Rat Lungworm Disease
The pathogenic nematode Angiostrongylus cantonensis is a leading global causative agent of eosinophilic meningitis in humans and other species. Clinically, this disease is known as neuroangiostrongyliasis but is colloquially recognized as rat lungworm disease. This disease has resulted in morbidity...
שמור ב:
| פורמט: | Online |
|---|---|
| שפה: | אנגלית |
| יצא לאור: |
MDPI - Multidisciplinary Digital Publishing Institute
2025
|
| נושאים: | |
| גישה מקוונת: | ONIX_20250812T095121_9783725832989_111 |
| תגים: |
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|
| _version_ | 1869524313148751872 |
|---|---|
| collection | Directory of Open Access Books |
| description | The pathogenic nematode Angiostrongylus cantonensis is a leading global causative agent of eosinophilic meningitis in humans and other species. Clinically, this disease is known as neuroangiostrongyliasis but is colloquially recognized as rat lungworm disease. This disease has resulted in morbidity and mortality in humans and other accidental hosts, and the geographic range of this pathogen continues to increase through global expansion. The first five studies in this reprint provide updates on recent global research efforts and distribution, including studies from India, Brazil, Ecuador, reports of coinfections in Spain, and the genetic-based determination of global spread patterns of A. cantonensis. The other six studies evaluate potential mechanisms for prevention, such as creating barriers to decrease the mollusk infestation of crops; disease diagnostics applying both DNA and antibody-based methods; and current approaches to the pharmacological management of this disease using a multi-drug approach in humans, as well as investigating the effects on A. cantonensis of a commercially available antiparasitic currently used for controlling heartworm, fleas, and ticks in dogs. Guest Editor Susan I. Jarvi is a Professor in the department of Pharmaceutical Sciences, where she teaches Pharmaceutical Immunology and other infectious disease-related subjects at the Daniel K. Inouye College of Pharmacy at the University of Hawaii in Hilo, HI. |
| format | Online |
| id | doab-20.500.12854ir-165162 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1651622025-08-12T08:07:44Z Rat Lungworm Disease Jarvi, Susan rat lungworm neuroangiostrongyliasis treatment anthelmintics albendazole pyrantel pamoate Angiostrongylus cantonensis moxidectin Simparica angiostrongyliasis rat lungworm disease eosinophilic meningitis serological detection ELISA 31 kDa lateral flow assay immunochromatographic test antigen detection 31-kDa antigen active angiostrongyliasis Angiostrongylus mackerrasae Angiostrongylus malaysiensis mitochondrial gene distribution phylogeny Angiostrongyliasis Parmarion martensi valve effect barrier deterministic model crops human angiostrongyliasis Indian subcontinent Invasive species eosinophilic meningoencephalitis cytochrome c oxidase subunit I Rattus norvegicus Rattus rattus parasite fauna coinfections Achatina fulica slugs snails zoonotic helminths Aelurostrongylus abstrusus thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNS Epidemiology and Medical statistics The pathogenic nematode Angiostrongylus cantonensis is a leading global causative agent of eosinophilic meningitis in humans and other species. Clinically, this disease is known as neuroangiostrongyliasis but is colloquially recognized as rat lungworm disease. This disease has resulted in morbidity and mortality in humans and other accidental hosts, and the geographic range of this pathogen continues to increase through global expansion. The first five studies in this reprint provide updates on recent global research efforts and distribution, including studies from India, Brazil, Ecuador, reports of coinfections in Spain, and the genetic-based determination of global spread patterns of A. cantonensis. The other six studies evaluate potential mechanisms for prevention, such as creating barriers to decrease the mollusk infestation of crops; disease diagnostics applying both DNA and antibody-based methods; and current approaches to the pharmacological management of this disease using a multi-drug approach in humans, as well as investigating the effects on A. cantonensis of a commercially available antiparasitic currently used for controlling heartworm, fleas, and ticks in dogs. Guest Editor Susan I. Jarvi is a Professor in the department of Pharmaceutical Sciences, where she teaches Pharmaceutical Immunology and other infectious disease-related subjects at the Daniel K. Inouye College of Pharmacy at the University of Hawaii in Hilo, HI. 2025-08-12T08:07:41Z 2025-08-12T08:07:41Z 2025 book ONIX_20250812T095121_9783725832989_111 9783725832989 9783725832972 https://directory.doabooks.org/handle/20.500.12854/165162 eng image/jpeg Attribution 4.0 International https://mdpi.com/books https://mdpi.com/books/pdfview/book/10560 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-3297-2 10.3390/books978-3-7258-3297-2 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725832989 9783725832972 148 open access |
| spellingShingle | rat lungworm neuroangiostrongyliasis treatment anthelmintics albendazole pyrantel pamoate Angiostrongylus cantonensis moxidectin Simparica angiostrongyliasis rat lungworm disease eosinophilic meningitis serological detection ELISA 31 kDa lateral flow assay immunochromatographic test antigen detection 31-kDa antigen active angiostrongyliasis Angiostrongylus mackerrasae Angiostrongylus malaysiensis mitochondrial gene distribution phylogeny Angiostrongyliasis Parmarion martensi valve effect barrier deterministic model crops human angiostrongyliasis Indian subcontinent Invasive species eosinophilic meningoencephalitis cytochrome c oxidase subunit I Rattus norvegicus Rattus rattus parasite fauna coinfections Achatina fulica slugs snails zoonotic helminths Aelurostrongylus abstrusus thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNS Epidemiology and Medical statistics Rat Lungworm Disease |
| title | Rat Lungworm Disease |
| title_full | Rat Lungworm Disease |
| title_fullStr | Rat Lungworm Disease |
| title_full_unstemmed | Rat Lungworm Disease |
| title_short | Rat Lungworm Disease |
| title_sort | rat lungworm disease |
| topic | rat lungworm neuroangiostrongyliasis treatment anthelmintics albendazole pyrantel pamoate Angiostrongylus cantonensis moxidectin Simparica angiostrongyliasis rat lungworm disease eosinophilic meningitis serological detection ELISA 31 kDa lateral flow assay immunochromatographic test antigen detection 31-kDa antigen active angiostrongyliasis Angiostrongylus mackerrasae Angiostrongylus malaysiensis mitochondrial gene distribution phylogeny Angiostrongyliasis Parmarion martensi valve effect barrier deterministic model crops human angiostrongyliasis Indian subcontinent Invasive species eosinophilic meningoencephalitis cytochrome c oxidase subunit I Rattus norvegicus Rattus rattus parasite fauna coinfections Achatina fulica slugs snails zoonotic helminths Aelurostrongylus abstrusus thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNS Epidemiology and Medical statistics |
| topic_facet | rat lungworm neuroangiostrongyliasis treatment anthelmintics albendazole pyrantel pamoate Angiostrongylus cantonensis moxidectin Simparica angiostrongyliasis rat lungworm disease eosinophilic meningitis serological detection ELISA 31 kDa lateral flow assay immunochromatographic test antigen detection 31-kDa antigen active angiostrongyliasis Angiostrongylus mackerrasae Angiostrongylus malaysiensis mitochondrial gene distribution phylogeny Angiostrongyliasis Parmarion martensi valve effect barrier deterministic model crops human angiostrongyliasis Indian subcontinent Invasive species eosinophilic meningoencephalitis cytochrome c oxidase subunit I Rattus norvegicus Rattus rattus parasite fauna coinfections Achatina fulica slugs snails zoonotic helminths Aelurostrongylus abstrusus thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNS Epidemiology and Medical statistics |
| url | ONIX_20250812T095121_9783725832989_111 |