Challenges in Diagnosis and Treatment of Infertility

The diagnosis and treatment of infertility are challenging due to issues related to precision required to address individual medical needs and personalized assisted reproduction applications. Age-related or gamete-depletion-related subfertility raises concerns about best practice modalities to warra...

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প্রকাশিত: MDPI - Multidisciplinary Digital Publishing Institute 2025
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অনলাইন ব্যবহার করুন:ONIX_20250812T110751_9783725843657_453
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collection Directory of Open Access Books
description The diagnosis and treatment of infertility are challenging due to issues related to precision required to address individual medical needs and personalized assisted reproduction applications. Age-related or gamete-depletion-related subfertility raises concerns about best practice modalities to warrant early diagnoses and prompt treatments to avoid further fertility loss or a significant reduction in a patient’s chances to conceive. Lately, technical advances in preimplantation diagnostic approaches, especially via the introduction of NGS, have offered novel insights into the genetic makeup of preimplantation embryos and even the clinical exploitation of mosaic embryos. Additionally, the treatment outcomes of cell therapies and growth factors showed significant improvements in the regeneration of ovaries and the uterus following the advent of PRP therapy. In all cases, technological innovations such as minimally invasive or non-invasive preimplantation genetic diagnosis improved the prognosis of ART and the prospects for a wider application. This reprint presents the latest innovations on recent clinical advances in fertility preservation diagnosis and treatment, as well as the improvement of prospects for the conception and reduction in the time to pregnancy.
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spelling doab-20.500.12854ir-1656982025-08-12T10:08:06Z Challenges in Diagnosis and Treatment of Infertility Zikopoulos, Konstantinos A. fertility in vitro fertilization assisted reproductive technology thema EDItEUR::M Medicine and Nursing The diagnosis and treatment of infertility are challenging due to issues related to precision required to address individual medical needs and personalized assisted reproduction applications. Age-related or gamete-depletion-related subfertility raises concerns about best practice modalities to warrant early diagnoses and prompt treatments to avoid further fertility loss or a significant reduction in a patient’s chances to conceive. Lately, technical advances in preimplantation diagnostic approaches, especially via the introduction of NGS, have offered novel insights into the genetic makeup of preimplantation embryos and even the clinical exploitation of mosaic embryos. Additionally, the treatment outcomes of cell therapies and growth factors showed significant improvements in the regeneration of ovaries and the uterus following the advent of PRP therapy. In all cases, technological innovations such as minimally invasive or non-invasive preimplantation genetic diagnosis improved the prognosis of ART and the prospects for a wider application. This reprint presents the latest innovations on recent clinical advances in fertility preservation diagnosis and treatment, as well as the improvement of prospects for the conception and reduction in the time to pregnancy. 2025-08-12T10:08:04Z 2025-08-12T10:08:04Z 2025 book ONIX_20250812T110751_9783725843657_453 9783725843657 9783725843664 https://directory.doabooks.org/handle/20.500.12854/165698 eng image/jpeg Attribution 4.0 International https://mdpi.com/books https://mdpi.com/books/pdfview/book/11106 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-4366-4 10.3390/books978-3-7258-4366-4 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725843657 9783725843664 206 open access
spellingShingle fertility
in vitro fertilization
assisted reproductive technology
thema EDItEUR::M Medicine and Nursing
Challenges in Diagnosis and Treatment of Infertility
title Challenges in Diagnosis and Treatment of Infertility
title_full Challenges in Diagnosis and Treatment of Infertility
title_fullStr Challenges in Diagnosis and Treatment of Infertility
title_full_unstemmed Challenges in Diagnosis and Treatment of Infertility
title_short Challenges in Diagnosis and Treatment of Infertility
title_sort challenges in diagnosis and treatment of infertility
topic fertility
in vitro fertilization
assisted reproductive technology
thema EDItEUR::M Medicine and Nursing
topic_facet fertility
in vitro fertilization
assisted reproductive technology
thema EDItEUR::M Medicine and Nursing
url ONIX_20250812T110751_9783725843657_453