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IMMUNO-model in Cancer

This open access volume describes the computational and experimental models that help researchers understand the responses of the immune system in cancer and test experimental immune-oncology approaches. The chapters in this book cover methods such as profile polarization in macrophages using ELISA;...

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Salvato in:
Natura: Online
Lingua:inglese
Pubblicazione: Springer Nature 2025
Soggetti:
Open Access
Dendritic Cell Activation
breast cancer cell lines
Immunohistochemistry
macrophage polarization
myeloid-derived suppressor cells
MDSC
T-cell killing assay
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCM Immunology
Accesso online:ONIX_20251020T130859_9781071647349_40
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Riassunto:This open access volume describes the computational and experimental models that help researchers understand the responses of the immune system in cancer and test experimental immune-oncology approaches. The chapters in this book cover methods such as profile polarization in macrophages using ELISA; immune checkpoint inhibitors; interactions of PD-1/PD-L1 and T cells; immunocompetent preclinical mouse models to study primary and metastatic brain cancer; and methods to generate CAR T-cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Immuno-Model in Cancer: Methods and Protocols is a valuable resource for both new and experienced researchers who want to learn more about this important and developing field.

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