-2915-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725829163 9783725829156 180 Basel open access |
| spellingShingle | Yersinia pestis purR transcriptional regulation purine biosynthesis transcription factor glycogen ADP-glucose Escherichia coli gene regulation two-component system ethanol metabolism acetate metabolism Acinetobacter baumannii acetate: succinyl-CoA transferase (ASCT) Streptococcus mutans LiaSR two-component system chlorhexidine resistance efflux pump cells envelope stress responses transcriptional regulator PepR dipeptidase gene pepV resistant vancomycin resistance Bacillus thuringiensis Pseudomonas aeruginosa feather degradation comparative transcriptome analysis degradation mechanism σ factor acarbose Actinoplanes transcription regulation cell morphology osmotic stress response actinobacteria toxin–antitoxin Mycobacterium tuberculosis persistence arabinose operon genetic suppression transcription activation PBAD promoter epistasis bacterial adaptation two-component response systems silver resistance gene-by-environment interactions n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSV Zoology and animal sciences Transcriptional Regulation in Bacteria |
| title | Transcriptional Regulation in Bacteria |
| title_full | Transcriptional Regulation in Bacteria |
| title_fullStr | Transcriptional Regulation in Bacteria |
| title_full_unstemmed | Transcriptional Regulation in Bacteria |
| title_short | Transcriptional Regulation in Bacteria |
| title_sort | transcriptional regulation in bacteria |
| topic | Yersinia pestis purR transcriptional regulation purine biosynthesis transcription factor glycogen ADP-glucose Escherichia coli gene regulation two-component system ethanol metabolism acetate metabolism Acinetobacter baumannii acetate: succinyl-CoA transferase (ASCT) Streptococcus mutans LiaSR two-component system chlorhexidine resistance efflux pump cells envelope stress responses transcriptional regulator PepR dipeptidase gene pepV resistant vancomycin resistance Bacillus thuringiensis Pseudomonas aeruginosa feather degradation comparative transcriptome analysis degradation mechanism σ factor acarbose Actinoplanes transcription regulation cell morphology osmotic stress response actinobacteria toxin–antitoxin Mycobacterium tuberculosis persistence arabinose operon genetic suppression transcription activation PBAD promoter epistasis bacterial adaptation two-component response systems silver resistance gene-by-environment interactions n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSV Zoology and animal sciences |
| topic_facet | Yersinia pestis purR transcriptional regulation purine biosynthesis transcription factor glycogen ADP-glucose Escherichia coli gene regulation two-component system ethanol metabolism acetate metabolism Acinetobacter baumannii acetate: succinyl-CoA transferase (ASCT) Streptococcus mutans LiaSR two-component system chlorhexidine resistance efflux pump cells envelope stress responses transcriptional regulator PepR dipeptidase gene pepV resistant vancomycin resistance Bacillus thuringiensis Pseudomonas aeruginosa feather degradation comparative transcriptome analysis degradation mechanism σ factor acarbose Actinoplanes transcription regulation cell morphology osmotic stress response actinobacteria toxin–antitoxin Mycobacterium tuberculosis persistence arabinose operon genetic suppression transcription activation PBAD promoter epistasis bacterial adaptation two-component response systems silver resistance gene-by-environment interactions n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSV Zoology and animal sciences |
| url | ONIX_20250220_9783725829163_487 |