A Commemorative Issue in Honor of Professor Merlin G. Butler's Retirement

This Special Issue of the International Journal of Molecular Sciences is dedicated to Professor Merlin G. Butler, in recognition of his retirement and to commemorate his substantial contributions to the field of genetics and genomics-driven medical care. Dr. Butler has been a pioneer in the expansio...

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collection Directory of Open Access Books
description This Special Issue of the International Journal of Molecular Sciences is dedicated to Professor Merlin G. Butler, in recognition of his retirement and to commemorate his substantial contributions to the field of genetics and genomics-driven medical care. Dr. Butler has been a pioneer in the expansion of our understanding of how genetics can help inform healthcare professionals regarding individuals with neurodevelopmental syndromes and conditions. This commemorative Special Issue focuses on original research and review articles evaluating innovative molecular and computational approaches for studying the mechanisms underlying the expression and development of both common and rare genetic conditions.
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publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-1531612025-02-20T13:39:28Z A Commemorative Issue in Honor of Professor Merlin G. Butler's Retirement Godler, David E. Veatch, Olivia J. DNA methylation episignature epigenetics copy number variant neurodevelopmental disorder genomic disorder FMR1 gene fragile X syndrome FMR1 gray zone or intermediate alleles connective tissue-related disorders sleep-related breathing disorders obstructive sleep apnea polysomnography growth hormone before-after comparison obesity genetics monogenic polygenic Prader-Willi syndrome Prader-Willi syndrome genotype phenotype hypothalamus brain development array CGH CGR complex genomic rearrangements chromothripsis cryptic rearrangement OGM optical genome mapping genome sequencing DEE developmental and epileptic encephalopathy SCN1A SCN2A body composition muscle strength non-alcoholic fatty liver disease children Prader-Willi syndrome (PWS) high-resolution chromosomal microarray PWS molecular genetic classes typical 15q11-q13 deletion subtypes maternal disomy 15 subclasses atypical PWS genetic findings DESTINY PWS Prader–Willi syndrome hyperphagia clinical trials Prader–Willi syndrome (PWS) typical 15q11-q13 Type I Type II deletions 15q11.2 BP1-BP2 deletion clinical findings autonomic nervous system (ANS) childhood obesity FMR1 epigenetic boundary premutation methylation intellectual disability n/a Mowat–Wilson syndrome (MWS) case report review ZEB2 gene variants ZEB2 protein domains and defects ZEB2 functional molecular interactions thema EDItEUR::M Medicine and Nursing This Special Issue of the International Journal of Molecular Sciences is dedicated to Professor Merlin G. Butler, in recognition of his retirement and to commemorate his substantial contributions to the field of genetics and genomics-driven medical care. Dr. Butler has been a pioneer in the expansion of our understanding of how genetics can help inform healthcare professionals regarding individuals with neurodevelopmental syndromes and conditions. This commemorative Special Issue focuses on original research and review articles evaluating innovative molecular and computational approaches for studying the mechanisms underlying the expression and development of both common and rare genetic conditions. 2025-02-20T13:39:25Z 2025-02-20T13:39:25Z 2025 book ONIX_20250220_9783725830329_525 9783725830329 9783725830312 https://directory.doabooks.org/handle/20.500.12854/153161 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/10424 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-3031-2 10.3390/books978-3-7258-3031-2 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725830329 9783725830312 200 Basel open access
spellingShingle DNA methylation
episignature
epigenetics
copy number variant
neurodevelopmental disorder
genomic disorder
FMR1 gene
fragile X syndrome
FMR1 gray zone or intermediate alleles
connective tissue-related disorders
sleep-related breathing disorders
obstructive sleep apnea
polysomnography
growth hormone
before-after comparison
obesity
genetics
monogenic
polygenic
Prader-Willi
syndrome
Prader-Willi syndrome
genotype
phenotype
hypothalamus
brain development
array CGH
CGR
complex genomic rearrangements
chromothripsis
cryptic rearrangement
OGM
optical genome mapping
genome sequencing
DEE
developmental and epileptic encephalopathy
SCN1A
SCN2A
body composition
muscle strength
non-alcoholic fatty liver disease
children
Prader-Willi syndrome (PWS)
high-resolution chromosomal microarray
PWS molecular genetic classes
typical 15q11-q13 deletion subtypes
maternal disomy 15 subclasses
atypical PWS genetic findings
DESTINY PWS
Prader–Willi syndrome
hyperphagia
clinical trials
Prader–Willi syndrome (PWS)
typical 15q11-q13 Type I
Type II deletions
15q11.2 BP1-BP2 deletion
clinical findings
autonomic nervous system (ANS)
childhood obesity
FMR1
epigenetic boundary
premutation
methylation intellectual disability
n/a
Mowat–Wilson syndrome (MWS)
case report
review
ZEB2 gene variants
ZEB2 protein domains and defects
ZEB2 functional molecular interactions
thema EDItEUR::M Medicine and Nursing
A Commemorative Issue in Honor of Professor Merlin G. Butler's Retirement
title A Commemorative Issue in Honor of Professor Merlin G. Butler's Retirement
title_full A Commemorative Issue in Honor of Professor Merlin G. Butler's Retirement
title_fullStr A Commemorative Issue in Honor of Professor Merlin G. Butler's Retirement
title_full_unstemmed A Commemorative Issue in Honor of Professor Merlin G. Butler's Retirement
title_short A Commemorative Issue in Honor of Professor Merlin G. Butler's Retirement
title_sort commemorative issue in honor of professor merlin g butler s retirement
topic DNA methylation
episignature
epigenetics
copy number variant
neurodevelopmental disorder
genomic disorder
FMR1 gene
fragile X syndrome
FMR1 gray zone or intermediate alleles
connective tissue-related disorders
sleep-related breathing disorders
obstructive sleep apnea
polysomnography
growth hormone
before-after comparison
obesity
genetics
monogenic
polygenic
Prader-Willi
syndrome
Prader-Willi syndrome
genotype
phenotype
hypothalamus
brain development
array CGH
CGR
complex genomic rearrangements
chromothripsis
cryptic rearrangement
OGM
optical genome mapping
genome sequencing
DEE
developmental and epileptic encephalopathy
SCN1A
SCN2A
body composition
muscle strength
non-alcoholic fatty liver disease
children
Prader-Willi syndrome (PWS)
high-resolution chromosomal microarray
PWS molecular genetic classes
typical 15q11-q13 deletion subtypes
maternal disomy 15 subclasses
atypical PWS genetic findings
DESTINY PWS
Prader–Willi syndrome
hyperphagia
clinical trials
Prader–Willi syndrome (PWS)
typical 15q11-q13 Type I
Type II deletions
15q11.2 BP1-BP2 deletion
clinical findings
autonomic nervous system (ANS)
childhood obesity
FMR1
epigenetic boundary
premutation
methylation intellectual disability
n/a
Mowat–Wilson syndrome (MWS)
case report
review
ZEB2 gene variants
ZEB2 protein domains and defects
ZEB2 functional molecular interactions
thema EDItEUR::M Medicine and Nursing
topic_facet DNA methylation
episignature
epigenetics
copy number variant
neurodevelopmental disorder
genomic disorder
FMR1 gene
fragile X syndrome
FMR1 gray zone or intermediate alleles
connective tissue-related disorders
sleep-related breathing disorders
obstructive sleep apnea
polysomnography
growth hormone
before-after comparison
obesity
genetics
monogenic
polygenic
Prader-Willi
syndrome
Prader-Willi syndrome
genotype
phenotype
hypothalamus
brain development
array CGH
CGR
complex genomic rearrangements
chromothripsis
cryptic rearrangement
OGM
optical genome mapping
genome sequencing
DEE
developmental and epileptic encephalopathy
SCN1A
SCN2A
body composition
muscle strength
non-alcoholic fatty liver disease
children
Prader-Willi syndrome (PWS)
high-resolution chromosomal microarray
PWS molecular genetic classes
typical 15q11-q13 deletion subtypes
maternal disomy 15 subclasses
atypical PWS genetic findings
DESTINY PWS
Prader–Willi syndrome
hyperphagia
clinical trials
Prader–Willi syndrome (PWS)
typical 15q11-q13 Type I
Type II deletions
15q11.2 BP1-BP2 deletion
clinical findings
autonomic nervous system (ANS)
childhood obesity
FMR1
epigenetic boundary
premutation
methylation intellectual disability
n/a
Mowat–Wilson syndrome (MWS)
case report
review
ZEB2 gene variants
ZEB2 protein domains and defects
ZEB2 functional molecular interactions
thema EDItEUR::M Medicine and Nursing
url ONIX_20250220_9783725830329_525