Scaffolds and Implants for Bone Regeneration

Bone defects caused by trauma, tumor, infection and a variety of congenital diseases are among the most common orthopedic disorders, and the clinical management of non-union bone defects is still a challenge for orthopedic surgeons. In recent years, bone implants based on metals, ceramics, and polym...

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Gepubliceerd in: MDPI - Multidisciplinary Digital Publishing Institute 2025
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collection Directory of Open Access Books
description Bone defects caused by trauma, tumor, infection and a variety of congenital diseases are among the most common orthopedic disorders, and the clinical management of non-union bone defects is still a challenge for orthopedic surgeons. In recent years, bone implants based on metals, ceramics, and polymers have been widely utilized and helped millions of patients. However, the rapid growth of the elderly demographic has tremendously intensified the occurrence of bone trauma cases, requiring once again the further development of effective strategies for bone reconstruction and regeneration. Therefore, the development of scaffolds and implants with new compositions, three-dimensional configurations, proper mechanical properties, and particular interactions with cells is highly expected. These new biomaterials may effectively promote bone regeneration and thus have a significant impact on individual patients and health care systems. In this Special Issue, we would like to present an innovative perspective on the scaffolds and implants for bone regeneration. Topics will include but not be limited to, the following: scaffold design and fabrication; biocompatibility and biodegradability; host response to implants; cell–scaffold interactions; and scaffold-based drug delivery. Both original research articles and reviews are very welcome.
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spelling doab-20.500.12854ir-1531402025-02-20T13:37:27Z Scaffolds and Implants for Bone Regeneration Zhang, Kunyu Feng, Qian Yu, Yongsheng Yang, Boguang maxillary sinus biomaterial sinus augmentation collagen membrane access window antrostomy osteotomy total hip arthroplasty protein adsorption proteomics osseointegration titanium bone regeneration biocompatibility host-implant response polycaprolactone biphasic calcium phosphate scaffold adipose stem cells nanocomposite Si3N4 cellular response degradability AMIC focal chondral lesions cartilage chondrogenesis collagen scaffolds biomaterials tissue engineering implants arthroplasty aseptic prosthetic loosening osteolysis particle-induced osteolysis mouse calvaria osteolysis model polyethylene particles wear particles titanium alloy electrodeposition ceramic coating indentation corrosion resistance cell proliferation human whole blood coagulation complement calcium phosphate zirconia femtosecond laser bone formation bone-bonding ability surface curvature trabecular bone histomorphometric parameters stiffness tensor geometric parameter deep learning convolution neural network thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBD Medical profession::MBDC Medical ethics and professional conduct Bone defects caused by trauma, tumor, infection and a variety of congenital diseases are among the most common orthopedic disorders, and the clinical management of non-union bone defects is still a challenge for orthopedic surgeons. In recent years, bone implants based on metals, ceramics, and polymers have been widely utilized and helped millions of patients. However, the rapid growth of the elderly demographic has tremendously intensified the occurrence of bone trauma cases, requiring once again the further development of effective strategies for bone reconstruction and regeneration. Therefore, the development of scaffolds and implants with new compositions, three-dimensional configurations, proper mechanical properties, and particular interactions with cells is highly expected. These new biomaterials may effectively promote bone regeneration and thus have a significant impact on individual patients and health care systems. In this Special Issue, we would like to present an innovative perspective on the scaffolds and implants for bone regeneration. Topics will include but not be limited to, the following: scaffold design and fabrication; biocompatibility and biodegradability; host response to implants; cell–scaffold interactions; and scaffold-based drug delivery. Both original research articles and reviews are very welcome. 2025-02-20T13:37:24Z 2025-02-20T13:37:24Z 2025 book ONIX_20250220_9783725829491_504 9783725829491 9783725829507 https://directory.doabooks.org/handle/20.500.12854/153140 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/10389 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-2950-7 10.3390/books978-3-7258-2950-7 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725829491 9783725829507 184 Basel open access
spellingShingle maxillary sinus
biomaterial
sinus augmentation
collagen membrane
access window
antrostomy
osteotomy
total hip arthroplasty
protein adsorption
proteomics
osseointegration
titanium
bone regeneration
biocompatibility
host-implant response
polycaprolactone
biphasic calcium phosphate
scaffold
adipose
stem cells
nanocomposite
Si3N4
cellular response
degradability
AMIC
focal chondral lesions
cartilage chondrogenesis
collagen scaffolds
biomaterials
tissue engineering
implants
arthroplasty
aseptic prosthetic loosening
osteolysis
particle-induced osteolysis
mouse calvaria osteolysis model
polyethylene particles
wear particles
titanium alloy
electrodeposition
ceramic coating
indentation
corrosion resistance
cell proliferation
human whole blood
coagulation
complement
calcium phosphate
zirconia
femtosecond laser
bone formation
bone-bonding ability
surface curvature
trabecular bone
histomorphometric parameters
stiffness tensor
geometric parameter
deep learning
convolution neural network
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBD Medical profession::MBDC Medical ethics and professional conduct
Scaffolds and Implants for Bone Regeneration
title Scaffolds and Implants for Bone Regeneration
title_full Scaffolds and Implants for Bone Regeneration
title_fullStr Scaffolds and Implants for Bone Regeneration
title_full_unstemmed Scaffolds and Implants for Bone Regeneration
title_short Scaffolds and Implants for Bone Regeneration
title_sort scaffolds and implants for bone regeneration
topic maxillary sinus
biomaterial
sinus augmentation
collagen membrane
access window
antrostomy
osteotomy
total hip arthroplasty
protein adsorption
proteomics
osseointegration
titanium
bone regeneration
biocompatibility
host-implant response
polycaprolactone
biphasic calcium phosphate
scaffold
adipose
stem cells
nanocomposite
Si3N4
cellular response
degradability
AMIC
focal chondral lesions
cartilage chondrogenesis
collagen scaffolds
biomaterials
tissue engineering
implants
arthroplasty
aseptic prosthetic loosening
osteolysis
particle-induced osteolysis
mouse calvaria osteolysis model
polyethylene particles
wear particles
titanium alloy
electrodeposition
ceramic coating
indentation
corrosion resistance
cell proliferation
human whole blood
coagulation
complement
calcium phosphate
zirconia
femtosecond laser
bone formation
bone-bonding ability
surface curvature
trabecular bone
histomorphometric parameters
stiffness tensor
geometric parameter
deep learning
convolution neural network
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBD Medical profession::MBDC Medical ethics and professional conduct
topic_facet maxillary sinus
biomaterial
sinus augmentation
collagen membrane
access window
antrostomy
osteotomy
total hip arthroplasty
protein adsorption
proteomics
osseointegration
titanium
bone regeneration
biocompatibility
host-implant response
polycaprolactone
biphasic calcium phosphate
scaffold
adipose
stem cells
nanocomposite
Si3N4
cellular response
degradability
AMIC
focal chondral lesions
cartilage chondrogenesis
collagen scaffolds
biomaterials
tissue engineering
implants
arthroplasty
aseptic prosthetic loosening
osteolysis
particle-induced osteolysis
mouse calvaria osteolysis model
polyethylene particles
wear particles
titanium alloy
electrodeposition
ceramic coating
indentation
corrosion resistance
cell proliferation
human whole blood
coagulation
complement
calcium phosphate
zirconia
femtosecond laser
bone formation
bone-bonding ability
surface curvature
trabecular bone
histomorphometric parameters
stiffness tensor
geometric parameter
deep learning
convolution neural network
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBD Medical profession::MBDC Medical ethics and professional conduct
url ONIX_20250220_9783725829491_504