Targeting Oxidative Stress for Disease
Oxidative stress (OS), representing an imbalance between the production of reactive oxygen species (ROS) and the body’s antioxidant defense systems, is a critical factor in the pathogenesis of numerous diseases, including neurodegenerative and psychiatric disorders, as well as cancer and cardiovascu...
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| Format: | Online |
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| Jezik: | angleščina |
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MDPI - Multidisciplinary Digital Publishing Institute
2025
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| Teme: | |
| Online dostop: | ONIX_20250812T110751_9783725843237_432 |
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| _version_ | 1869519161722404864 |
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| collection | Directory of Open Access Books |
| description | Oxidative stress (OS), representing an imbalance between the production of reactive oxygen species (ROS) and the body’s antioxidant defense systems, is a critical factor in the pathogenesis of numerous diseases, including neurodegenerative and psychiatric disorders, as well as cancer and cardiovascular and inflammatory conditions. The Special Issue, “Targeting Oxidative Stress for Disease”, brings together recent findings exploring the contribution of ROS and disturbed redox balance in disease development and progression, as well as potential approaches to counteract their effects. Highlighted topics include the impact of OS on neurodevelopment and psychiatric conditions, such as autism spectrum disorder (ASD), where OS markers may serve as early diagnostic tools or therapeutic targets. Studies featured in this Special Issue investigate the regulatory role of circular RNAs in response to OS during neuronal differentiation, and the contribution of ferroptosis to ASD pathology. Furthermore, this issue addresses the dual roles of neuropsychiatric medications in modulating redox balance and emphasizes the need for rigorous clinical trials to evaluate the efficacy of antioxidant and anti-inflammatory interventions. This Special Issue advances our understanding of OS-related pathophysiology and paves the way toward innovative redox-based therapeutic approaches. |
| format | Online |
| id | doab-20.500.12854ir-165677 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1656772025-08-12T10:06:09Z Targeting Oxidative Stress for Disease Orsolic, Nada Jazvinšćak Jembrek, Maja oxidants and free radical production physiological activities of free radicals detrimental effects of free radicals on human health ROS and ROS-mediated cellular signaling pathophysiology of oxidative stress biomarkers of oxidative stress chronic degenerative diseases therapeutic approaches targeting oxidative stress biochemical/molecular targets of chronic diseases exogenous antioxidants and human health flavonoids and redox biology in the pathophysiology of diseases pro-oxidative role of antioxidants: double-sided sword prooxidant agents in therapy thema EDItEUR::M Medicine and Nursing Oxidative stress (OS), representing an imbalance between the production of reactive oxygen species (ROS) and the body’s antioxidant defense systems, is a critical factor in the pathogenesis of numerous diseases, including neurodegenerative and psychiatric disorders, as well as cancer and cardiovascular and inflammatory conditions. The Special Issue, “Targeting Oxidative Stress for Disease”, brings together recent findings exploring the contribution of ROS and disturbed redox balance in disease development and progression, as well as potential approaches to counteract their effects. Highlighted topics include the impact of OS on neurodevelopment and psychiatric conditions, such as autism spectrum disorder (ASD), where OS markers may serve as early diagnostic tools or therapeutic targets. Studies featured in this Special Issue investigate the regulatory role of circular RNAs in response to OS during neuronal differentiation, and the contribution of ferroptosis to ASD pathology. Furthermore, this issue addresses the dual roles of neuropsychiatric medications in modulating redox balance and emphasizes the need for rigorous clinical trials to evaluate the efficacy of antioxidant and anti-inflammatory interventions. This Special Issue advances our understanding of OS-related pathophysiology and paves the way toward innovative redox-based therapeutic approaches. 2025-08-12T10:06:07Z 2025-08-12T10:06:07Z 2025 book ONIX_20250812T110751_9783725843237_432 9783725843237 9783725843244 https://directory.doabooks.org/handle/20.500.12854/165677 eng image/jpeg Attribution 4.0 International https://mdpi.com/books https://mdpi.com/books/pdfview/book/11003 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-4324-4 10.3390/books978-3-7258-4324-4 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725843237 9783725843244 286 open access |
| spellingShingle | oxidants and free radical production physiological activities of free radicals detrimental effects of free radicals on human health ROS and ROS-mediated cellular signaling pathophysiology of oxidative stress biomarkers of oxidative stress chronic degenerative diseases therapeutic approaches targeting oxidative stress biochemical/molecular targets of chronic diseases exogenous antioxidants and human health flavonoids and redox biology in the pathophysiology of diseases pro-oxidative role of antioxidants: double-sided sword prooxidant agents in therapy thema EDItEUR::M Medicine and Nursing Targeting Oxidative Stress for Disease |
| title | Targeting Oxidative Stress for Disease |
| title_full | Targeting Oxidative Stress for Disease |
| title_fullStr | Targeting Oxidative Stress for Disease |
| title_full_unstemmed | Targeting Oxidative Stress for Disease |
| title_short | Targeting Oxidative Stress for Disease |
| title_sort | targeting oxidative stress for disease |
| topic | oxidants and free radical production physiological activities of free radicals detrimental effects of free radicals on human health ROS and ROS-mediated cellular signaling pathophysiology of oxidative stress biomarkers of oxidative stress chronic degenerative diseases therapeutic approaches targeting oxidative stress biochemical/molecular targets of chronic diseases exogenous antioxidants and human health flavonoids and redox biology in the pathophysiology of diseases pro-oxidative role of antioxidants: double-sided sword prooxidant agents in therapy thema EDItEUR::M Medicine and Nursing |
| topic_facet | oxidants and free radical production physiological activities of free radicals detrimental effects of free radicals on human health ROS and ROS-mediated cellular signaling pathophysiology of oxidative stress biomarkers of oxidative stress chronic degenerative diseases therapeutic approaches targeting oxidative stress biochemical/molecular targets of chronic diseases exogenous antioxidants and human health flavonoids and redox biology in the pathophysiology of diseases pro-oxidative role of antioxidants: double-sided sword prooxidant agents in therapy thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20250812T110751_9783725843237_432 |