Development, Characterization, and Application of Bioactive Peptides, Diagnostic Biomarkers, and Pharmaceutical Proteins
As proteins and peptides are the most abundant and versatile biomolecules, playing many critical roles in nearly every life process, many proteins/peptides are also strongly associated with human health and diseases. Various protein/peptide molecules have been proposed as biomarkers with potential d...
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| Формат: | Online |
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| Мова: | Англійська |
| Опубліковано: |
MDPI - Multidisciplinary Digital Publishing Institute
2025
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| Предмети: | |
| Онлайн доступ: | ONIX_20250812T110751_9783725835645_73 |
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| _version_ | 1869516630801776640 |
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| collection | Directory of Open Access Books |
| description | As proteins and peptides are the most abundant and versatile biomolecules, playing many critical roles in nearly every life process, many proteins/peptides are also strongly associated with human health and diseases. Various protein/peptide molecules have been proposed as biomarkers with potential diagnostic or prognostic value, and renewed interests in exploring peptides/proteins as crucial targets for therapeutic purposes have arisen. Bioactive proteins/peptides including various enzymes, antibodies, and peptide hormones have been developed and serve as biopharmaceuticals for clinical use. In addition, the advances in protein/peptide technology include the development of pharmaceutical molecular platforms such as peptide nanoparticles and drug delivery systems. This Special Issue aimed to present research articles that address the topic of biopharmaceutical proteins/peptides. Studies that contribute to advancing the molecular engineering and production process of biopharmaceutical peptides/proteins, as well as papers providing novel application-oriented perspectives, were also included. |
| format | Online |
| id | doab-20.500.12854ir-165317 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1653172025-08-12T09:20:31Z Development, Characterization, and Application of Bioactive Peptides, Diagnostic Biomarkers, and Pharmaceutical Proteins Won, Hyung-Sik Kim, Ji-Hun glioma radiation proteomic valproic acid HDAC inhibitor collagen-derived peptide Prolyl-hydroxyproline muscle atrophy mouse C2C12 skeletal myotubes ubiquitin ligases Aedes aegypti adipokinetic hormone corazonin hormone molecular modelling yellow fever mosquito peptide signalling antimicrobial peptides host defense peptides LL37 structure biophysical human antimicrobial peptides photodynamic therapy anticancer therapy bioconjugate peptide derivatives nanoparticle bioactive peptides genetic engineering heterologous expression high-throughput screening RiPPs synthetic biology peptide synthesis antimicrobial cyclic peptide murepavadin acylation agents solid phase antibiotic antibacterial activity prothrombin activator RAPClot™ prototype tube ?-radiation enzymatic activity blood clotting serum biochemical analytes antimicrobial peptide rattusin antibiotics DNA binding cytotoxicity melittin 6-aminohexanoic acid leucine drug-resistant bacteria 1,2,4-triazoles antifungal peptides synthesis dipeptides fluconazole non-protein amino acids Aspergillus candidus Aspergillus versicolor Aspergillus flavus Alternaria alternate Ulocladium botrytis Aureobasidium pullulans peptidylglycine alpha-amidating monooxygenase C-terminal amidation peptide hormones pharmacokinetics half-life extension thema EDItEUR::P Mathematics and Science::PS Biology, life sciences As proteins and peptides are the most abundant and versatile biomolecules, playing many critical roles in nearly every life process, many proteins/peptides are also strongly associated with human health and diseases. Various protein/peptide molecules have been proposed as biomarkers with potential diagnostic or prognostic value, and renewed interests in exploring peptides/proteins as crucial targets for therapeutic purposes have arisen. Bioactive proteins/peptides including various enzymes, antibodies, and peptide hormones have been developed and serve as biopharmaceuticals for clinical use. In addition, the advances in protein/peptide technology include the development of pharmaceutical molecular platforms such as peptide nanoparticles and drug delivery systems. This Special Issue aimed to present research articles that address the topic of biopharmaceutical proteins/peptides. Studies that contribute to advancing the molecular engineering and production process of biopharmaceutical peptides/proteins, as well as papers providing novel application-oriented perspectives, were also included. 2025-08-12T09:20:29Z 2025-08-12T09:20:29Z 2025 book ONIX_20250812T110751_9783725835645_73 9783725835645 9783725835638 https://directory.doabooks.org/handle/20.500.12854/165317 eng image/jpeg Attribution 4.0 International https://mdpi.com/books https://mdpi.com/books/pdfview/book/10685 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-3563-8 10.3390/books978-3-7258-3563-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725835645 9783725835638 216 open access |
| spellingShingle | glioma radiation proteomic valproic acid HDAC inhibitor collagen-derived peptide Prolyl-hydroxyproline muscle atrophy mouse C2C12 skeletal myotubes ubiquitin ligases Aedes aegypti adipokinetic hormone corazonin hormone molecular modelling yellow fever mosquito peptide signalling antimicrobial peptides host defense peptides LL37 structure biophysical human antimicrobial peptides photodynamic therapy anticancer therapy bioconjugate peptide derivatives nanoparticle bioactive peptides genetic engineering heterologous expression high-throughput screening RiPPs synthetic biology peptide synthesis antimicrobial cyclic peptide murepavadin acylation agents solid phase antibiotic antibacterial activity prothrombin activator RAPClot™ prototype tube ?-radiation enzymatic activity blood clotting serum biochemical analytes antimicrobial peptide rattusin antibiotics DNA binding cytotoxicity melittin 6-aminohexanoic acid leucine drug-resistant bacteria 1,2,4-triazoles antifungal peptides synthesis dipeptides fluconazole non-protein amino acids Aspergillus candidus Aspergillus versicolor Aspergillus flavus Alternaria alternate Ulocladium botrytis Aureobasidium pullulans peptidylglycine alpha-amidating monooxygenase C-terminal amidation peptide hormones pharmacokinetics half-life extension thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Development, Characterization, and Application of Bioactive Peptides, Diagnostic Biomarkers, and Pharmaceutical Proteins |
| title | Development, Characterization, and Application of Bioactive Peptides, Diagnostic Biomarkers, and Pharmaceutical Proteins |
| title_full | Development, Characterization, and Application of Bioactive Peptides, Diagnostic Biomarkers, and Pharmaceutical Proteins |
| title_fullStr | Development, Characterization, and Application of Bioactive Peptides, Diagnostic Biomarkers, and Pharmaceutical Proteins |
| title_full_unstemmed | Development, Characterization, and Application of Bioactive Peptides, Diagnostic Biomarkers, and Pharmaceutical Proteins |
| title_short | Development, Characterization, and Application of Bioactive Peptides, Diagnostic Biomarkers, and Pharmaceutical Proteins |
| title_sort | development characterization and application of bioactive peptides diagnostic biomarkers and pharmaceutical proteins |
| topic | glioma radiation proteomic valproic acid HDAC inhibitor collagen-derived peptide Prolyl-hydroxyproline muscle atrophy mouse C2C12 skeletal myotubes ubiquitin ligases Aedes aegypti adipokinetic hormone corazonin hormone molecular modelling yellow fever mosquito peptide signalling antimicrobial peptides host defense peptides LL37 structure biophysical human antimicrobial peptides photodynamic therapy anticancer therapy bioconjugate peptide derivatives nanoparticle bioactive peptides genetic engineering heterologous expression high-throughput screening RiPPs synthetic biology peptide synthesis antimicrobial cyclic peptide murepavadin acylation agents solid phase antibiotic antibacterial activity prothrombin activator RAPClot™ prototype tube ?-radiation enzymatic activity blood clotting serum biochemical analytes antimicrobial peptide rattusin antibiotics DNA binding cytotoxicity melittin 6-aminohexanoic acid leucine drug-resistant bacteria 1,2,4-triazoles antifungal peptides synthesis dipeptides fluconazole non-protein amino acids Aspergillus candidus Aspergillus versicolor Aspergillus flavus Alternaria alternate Ulocladium botrytis Aureobasidium pullulans peptidylglycine alpha-amidating monooxygenase C-terminal amidation peptide hormones pharmacokinetics half-life extension thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | glioma radiation proteomic valproic acid HDAC inhibitor collagen-derived peptide Prolyl-hydroxyproline muscle atrophy mouse C2C12 skeletal myotubes ubiquitin ligases Aedes aegypti adipokinetic hormone corazonin hormone molecular modelling yellow fever mosquito peptide signalling antimicrobial peptides host defense peptides LL37 structure biophysical human antimicrobial peptides photodynamic therapy anticancer therapy bioconjugate peptide derivatives nanoparticle bioactive peptides genetic engineering heterologous expression high-throughput screening RiPPs synthetic biology peptide synthesis antimicrobial cyclic peptide murepavadin acylation agents solid phase antibiotic antibacterial activity prothrombin activator RAPClot™ prototype tube ?-radiation enzymatic activity blood clotting serum biochemical analytes antimicrobial peptide rattusin antibiotics DNA binding cytotoxicity melittin 6-aminohexanoic acid leucine drug-resistant bacteria 1,2,4-triazoles antifungal peptides synthesis dipeptides fluconazole non-protein amino acids Aspergillus candidus Aspergillus versicolor Aspergillus flavus Alternaria alternate Ulocladium botrytis Aureobasidium pullulans peptidylglycine alpha-amidating monooxygenase C-terminal amidation peptide hormones pharmacokinetics half-life extension thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20250812T110751_9783725835645_73 |