Molecular Mechanisms in Demyelinating Disorders of the Central Nervous System
This Special Issue reprint explores the molecular mechanisms driving myelin formation, maintenance, and breakdown within the central nervous system, offering a focused insight into demyelinating disorders such as multiple sclerosis. The article “Exploring Myelin Dynamics in Demyelinating Disorders a...
Wedi'i Gadw mewn:
| Fformat: | Online |
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| Iaith: | Saesneg |
| Cyhoeddwyd: |
MDPI - Multidisciplinary Digital Publishing Institute
2025
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| Pynciau: | |
| Mynediad Ar-lein: | ONIX_20250812T110751_9783725842759_409 |
| Tagiau: |
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
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| _version_ | 1869521403086110720 |
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| collection | Directory of Open Access Books |
| description | This Special Issue reprint explores the molecular mechanisms driving myelin formation, maintenance, and breakdown within the central nervous system, offering a focused insight into demyelinating disorders such as multiple sclerosis. The article “Exploring Myelin Dynamics in Demyelinating Disorders at the Molecular Level” offers a curated overview of recent advances in oligodendrocyte biology, highlighting key regulatory pathways, transcription factors, and cellular interactions that govern myelin dynamics. Drawing from ten representative studies, it emphasizes the translational relevance of early developmental signals, the role of neural and immune system cross-talk, and promising regenerative strategies. Particular attention is given to how molecular and cellular processes contribute to disease progression and to how targeted interventions might reshape current therapeutic approaches. This reprint is especially valuable for researchers and clinicians interested in neuroregeneration, glial biology, and CNS pathophysiology, providing a concise yet comprehensive synthesis of current trends in demyelination research. |
| format | Online |
| id | doab-20.500.12854ir-165654 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1656542025-08-12T10:04:02Z Molecular Mechanisms in Demyelinating Disorders of the Central Nervous System Theotokis, Paschalis demyelination molecular mechanisms oligodendrocyte precursor cells myelinogenesis dysmyelination lipid metabolism microglia and macrophages experimental autoimmune encephalomyelitis biomarkers remyelination transmission electron microscopy (TEM) thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences This Special Issue reprint explores the molecular mechanisms driving myelin formation, maintenance, and breakdown within the central nervous system, offering a focused insight into demyelinating disorders such as multiple sclerosis. The article “Exploring Myelin Dynamics in Demyelinating Disorders at the Molecular Level” offers a curated overview of recent advances in oligodendrocyte biology, highlighting key regulatory pathways, transcription factors, and cellular interactions that govern myelin dynamics. Drawing from ten representative studies, it emphasizes the translational relevance of early developmental signals, the role of neural and immune system cross-talk, and promising regenerative strategies. Particular attention is given to how molecular and cellular processes contribute to disease progression and to how targeted interventions might reshape current therapeutic approaches. This reprint is especially valuable for researchers and clinicians interested in neuroregeneration, glial biology, and CNS pathophysiology, providing a concise yet comprehensive synthesis of current trends in demyelination research. 2025-08-12T10:04:00Z 2025-08-12T10:04:00Z 2025 book ONIX_20250812T110751_9783725842759_409 9783725842759 9783725842766 https://directory.doabooks.org/handle/20.500.12854/165654 eng image/jpeg Attribution 4.0 International https://mdpi.com/books https://mdpi.com/books/pdfview/book/11074 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-4276-6 10.3390/books978-3-7258-4276-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725842759 9783725842766 234 open access |
| spellingShingle | demyelination molecular mechanisms oligodendrocyte precursor cells myelinogenesis dysmyelination lipid metabolism microglia and macrophages experimental autoimmune encephalomyelitis biomarkers remyelination transmission electron microscopy (TEM) thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Molecular Mechanisms in Demyelinating Disorders of the Central Nervous System |
| title | Molecular Mechanisms in Demyelinating Disorders of the Central Nervous System |
| title_full | Molecular Mechanisms in Demyelinating Disorders of the Central Nervous System |
| title_fullStr | Molecular Mechanisms in Demyelinating Disorders of the Central Nervous System |
| title_full_unstemmed | Molecular Mechanisms in Demyelinating Disorders of the Central Nervous System |
| title_short | Molecular Mechanisms in Demyelinating Disorders of the Central Nervous System |
| title_sort | molecular mechanisms in demyelinating disorders of the central nervous system |
| topic | demyelination molecular mechanisms oligodendrocyte precursor cells myelinogenesis dysmyelination lipid metabolism microglia and macrophages experimental autoimmune encephalomyelitis biomarkers remyelination transmission electron microscopy (TEM) thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | demyelination molecular mechanisms oligodendrocyte precursor cells myelinogenesis dysmyelination lipid metabolism microglia and macrophages experimental autoimmune encephalomyelitis biomarkers remyelination transmission electron microscopy (TEM) thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20250812T110751_9783725842759_409 |