Molecular and Cellular Mechanisms of Cancers
This reprint describes resistance to chemotherapy and radiotherapy, brain tumor stem cells, energy metabolism, epithelial-to-mesenchymal transition, immunotherapy, and reactive oxygen species phenotypes in glioblastoma.
Wedi'i Gadw mewn:
| Fformat: | Online |
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| Iaith: | Saesneg |
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MDPI - Multidisciplinary Digital Publishing Institute
2025
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| Pynciau: | |
| Mynediad Ar-lein: | ONIX_20250220_9783725829347_496 |
| Tagiau: |
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
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| _version_ | 1869530038069624832 |
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| collection | Directory of Open Access Books |
| description | This reprint describes resistance to chemotherapy and radiotherapy, brain tumor stem cells, energy metabolism, epithelial-to-mesenchymal transition, immunotherapy, and reactive oxygen species phenotypes in glioblastoma. |
| format | Online |
| id | doab-20.500.12854ir-153132 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1531322025-02-20T13:36:24Z Molecular and Cellular Mechanisms of Cancers Castresana, Javier S. Meléndez, Bárbara oxidative stress chaperone mediated autophagy (CMA) mitochondrial scavenger drug resistance reactive oxygen species (ROS), cell motility gliomas protein synthesis translation cap-dependent IRES astrocytoma glioblastoma serum proteins Protein Antibody Array decision tree survival glioblastoma stem cells (GSCs) epithelial-to-mesenchymal transition (EMT) markers GSC invasiveness transforming growth factor beta BzATP P2X7 receptor splice variants A and B tumor microenvironment exosomes microvesicles glioma stem cells immunotherapy resistance mechanisms programme death-1 immune checkpoint blockade glioblastoma (GBM) proteomics GBM cell-states recurrence tumour heterogeneity therapeutic targets WNK2 glioblastoma cell line autophagy inhibition autophagic flux glioma 5’-methylthioadenosine phosphorylase (MTAP) immunohistochemistry tumor biology proliferation migration invasion cancer stem cells M2 muscarinic receptors EGFR Notch cell cycle apoptosis radiotherapy membrane Hsp70 dose- and time-kinetics NK cell-based therapy non-coding RNA noncoding RNA BC200/miR-218-5p signaling circuit glioblastoma stem cells temozolomide resistance epithelial–mesenchymal transition (EMT) glioblastoma multiforme (GBM) 17β-estradiol (E2) estrogen receptors (ERs) adhesion arginine deprivation canavanine cancer cytoskeleton ER stress unfolded protein response IDH ADD3 high throughout techniques precision cerebral organoids nanomedicines astrocytes microglia lipocalin-2 inflammation glioblastomas hippo signaling pathway MST1/2 LATS1/2 YAP/TAZ TEADs energy metabolism glycolysis oxidative phosphorylation therapeutics gene expression profiling tumor model stem cell organoid heterogeneity immunosuppression microenvironment IDH1-mutation n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNS Epidemiology and Medical statistics This reprint describes resistance to chemotherapy and radiotherapy, brain tumor stem cells, energy metabolism, epithelial-to-mesenchymal transition, immunotherapy, and reactive oxygen species phenotypes in glioblastoma. 2025-02-20T13:36:22Z 2025-02-20T13:36:22Z 2024 book ONIX_20250220_9783725829347_496 9783725829347 9783725829330 https://directory.doabooks.org/handle/20.500.12854/153132 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/10385 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-2933-0 10.3390/books978-3-7258-2933-0 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725829347 9783725829330 400 Basel open access |
| spellingShingle | oxidative stress chaperone mediated autophagy (CMA) mitochondrial scavenger drug resistance reactive oxygen species (ROS), cell motility gliomas protein synthesis translation cap-dependent IRES astrocytoma glioblastoma serum proteins Protein Antibody Array decision tree survival glioblastoma stem cells (GSCs) epithelial-to-mesenchymal transition (EMT) markers GSC invasiveness transforming growth factor beta BzATP P2X7 receptor splice variants A and B tumor microenvironment exosomes microvesicles glioma stem cells immunotherapy resistance mechanisms programme death-1 immune checkpoint blockade glioblastoma (GBM) proteomics GBM cell-states recurrence tumour heterogeneity therapeutic targets WNK2 glioblastoma cell line autophagy inhibition autophagic flux glioma 5’-methylthioadenosine phosphorylase (MTAP) immunohistochemistry tumor biology proliferation migration invasion cancer stem cells M2 muscarinic receptors EGFR Notch cell cycle apoptosis radiotherapy membrane Hsp70 dose- and time-kinetics NK cell-based therapy non-coding RNA noncoding RNA BC200/miR-218-5p signaling circuit glioblastoma stem cells temozolomide resistance epithelial–mesenchymal transition (EMT) glioblastoma multiforme (GBM) 17β-estradiol (E2) estrogen receptors (ERs) adhesion arginine deprivation canavanine cancer cytoskeleton ER stress unfolded protein response IDH ADD3 high throughout techniques precision cerebral organoids nanomedicines astrocytes microglia lipocalin-2 inflammation glioblastomas hippo signaling pathway MST1/2 LATS1/2 YAP/TAZ TEADs energy metabolism glycolysis oxidative phosphorylation therapeutics gene expression profiling tumor model stem cell organoid heterogeneity immunosuppression microenvironment IDH1-mutation n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNS Epidemiology and Medical statistics Molecular and Cellular Mechanisms of Cancers |
| title | Molecular and Cellular Mechanisms of Cancers |
| title_full | Molecular and Cellular Mechanisms of Cancers |
| title_fullStr | Molecular and Cellular Mechanisms of Cancers |
| title_full_unstemmed | Molecular and Cellular Mechanisms of Cancers |
| title_short | Molecular and Cellular Mechanisms of Cancers |
| title_sort | molecular and cellular mechanisms of cancers |
| topic | oxidative stress chaperone mediated autophagy (CMA) mitochondrial scavenger drug resistance reactive oxygen species (ROS), cell motility gliomas protein synthesis translation cap-dependent IRES astrocytoma glioblastoma serum proteins Protein Antibody Array decision tree survival glioblastoma stem cells (GSCs) epithelial-to-mesenchymal transition (EMT) markers GSC invasiveness transforming growth factor beta BzATP P2X7 receptor splice variants A and B tumor microenvironment exosomes microvesicles glioma stem cells immunotherapy resistance mechanisms programme death-1 immune checkpoint blockade glioblastoma (GBM) proteomics GBM cell-states recurrence tumour heterogeneity therapeutic targets WNK2 glioblastoma cell line autophagy inhibition autophagic flux glioma 5’-methylthioadenosine phosphorylase (MTAP) immunohistochemistry tumor biology proliferation migration invasion cancer stem cells M2 muscarinic receptors EGFR Notch cell cycle apoptosis radiotherapy membrane Hsp70 dose- and time-kinetics NK cell-based therapy non-coding RNA noncoding RNA BC200/miR-218-5p signaling circuit glioblastoma stem cells temozolomide resistance epithelial–mesenchymal transition (EMT) glioblastoma multiforme (GBM) 17β-estradiol (E2) estrogen receptors (ERs) adhesion arginine deprivation canavanine cancer cytoskeleton ER stress unfolded protein response IDH ADD3 high throughout techniques precision cerebral organoids nanomedicines astrocytes microglia lipocalin-2 inflammation glioblastomas hippo signaling pathway MST1/2 LATS1/2 YAP/TAZ TEADs energy metabolism glycolysis oxidative phosphorylation therapeutics gene expression profiling tumor model stem cell organoid heterogeneity immunosuppression microenvironment IDH1-mutation n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNS Epidemiology and Medical statistics |
| topic_facet | oxidative stress chaperone mediated autophagy (CMA) mitochondrial scavenger drug resistance reactive oxygen species (ROS), cell motility gliomas protein synthesis translation cap-dependent IRES astrocytoma glioblastoma serum proteins Protein Antibody Array decision tree survival glioblastoma stem cells (GSCs) epithelial-to-mesenchymal transition (EMT) markers GSC invasiveness transforming growth factor beta BzATP P2X7 receptor splice variants A and B tumor microenvironment exosomes microvesicles glioma stem cells immunotherapy resistance mechanisms programme death-1 immune checkpoint blockade glioblastoma (GBM) proteomics GBM cell-states recurrence tumour heterogeneity therapeutic targets WNK2 glioblastoma cell line autophagy inhibition autophagic flux glioma 5’-methylthioadenosine phosphorylase (MTAP) immunohistochemistry tumor biology proliferation migration invasion cancer stem cells M2 muscarinic receptors EGFR Notch cell cycle apoptosis radiotherapy membrane Hsp70 dose- and time-kinetics NK cell-based therapy non-coding RNA noncoding RNA BC200/miR-218-5p signaling circuit glioblastoma stem cells temozolomide resistance epithelial–mesenchymal transition (EMT) glioblastoma multiforme (GBM) 17β-estradiol (E2) estrogen receptors (ERs) adhesion arginine deprivation canavanine cancer cytoskeleton ER stress unfolded protein response IDH ADD3 high throughout techniques precision cerebral organoids nanomedicines astrocytes microglia lipocalin-2 inflammation glioblastomas hippo signaling pathway MST1/2 LATS1/2 YAP/TAZ TEADs energy metabolism glycolysis oxidative phosphorylation therapeutics gene expression profiling tumor model stem cell organoid heterogeneity immunosuppression microenvironment IDH1-mutation n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNS Epidemiology and Medical statistics |
| url | ONIX_20250220_9783725829347_496 |