Advances in Diagnosis and Treatment of Peritoneum Cancer
Approximately 4-10% of patients with tumors of the abdominal cavity have peritoneal metastasis (PM) at the time of diagnosis, while 20-40% will develop PM during the evolution of their tumor. Until recently, the diagnosis of PM was ominous and associated with severe and incapacitating symptoms, a po...
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| Formaat: | Online |
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| Taal: | Engels |
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MDPI - Multidisciplinary Digital Publishing Institute
2025
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| Online toegang: | ONIX_20250812T110751_9783725846030_559 |
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| _version_ | 1869514858184048640 |
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| collection | Directory of Open Access Books |
| description | Approximately 4-10% of patients with tumors of the abdominal cavity have peritoneal metastasis (PM) at the time of diagnosis, while 20-40% will develop PM during the evolution of their tumor. Until recently, the diagnosis of PM was ominous and associated with severe and incapacitating symptoms, a poor response to systemic chemotherapy, and a poor survival of 4-6 months. The scenario has changed following the introduction of a new generation of chemotherapy and agents against biological targets, as well as with the introduction of new combined therapies, including cytoreductive surgery and new diagnostic–therapeutic schemes. However, there are still many unresolved issues relating to the role, indications, and efficiency that these new therapeutic schemes may offer. We aimed to evaluate the latest knowledge in relation to PM with respect to the incidence, clinical and molecular prognostic factors, survival, and the role of surgical–chemotherapeutic techniques in this era of biological and immunotherapy agents. Special interest had been placed on colorectal, gastric, and ovarian cancer, as well as primary peritoneal cancer. |
| format | Online |
| id | doab-20.500.12854ir-165804 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1658042025-08-12T10:18:26Z Advances in Diagnosis and Treatment of Peritoneum Cancer Diez-Alonso, Manuel Gutierrez-Calvo, Alberto peritoneal metastasis peritoneal carcinomatosis colorectal cancer gastric cancer ovarian cancer surgery prognostic factors tumor recurrence adjuvant chemotherapy biological targeted therapy HIPEC EPIC cytoreductive surgery prophylactic second look surgery prophylactic laparotomy T4 thema EDItEUR::M Medicine and Nursing Approximately 4-10% of patients with tumors of the abdominal cavity have peritoneal metastasis (PM) at the time of diagnosis, while 20-40% will develop PM during the evolution of their tumor. Until recently, the diagnosis of PM was ominous and associated with severe and incapacitating symptoms, a poor response to systemic chemotherapy, and a poor survival of 4-6 months. The scenario has changed following the introduction of a new generation of chemotherapy and agents against biological targets, as well as with the introduction of new combined therapies, including cytoreductive surgery and new diagnostic–therapeutic schemes. However, there are still many unresolved issues relating to the role, indications, and efficiency that these new therapeutic schemes may offer. We aimed to evaluate the latest knowledge in relation to PM with respect to the incidence, clinical and molecular prognostic factors, survival, and the role of surgical–chemotherapeutic techniques in this era of biological and immunotherapy agents. Special interest had been placed on colorectal, gastric, and ovarian cancer, as well as primary peritoneal cancer. 2025-08-12T10:18:23Z 2025-08-12T10:18:23Z 2025 book ONIX_20250812T110751_9783725846030_559 9783725846030 9783725846047 https://directory.doabooks.org/handle/20.500.12854/165804 eng image/jpeg Attribution 4.0 International https://mdpi.com/books https://mdpi.com/books/pdfview/book/11209 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-4604-7 10.3390/books978-3-7258-4604-7 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725846030 9783725846047 138 open access |
| spellingShingle | peritoneal metastasis peritoneal carcinomatosis colorectal cancer gastric cancer ovarian cancer surgery prognostic factors tumor recurrence adjuvant chemotherapy biological targeted therapy HIPEC EPIC cytoreductive surgery prophylactic second look surgery prophylactic laparotomy T4 thema EDItEUR::M Medicine and Nursing Advances in Diagnosis and Treatment of Peritoneum Cancer |
| title | Advances in Diagnosis and Treatment of Peritoneum Cancer |
| title_full | Advances in Diagnosis and Treatment of Peritoneum Cancer |
| title_fullStr | Advances in Diagnosis and Treatment of Peritoneum Cancer |
| title_full_unstemmed | Advances in Diagnosis and Treatment of Peritoneum Cancer |
| title_short | Advances in Diagnosis and Treatment of Peritoneum Cancer |
| title_sort | advances in diagnosis and treatment of peritoneum cancer |
| topic | peritoneal metastasis peritoneal carcinomatosis colorectal cancer gastric cancer ovarian cancer surgery prognostic factors tumor recurrence adjuvant chemotherapy biological targeted therapy HIPEC EPIC cytoreductive surgery prophylactic second look surgery prophylactic laparotomy T4 thema EDItEUR::M Medicine and Nursing |
| topic_facet | peritoneal metastasis peritoneal carcinomatosis colorectal cancer gastric cancer ovarian cancer surgery prognostic factors tumor recurrence adjuvant chemotherapy biological targeted therapy HIPEC EPIC cytoreductive surgery prophylactic second look surgery prophylactic laparotomy T4 thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20250812T110751_9783725846030_559 |