Renin-Angiotensin System in Cardiovascular Biology

The renin–angiotensin system (RAS) plays an important role in maintaining the salt and water balance of very diverse animal species under very diverse conditions. Angiotensin II (Ang II) is a hormone with much more complex actions than is typical for other agonists with heterotrimeric G protein-coup...

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Publicado em: MDPI - Multidisciplinary Digital Publishing Institute 2025
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collection Directory of Open Access Books
description The renin–angiotensin system (RAS) plays an important role in maintaining the salt and water balance of very diverse animal species under very diverse conditions. Angiotensin II (Ang II) is a hormone with much more complex actions than is typical for other agonists with heterotrimeric G protein-coupled receptors (GPCRs). Its principal receptor, angiotensin type 1 receptor (AT1R), is distributed in many cells of the body in diverse organs, controlling the water and salt balance, vascular contractility, and blood pressure. This Special Issue provides original research papers and review articles regarding the latest insights into the complexity of the cell signaling and biological mechanisms of the RAS components to propose novel mechanisms in cardiovascular physiology and pathophysiology. By targeting this system, works may provide novel therapeutic potential regarding cardiovascular and related diseases such as hypertension, heart failure, atherosclerosis, and diabetes mellitus.
format Online
id doab-20.500.12854ir-153173
institution Directory of Open Access Books
language eng
publishDate 2025
publishDateRange 2025
publishDateSort 2025
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
record_format ojs
spelling doab-20.500.12854ir-1531732025-02-20T13:40:36Z Renin-Angiotensin System in Cardiovascular Biology Szekeres, Mária Nádasy, György L. Balla, András renin-angiotensin system renin-angiotensin-aldosterone system angiotensin II angiotensin receptors AT1R AT2R angiotensin converting enzyme ACE ACE2 ACEI signal transduction cardiovascular system hypertension atherosclerosis heart failure Long COVID endothelial cell reactive oxygen species G protein-coupled receptors GPCR thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBP Health systems and services::MBPK Mental health services The renin–angiotensin system (RAS) plays an important role in maintaining the salt and water balance of very diverse animal species under very diverse conditions. Angiotensin II (Ang II) is a hormone with much more complex actions than is typical for other agonists with heterotrimeric G protein-coupled receptors (GPCRs). Its principal receptor, angiotensin type 1 receptor (AT1R), is distributed in many cells of the body in diverse organs, controlling the water and salt balance, vascular contractility, and blood pressure. This Special Issue provides original research papers and review articles regarding the latest insights into the complexity of the cell signaling and biological mechanisms of the RAS components to propose novel mechanisms in cardiovascular physiology and pathophysiology. By targeting this system, works may provide novel therapeutic potential regarding cardiovascular and related diseases such as hypertension, heart failure, atherosclerosis, and diabetes mellitus. 2025-02-20T13:40:33Z 2025-02-20T13:40:33Z 2025 book ONIX_20250220_9783725831098_537 9783725831098 9783725831104 https://directory.doabooks.org/handle/20.500.12854/153173 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/10449 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-3110-4 10.3390/books978-3-7258-3110-4 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725831098 9783725831104 170 Basel open access
spellingShingle renin-angiotensin system
renin-angiotensin-aldosterone system
angiotensin II
angiotensin receptors
AT1R
AT2R
angiotensin converting enzyme
ACE
ACE2
ACEI
signal transduction
cardiovascular system
hypertension
atherosclerosis
heart failure
Long COVID
endothelial cell
reactive oxygen species
G protein-coupled receptors
GPCR
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBP Health systems and services::MBPK Mental health services
Renin-Angiotensin System in Cardiovascular Biology
title Renin-Angiotensin System in Cardiovascular Biology
title_full Renin-Angiotensin System in Cardiovascular Biology
title_fullStr Renin-Angiotensin System in Cardiovascular Biology
title_full_unstemmed Renin-Angiotensin System in Cardiovascular Biology
title_short Renin-Angiotensin System in Cardiovascular Biology
title_sort renin angiotensin system in cardiovascular biology
topic renin-angiotensin system
renin-angiotensin-aldosterone system
angiotensin II
angiotensin receptors
AT1R
AT2R
angiotensin converting enzyme
ACE
ACE2
ACEI
signal transduction
cardiovascular system
hypertension
atherosclerosis
heart failure
Long COVID
endothelial cell
reactive oxygen species
G protein-coupled receptors
GPCR
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBP Health systems and services::MBPK Mental health services
topic_facet renin-angiotensin system
renin-angiotensin-aldosterone system
angiotensin II
angiotensin receptors
AT1R
AT2R
angiotensin converting enzyme
ACE
ACE2
ACEI
signal transduction
cardiovascular system
hypertension
atherosclerosis
heart failure
Long COVID
endothelial cell
reactive oxygen species
G protein-coupled receptors
GPCR
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBP Health systems and services::MBPK Mental health services
url ONIX_20250220_9783725831098_537