Brain Tumor Microenvironment
This Special Issue explores the brain tumor microenvironment, a complex interplay crucial for tumor behavior. We aim to achieve the following: characterize tumor microenvironment features; investigate cell–environment interactions; identify novel therapeutic targets; understand the role of extracell...
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| Format: | Online |
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| Idioma: | anglès |
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MDPI - Multidisciplinary Digital Publishing Institute
2025
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| Matèries: | |
| Accés en línia: | ONIX_20250220_9783725829248_491 |
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| collection | Directory of Open Access Books |
| description | This Special Issue explores the brain tumor microenvironment, a complex interplay crucial for tumor behavior. We aim to achieve the following: characterize tumor microenvironment features; investigate cell–environment interactions; identify novel therapeutic targets; understand the role of extracellular vesicles; develop and validate preclinical models; and integrate advanced imaging. Gliomas, like glioblastoma, pose significant challenges due to their aggressive nature and resistance to therapies. By understanding the microenvironment, we can develop more effective treatments, improve patient outcomes, and advance our understanding of tumor biology.This Special Issue is for neuroscientists, oncologists, radiologists, immunologists, pharmacologists, and researchers. This work builds upon research emphasizing the heterogeneity of the brain tumor microenvironment, the importance of patient-derived models, the role of extracellular vesicles in tumor progression, and the potential of artificial intelligence. By exploring these intricate interactions, we can unlock new avenues for therapeutic intervention and ultimately improve patient outcomes. |
| format | Online |
| id | doab-20.500.12854ir-153127 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1531272025-02-20T13:35:58Z Brain Tumor Microenvironment Mangiola, Annunziato Trevisi, Gianluca volume regulation transportome phlorizin brainstem glioma MR spectroscopy immunotherapy pediatric brain tumor vaccine therapy myo-inositol creatine choline brain tumor prediction healthcare deep convolutional features ensemble learning glioblastoma extracellular matrix cancer tumor microenvironment medulloblastoma extracellular vesicles exosomes MMP-2 EMMPRIN metastasis stem cell hypoxia niche autophagy therapy organoids slice culture tumormicroenvironment classification survival n/a glioma-associated microglia glioma-associated stromal cells immune infiltrate microenvironment peritumoral brain area peritumor tumor-infiltrating lymphocytes glioblastoma (GBM) heterogeneity tumour microenvironment (TME) myeloid cells microglia tumour associated macrophages (TAMs) therapeutic targeting thema EDItEUR::M Medicine and Nursing thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences This Special Issue explores the brain tumor microenvironment, a complex interplay crucial for tumor behavior. We aim to achieve the following: characterize tumor microenvironment features; investigate cell–environment interactions; identify novel therapeutic targets; understand the role of extracellular vesicles; develop and validate preclinical models; and integrate advanced imaging. Gliomas, like glioblastoma, pose significant challenges due to their aggressive nature and resistance to therapies. By understanding the microenvironment, we can develop more effective treatments, improve patient outcomes, and advance our understanding of tumor biology.This Special Issue is for neuroscientists, oncologists, radiologists, immunologists, pharmacologists, and researchers. This work builds upon research emphasizing the heterogeneity of the brain tumor microenvironment, the importance of patient-derived models, the role of extracellular vesicles in tumor progression, and the potential of artificial intelligence. By exploring these intricate interactions, we can unlock new avenues for therapeutic intervention and ultimately improve patient outcomes. 2025-02-20T13:35:56Z 2025-02-20T13:35:56Z 2025 book ONIX_20250220_9783725829248_491 9783725829248 9783725829231 https://directory.doabooks.org/handle/20.500.12854/153127 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/10451 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-2923-1 10.3390/books978-3-7258-2923-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725829248 9783725829231 194 Basel open access |
| spellingShingle | volume regulation transportome phlorizin brainstem glioma MR spectroscopy immunotherapy pediatric brain tumor vaccine therapy myo-inositol creatine choline brain tumor prediction healthcare deep convolutional features ensemble learning glioblastoma extracellular matrix cancer tumor microenvironment medulloblastoma extracellular vesicles exosomes MMP-2 EMMPRIN metastasis stem cell hypoxia niche autophagy therapy organoids slice culture tumormicroenvironment classification survival n/a glioma-associated microglia glioma-associated stromal cells immune infiltrate microenvironment peritumoral brain area peritumor tumor-infiltrating lymphocytes glioblastoma (GBM) heterogeneity tumour microenvironment (TME) myeloid cells microglia tumour associated macrophages (TAMs) therapeutic targeting thema EDItEUR::M Medicine and Nursing thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Brain Tumor Microenvironment |
| title | Brain Tumor Microenvironment |
| title_full | Brain Tumor Microenvironment |
| title_fullStr | Brain Tumor Microenvironment |
| title_full_unstemmed | Brain Tumor Microenvironment |
| title_short | Brain Tumor Microenvironment |
| title_sort | brain tumor microenvironment |
| topic | volume regulation transportome phlorizin brainstem glioma MR spectroscopy immunotherapy pediatric brain tumor vaccine therapy myo-inositol creatine choline brain tumor prediction healthcare deep convolutional features ensemble learning glioblastoma extracellular matrix cancer tumor microenvironment medulloblastoma extracellular vesicles exosomes MMP-2 EMMPRIN metastasis stem cell hypoxia niche autophagy therapy organoids slice culture tumormicroenvironment classification survival n/a glioma-associated microglia glioma-associated stromal cells immune infiltrate microenvironment peritumoral brain area peritumor tumor-infiltrating lymphocytes glioblastoma (GBM) heterogeneity tumour microenvironment (TME) myeloid cells microglia tumour associated macrophages (TAMs) therapeutic targeting thema EDItEUR::M Medicine and Nursing thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| topic_facet | volume regulation transportome phlorizin brainstem glioma MR spectroscopy immunotherapy pediatric brain tumor vaccine therapy myo-inositol creatine choline brain tumor prediction healthcare deep convolutional features ensemble learning glioblastoma extracellular matrix cancer tumor microenvironment medulloblastoma extracellular vesicles exosomes MMP-2 EMMPRIN metastasis stem cell hypoxia niche autophagy therapy organoids slice culture tumormicroenvironment classification survival n/a glioma-associated microglia glioma-associated stromal cells immune infiltrate microenvironment peritumoral brain area peritumor tumor-infiltrating lymphocytes glioblastoma (GBM) heterogeneity tumour microenvironment (TME) myeloid cells microglia tumour associated macrophages (TAMs) therapeutic targeting thema EDItEUR::M Medicine and Nursing thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| url | ONIX_20250220_9783725829248_491 |