Organoids for Personalised Cancer Medicine

This open access book builds on and updates work performed in the HYBRIDA project, funded by the EU to develop an ethical framework for organoid research. Organoids are three-dimensional stem cell constructs that mimic organs of the body or tumours. Patient-derived organoids are envisioned to be gro...

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-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Vogt, Henrik, Gaillard, Maxence, Green, Sara
Формат: Online
Хэл сонгох:англи
Хэвлэсэн: Springer Nature 2025
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Онлайн хандалт:ONIX_20250813T121456_9783031855351_3
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author Vogt, Henrik
Gaillard, Maxence
Green, Sara
author_browse Gaillard, Maxence
Green, Sara
Vogt, Henrik
author_facet Vogt, Henrik
Gaillard, Maxence
Green, Sara
author_sort Vogt, Henrik
collection Directory of Open Access Books
description This open access book builds on and updates work performed in the HYBRIDA project, funded by the EU to develop an ethical framework for organoid research. Organoids are three-dimensional stem cell constructs that mimic organs of the body or tumours. Patient-derived organoids are envisioned to be grown from individual patients’ tumours and used to tailor the most effective and safest treatments in a new form of personalized medicine. This text offers a critical assessment of this vision from the perspective of philosophy of medicine. The authors present a tailored “vision assessment”, presented as examples of methodological development, and applied to objects. They first analyse and describe the vision of using organoids for personalized cancer medicine, then critically evaluate this vision and finally comment on ethical implications of the epistemological issues and how to handle them. The authors further draw on sources for empirical inquiries. This book presents an exercise in health technology assessment conducted by philosophers. Its core readership are philosophers of medicine and bioethicists interested in personalized medicine and stem cell research.
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spelling doab-20.500.12854ir-1658702025-08-14T05:03:06Z Organoids for Personalised Cancer Medicine Vogt, Henrik Gaillard, Maxence Green, Sara health technology assessment vision assessment patient derived organoids precision medicine personalized medicine philosophy of medicine philosophy of technology ethical issues in biomedical research philosophy of models thema EDItEUR::Q Philosophy and Religion::QD Philosophy thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBD Medical profession::MBDC Medical ethics and professional conduct thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues This open access book builds on and updates work performed in the HYBRIDA project, funded by the EU to develop an ethical framework for organoid research. Organoids are three-dimensional stem cell constructs that mimic organs of the body or tumours. Patient-derived organoids are envisioned to be grown from individual patients’ tumours and used to tailor the most effective and safest treatments in a new form of personalized medicine. This text offers a critical assessment of this vision from the perspective of philosophy of medicine. The authors present a tailored “vision assessment”, presented as examples of methodological development, and applied to objects. They first analyse and describe the vision of using organoids for personalized cancer medicine, then critically evaluate this vision and finally comment on ethical implications of the epistemological issues and how to handle them. The authors further draw on sources for empirical inquiries. This book presents an exercise in health technology assessment conducted by philosophers. Its core readership are philosophers of medicine and bioethicists interested in personalized medicine and stem cell research. 2025-08-14T05:03:05Z 2025-08-14T05:03:05Z 2025-08-13T10:16:56Z 2025 book ONIX_20250813T121456_9783031855351_3 https://library.oapen.org/handle/20.500.12657/105411 9783031855351 9783031855344 https://directory.doabooks.org/handle/20.500.12854/165870 eng SpringerBriefs in Philosophy open access image/jpeg n/a https://library.oapen.org/bitstream/20.500.12657/105411/1/9783031855351.pdf Springer Nature Springer Nature Switzerland 10.1007/978-3-031-85535-1 10.1007/978-3-031-85535-1 9fa3421d-f917-4153-b9ab-fc337c396b5a b77fb797-b1d1-44fb-a755-1b44fe24463c 3983007a-5726-4f1e-b9df-3fbc771f2916 9783031855351 9783031855344 EU collection Springer Nature Switzerland 126 Cham [...] European Commission European Union 10.13039/501100000780 open access
spellingShingle health technology assessment
vision assessment
patient derived organoids
precision medicine
personalized medicine
philosophy of medicine
philosophy of technology
ethical issues in biomedical research
philosophy of models
thema EDItEUR::Q Philosophy and Religion::QD Philosophy
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBD Medical profession::MBDC Medical ethics and professional conduct
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
Vogt, Henrik
Gaillard, Maxence
Green, Sara
Organoids for Personalised Cancer Medicine
title Organoids for Personalised Cancer Medicine
title_full Organoids for Personalised Cancer Medicine
title_fullStr Organoids for Personalised Cancer Medicine
title_full_unstemmed Organoids for Personalised Cancer Medicine
title_short Organoids for Personalised Cancer Medicine
title_sort organoids for personalised cancer medicine
topic health technology assessment
vision assessment
patient derived organoids
precision medicine
personalized medicine
philosophy of medicine
philosophy of technology
ethical issues in biomedical research
philosophy of models
thema EDItEUR::Q Philosophy and Religion::QD Philosophy
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBD Medical profession::MBDC Medical ethics and professional conduct
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
topic_facet health technology assessment
vision assessment
patient derived organoids
precision medicine
personalized medicine
philosophy of medicine
philosophy of technology
ethical issues in biomedical research
philosophy of models
thema EDItEUR::Q Philosophy and Religion::QD Philosophy
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBD Medical profession::MBDC Medical ethics and professional conduct
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
url ONIX_20250813T121456_9783031855351_3
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