Molecular Research in Obesity
The prevalence of obesity continues to rise worldwide, contributing to an increased burden of metabolic disorders such as type 2 diabetes, dyslipidemia, and cardiovascular diseases. While environmental factors play a significant role in this epidemic, genetic predisposition and dysfunctions in adipo...
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| Format: | Online |
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| Jezik: | engleski |
| Izdano: |
MDPI - Multidisciplinary Digital Publishing Institute
2025
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| Teme: | |
| Online pristup: | ONIX_20250812T110751_9783725837878_181 |
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| _version_ | 1869526560772456448 |
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| collection | Directory of Open Access Books |
| description | The prevalence of obesity continues to rise worldwide, contributing to an increased burden of metabolic disorders such as type 2 diabetes, dyslipidemia, and cardiovascular diseases. While environmental factors play a significant role in this epidemic, genetic predisposition and dysfunctions in adipose tissue remain critical determinants of disease onset and progression. The classical understanding of obesity, centered on energy imbalance and excessive fat accumulation, is being expanded thanks to emerging molecular insights into metabolic regulation, chronic low-grade inflammation, and adipose tissue plasticity. This Special Issue explores the interplay between traditional and novel mechanisms underlying obesity, including the molecular pathways regulating appetite, thermogenesis, adipocyte differentiation, and systemic inflammation. It also examines the roles of genetic and epigenetic factors in individual susceptibility and disease progression. Understanding these mechanisms is essential for developing innovative therapeutic strategies for preventing and managing obesity and its related complications. This Reprint provides a comprehensive overview of the latest advances in obesity research, highlighting new potential biomarkers and therapeutic targets that could transform future interventions in metabolic health. |
| format | Online |
| id | doab-20.500.12854ir-165426 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1654262025-08-12T09:30:13Z Molecular Research in Obesity Abad-Jiménez, Zaida Vezza, Teresa obesity adipose tissue molecular pathways metabolism new targets for treatment thema EDItEUR::M Medicine and Nursing The prevalence of obesity continues to rise worldwide, contributing to an increased burden of metabolic disorders such as type 2 diabetes, dyslipidemia, and cardiovascular diseases. While environmental factors play a significant role in this epidemic, genetic predisposition and dysfunctions in adipose tissue remain critical determinants of disease onset and progression. The classical understanding of obesity, centered on energy imbalance and excessive fat accumulation, is being expanded thanks to emerging molecular insights into metabolic regulation, chronic low-grade inflammation, and adipose tissue plasticity. This Special Issue explores the interplay between traditional and novel mechanisms underlying obesity, including the molecular pathways regulating appetite, thermogenesis, adipocyte differentiation, and systemic inflammation. It also examines the roles of genetic and epigenetic factors in individual susceptibility and disease progression. Understanding these mechanisms is essential for developing innovative therapeutic strategies for preventing and managing obesity and its related complications. This Reprint provides a comprehensive overview of the latest advances in obesity research, highlighting new potential biomarkers and therapeutic targets that could transform future interventions in metabolic health. 2025-08-12T09:30:10Z 2025-08-12T09:30:10Z 2025 book ONIX_20250812T110751_9783725837878_181 9783725837878 9783725837885 https://directory.doabooks.org/handle/20.500.12854/165426 eng image/jpeg Attribution 4.0 International https://mdpi.com/books https://mdpi.com/books/pdfview/book/10935 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-3788-5 10.3390/books978-3-7258-3788-5 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725837878 9783725837885 192 open access |
| spellingShingle | obesity adipose tissue molecular pathways metabolism new targets for treatment thema EDItEUR::M Medicine and Nursing Molecular Research in Obesity |
| title | Molecular Research in Obesity |
| title_full | Molecular Research in Obesity |
| title_fullStr | Molecular Research in Obesity |
| title_full_unstemmed | Molecular Research in Obesity |
| title_short | Molecular Research in Obesity |
| title_sort | molecular research in obesity |
| topic | obesity adipose tissue molecular pathways metabolism new targets for treatment thema EDItEUR::M Medicine and Nursing |
| topic_facet | obesity adipose tissue molecular pathways metabolism new targets for treatment thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20250812T110751_9783725837878_181 |